Article (Scientific journals)
Optimization of blocked designs in fMRI studies
Maus, Bärbel; van Breukelen, G. J. P.; Goebel, R. et al.
2010In Psychometrika, 75 (2), p. 373–390
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Keywords :
blocked design; optimal design; fMRI; efficiency; maximin
Abstract :
[en] Blocked designs in functional magnetic resonance imaging (fMRI) are useful to localize functional brain areas. A blocked design consists of different blocks of trials of the same stimulus type and is characterized by three factors: the length of blocks, i.e., number of trials per blocks, the ordering of task and rest blocks, and the time between trials within one block. Optimal design theory was applied to find the optimal combination of these three design factors. Furthermore, different error structures were used within a general linear model for the analysis of fMRI data, and the maximin criterion was applied to find designs which are robust against misspecification of model parameters.
Disciplines :
Neurosciences & behavior
Author, co-author :
Maus, Bärbel ;  Maastricht University > Department of Methodology and Statistics
van Breukelen, G. J. P.
Goebel, R.
Berger, M. P. F.
Language :
English
Title :
Optimization of blocked designs in fMRI studies
Publication date :
2010
Journal title :
Psychometrika
ISSN :
0033-3123
eISSN :
1860-0980
Publisher :
Psychonomic Society, Research Triangle Park, United States - Virginia
Volume :
75
Issue :
2
Pages :
373–390
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 01 March 2012

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