ORBi: De Roover Arnaud - Pancreas graft drainage in recipient duodenum: Preliminary experience

Reference : Pancreas graft drainage in recipient duodenum: Preliminary experience


	Document type :	Scientific journals : Article
	Discipline(s) :	Human health sciences : Endocrinology, metabolism & nutrition Human health sciences : Surgery Human health sciences : Immunology & infectious disease
	To cite this reference:	http://hdl.handle.net/2268/1130

Title :	Pancreas graft drainage in recipient duodenum: Preliminary experience
Language :	English
Author, co-author :	De Roover, Arnaud [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
	Coimbra Marques, Carla [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
	Detry, Olivier [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
	Van Kemseke, Catherine [Centre Hospitalier Universitaire de Liège - CHU > > Gastro-Entérologie-Hépatologie >]
	Squifflet, Jean-Paul [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
	Honore, Pierre [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
	Meurisse, Michel [Université de Liège - ULg > Département des sciences cliniques > Chirurgicale abdominale]
Publication date :	27-Sep-2007
Journal title :	Transplantation
Publisher :	Lippincott Williams & Wilkins
Volume :	84
Issue/season :	6
Pages :	795-797
Audience :	International
ISSN :	0041-1337
City :	Philadelphia
Keywords :	[en] pancreas ; transplantation ; monitoring ; rejection ; diabetes
Abstract :	[en] Pancreas graft survival has continuously improved over the years to become a main treatment option of uncontrolled complicated diabetes. Rejection remains the major challenge as it often goes unnoticed until severe damage of the graft manifests itself by elevated blood sugar. Pancreas enzymes monitoring in the blood and in the urine is a sensitive marker of rejection but lack of specificity. Biopsy remains the gold standard. Cystoscopy-guided biopsy of bladder-drained pancreas has a good success rate for obtaining tissue but the vesical drainage exposes to metabolic and urologic morbidity. Percutaneous pancreas biopsy can be performed with a low morbidity rate but severe complications can occur. We discuss a technique of pancreas transplantation with the drainage of exocrine secretions of the pancreatic graft in the recipient duodenum, which permits easy monitoring of the graft by upper endoscopy of the duodenum.
Target :	Professionals ; Students
Permalink :	http://hdl.handle.net/2268/1130
DOI :	10.1097/01.tp.0000281401.88231.da

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