ORBi: Salmon Eric - Predominant ventromedial frontopolar metabolic impairment in frontotemporal dementia

Reference : Predominant ventromedial frontopolar metabolic impairment in frontotemporal dementia


	Document type :	Scientific journals : Article
	Discipline(s) :	Human health sciences : Radiology, nuclear medicine & imaging Human health sciences : Neurology Social & behavioral sciences, psychology : Neurosciences & behavior
	To cite this reference:	http://hdl.handle.net/2268/11321

Title :	Predominant ventromedial frontopolar metabolic impairment in frontotemporal dementia
Language :	English
Author, co-author :	Salmon, Eric [Université de Liège - ULg > Centre de Recherches du Cyclotron et Département des sciences cliniques > Neurologie > >]
	Garraux, Gaëtan [Université de Liège - ULg > Centre de Recherches du Cyclotron et Département des sciences cliniques > Neurologie > > >]
	Delbeuck, Xavier [Université de Liège - ULG > Département des sciences cognitives > Neuropsychologie > >]
	Collette, Fabienne [Université de Liège - ULg > Département des sciences cognitives > Neuropsychologie > > >]
	Kalbe, Elke [Department of Neurology, University of Cologne, and Max-Planck Institute for Neurological Research, Cologne, Germany > > > > > >]
	Zuendorf, Gerhard [Department of Neurology, University of Cologne, and Max-Planck Institute for Neurological Research, Cologne, Germany > > > > > >]
	Perani, Daniela [INB-CNR, Universities Vita-Salute HSR and Milano-Bicocca, Scientific Institute HSR, Milano, Italy > > > > > >]
	Fazio, Ferruccio [INB-CNR, Universities Vita-Salute HSR and Milano-Bicocca, Scientific Institute HSR, Milano, Italy > > > > > >]
	Herholz, Karl [Department of Neurology, University of Cologne, and Max-Planck Institute for Neurological Research, Cologne, Germany > > > > > >]
Publication date :	Sep-2003
Journal title :	NeuroImage
Publisher :	Academic Press Inc Elsevier Science
Volume :	20
Issue/season :	1
Pages :	435-440
Peer reviewed :	Yes (verified by ORBi)
Audience :	International
ISSN :	1053-8119
City :	San Diego
Keywords :	[en] dementia ; PET
Abstract :	[en] In a multicenter study, FDG-PET images in a population of 29 patients with frontotemporal dementia (FTD) were compared to controls with similar age from each center. A conjunction analysis led to identification of the ventromedial frontopolar cortex as the single region affected in each and every FTD patients. This precise regional metabolic impairment should be integrated with recent neuropsychological researches, such as those showing that the ventromedial frontal cortex is critically involved in decision-making processes based on personal experience, feelings of rightness or social knowledge, processes that are characteristically impaired in FTD. (C) 2003 Elsevier Inc. All rights reserved.
Research units :	Centre de Recherches du Cyclotron - CRC
Funders :	Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
Target :	Researchers ; Professionals
Permalink :	http://hdl.handle.net/2268/11321
DOI :	10.1016/S1053-8119(03)00346-X
Other URL :	http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WNP-4991PTP-G&_user=532038&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000026659&_version=1&_urlVersion=0&_userid=532038&md5=06ba2d0e2630f048788c0c7ef52484fa

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