Reference : Predominant ventromedial frontopolar metabolic impairment in frontotemporal dementia
Scientific journals : Article
Social & behavioral sciences, psychology : Neurosciences & behavior
Human health sciences : Neurology
Human health sciences : Radiology, nuclear medicine & imaging
http://hdl.handle.net/2268/11321
Predominant ventromedial frontopolar metabolic impairment in frontotemporal dementia
English
Salmon, Eric mailto [Université de Liège - ULg > Centre de Recherches du Cyclotron et Département des sciences cliniques > Neurologie > >]
Garraux, Gaëtan mailto [Université de Liège - ULg > Centre de Recherches du Cyclotron et Département des sciences cliniques > Neurologie > > >]
Delbeuck, Xavier [Université de Liège - ULG > Département des sciences cognitives > Neuropsychologie > >]
Collette, Fabienne mailto [Université de Liège - ULg > Département des sciences cognitives > Neuropsychologie > > >]
Kalbe, Elke [Department of Neurology, University of Cologne, and Max-Planck Institute for Neurological Research, Cologne, Germany > > > > > >]
Zuendorf, Gerhard [Department of Neurology, University of Cologne, and Max-Planck Institute for Neurological Research, Cologne, Germany > > > > > >]
Perani, Daniela [INB-CNR, Universities Vita-Salute HSR and Milano-Bicocca, Scientific Institute HSR, Milano, Italy > > > > > >]
Fazio, Ferruccio [INB-CNR, Universities Vita-Salute HSR and Milano-Bicocca, Scientific Institute HSR, Milano, Italy > > > > > >]
Herholz, Karl [Department of Neurology, University of Cologne, and Max-Planck Institute for Neurological Research, Cologne, Germany > > > > > >]
Sep-2003
NeuroImage
Academic Press Inc Elsevier Science
20
1
435-440
Yes (verified by ORBi)
International
1053-8119
San Diego
[en] dementia ; PET
[en] In a multicenter study, FDG-PET images in a population of 29 patients with frontotemporal dementia (FTD) were compared to controls with similar age from each center. A conjunction analysis led to identification of the ventromedial frontopolar cortex as the single region affected in each and every FTD patients. This precise regional metabolic impairment should be integrated with recent neuropsychological researches, such as those showing that the ventromedial frontal cortex is critically involved in decision-making processes based on personal experience, feelings of rightness or social knowledge, processes that are characteristically impaired in FTD. (C) 2003 Elsevier Inc. All rights reserved.
Centre de Recherches du Cyclotron - CRC
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
Researchers ; Professionals
http://hdl.handle.net/2268/11321
10.1016/S1053-8119(03)00346-X
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WNP-4991PTP-G&_user=532038&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000026659&_version=1&_urlVersion=0&_userid=532038&md5=06ba2d0e2630f048788c0c7ef52484fa

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