Reference : Changes in brain anatomy in focal hand dystonia
Scientific journals : Article
Human health sciences : Neurology
http://hdl.handle.net/2268/11341
Changes in brain anatomy in focal hand dystonia
English
Garraux, Gaëtan[Université de Liège - ULg & Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD > > > >]
Bauer, Andrew[Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD > > > > > >]
Hanakawa, Takashi[Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD > > > > > >]
Wu, Tao[Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD > > > > > >]
Kansaku, Kenji[Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD > > > > > >]
Hallett, M.[Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD > > > > > >]
[en] No consistent cerebral anatomical abnormality has ever been reported in primary focal hand dystonia (FHD). The present voxel-based morphometry study showed a significant bilateral increase in gray matter in the hand representation area of primary somatosensory and, to a lesser extent, primary motor cortices in 36 patients with unilateral FHD compared with 36 controls. The presence of anatomical changes in the perirolandic cortex for the unaffected hand as well as that for the affected hand suggests that these disturbances may be, at least in part, primary.
NINDS - National Institutes of Health - NIH - USA ; Fondation Horlait-Dapsens (University of Liège). ; Belgian American Educational Foundation - BAEF ; North Atlantic Treaty Organization (NATO) ; Fondation Léon Frédéricq (University of Liège). ; Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
[Université de Liège - ULg & Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD > > > >]
