Article (Scientific journals)
Cardiac myxoma in a 6-year-old child--constitutional symptoms mimicking rheumatic disease and the role of interleukin-6.
Hovels-Gurich, H. H.; SEGHAYE, Marie-Christine; Amo-Takyi, B. K. et al.
1999In Acta Paediatrica, 88 (7), p. 786-8
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Keywords :
Child; Echocardiography; Female; Heart Atria/surgery; Heart Neoplasms/diagnosis/surgery; Humans; Immunohistochemistry; Interleukin-6/blood; Myxoma/diagnosis/surgery; Rheumatic Diseases/diagnosis; Tumor Markers, Biological/blood
Abstract :
[en] A 6-y-old girl with right atrial myxoma presented with remittent fever attacks, general arthralgia and laboratory investigations mimicking rheumatic or autoimmune disease. Interleukin-6 (IL-6) serum concentration was markedly elevated before and normal after tumour resection, whereas myxoma cells stained negatively for IL-6. IL-6 should be considered a myxoma marker: overproduction by myxoma cells and consecutive systemic passage are assumed to cause immunological features.
Disciplines :
Pediatrics
Author, co-author :
Hovels-Gurich, H. H.;  Rheinisch - Westfälische Technische Hochschule Aachen - RWTH > Pediatric Cardiology
SEGHAYE, Marie-Christine ;  Rheinisch - Westfälische Technische Hochschule Aachen - RWTH > Pediatric Cardiology
Amo-Takyi, B. K.;  Rheinisch - Westfälische Technische Hochschule Aachen - RWTH > Pathology
Hugel, W.;  Rheinisch - Westfälische Technische Hochschule Aachen - RWTH > Cardiovascular Surgery
Duchateau, J.;  Hôpital Brugman Bruxelles > Immunology
von Bernuth, G.;  Rheinisch - Westfälische Technische Hochschule Aachen - RWTH > Pediatric Cardiology
Language :
English
Title :
Cardiac myxoma in a 6-year-old child--constitutional symptoms mimicking rheumatic disease and the role of interleukin-6.
Publication date :
July 1999
Journal title :
Acta Paediatrica
ISSN :
0803-5253
eISSN :
1651-2227
Publisher :
Taylor & Francis, Oslo, Norway
Volume :
88
Issue :
7
Pages :
786-8
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 27 February 2012

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