Chronic Idiopathic Penile Edema: Three Cases and a Review of the Literature

[en] Abstract: Chronic idiopathic penile edema (CIPE) is an exceptional entity with disabling persistent lymphedema of the penis, affecting accessorily the scrotum and the pubis. The onset presents with recurrent swelling of the external genitalia, regressing spontaneously. After 2-3 years the swelling becomes progressively persistent. Mictional and erectile dysfunctions are not uncommon. A thorough work-up including RX, ultrasound examination, CT scanning, MRI imaging, serology and extensive blood testing should be performed to exclude underlying causes, including neoplastic, infectious, vascular and inflammatory diseases. CIPE is associated with significant psychological and functional impact. Surgical correction is the sole therapeutic option. Three patients with CIPE and a review of the literature are presented in order to increase awareness of this rare condition.

Disciplines :

Dermatology

Author, co-author :

RATY, Laurent ; Centre Hospitalier Universitaire de Liège - CHU > Dermatologie

FAILLA, Valérie ; Centre Hospitalier Universitaire de Liège - CHU > Dermatologie

Andrianne, Robert ; Université de Liège - ULiège > Département des sciences cliniques > Urologie

FILLET, Marc ; Centre Hospitalier Universitaire de Liège - CHU > Urologie

Waltregny, David ; Université de Liège - ULiège > Département des sciences cliniques > Urologie

NIKKELS, Arjen ; Centre Hospitalier Universitaire de Liège - CHU > Dermatologie

Language :

English

Title :

Chronic Idiopathic Penile Edema: Three Cases and a Review of the Literature

Publication date :

05 January 2011

Journal title :

Open Dermatology Journal

eISSN :

1874-3722

Publisher :

Bentham Open

Volume :

Pages :

1-5

Peer reviewed :

Peer reviewed

Available on ORBi :

since 26 February 2012

Statistics

Number of views

410 (17 by ULiège)

Number of downloads

1610 (8 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenCitations

Bibliography

Smeltzer DM, Stickler GB, Schirger A. Primary lymphedema in children and adolescents: a follow-up study and review. Pediatrics 1985; 76: 206-18.
McDougal WS. Lymphedema of the external genitalia. J Urol 2003; 170: 711-6.
van Langen AM, Gal S, Hulsmann AR, De Nef JJ. Acute idiopathic scrotal oedema: four cases and a short review. Eur J Pediatr 2001; 160: 455-6.
Geyer H, Geyer A, Schubert J. Erysipelas and elephantiasis of the scrotum. Surgical and drug therapy. Urologe-Ausgabe A 1995; 34: 59-61.
Murphy MJ, Kogan B, Carlson JA. Granulomatous lymphangitis of the scrotum and penis. Report of a case and review of the literature of genital swelling with sarcoidal granulomatous inflammation. J Cutan Pathol 2001; 28: 419-24.
Thomas JA, Matanhelia SS, Rees RWM. Recurrent adult idiopathic penile oedema: a new clinical entity? Hosp Update 1993; 667-8.
Porter W, Dinneen M, Bunker C. Chronic penile lymphedema: a report of 6 cases. Arch Dermatol 2001; 137: 1108-10.
Muehlberger T, Homann HH, Kuhnen C, Vogt PM, Steinau HU. Etiology, clinical aspects and therapy of penoscrotal lymphedema. Chirurg 2001; 72: 414-8.
Halperin TJ, Slavin SA, Olumi AF, Borud LJ. Surgical management of scrotal lymphedema using local flaps. Ann Plast Surg 2007; 59: 67-72.
Brandes SB, Chelsky MJ, Hanno PM. Adult acute idiopathic scrotal edema. Urology 1994; 44: 602-5.
Luelmo J, Tolosa C, Prats J, Bella MR, Saez A, Pellicé C Jr. Tumorous lymphedema of the penis. Report of verrucous elephantiasis. A brief case. Preliminary note. Actas Urol Esp 1995; 19: 585-7.
Tebbe-Gholami M, Roest W. A man with acute scrotal swelling. Ned Tijdschr Geneeskd 2010; 154: A16.
García-Tutor E, Botellé del Hierro J, San Martín Maya A, et al. Surgical treatment of penile lymphedema associated with hidradenitis suppurativa. Acta Urol Esp 2005; 29: 519-22.
Fahal AH, Suliman SH, Sharfi AR, el Mahadi EM. Acute idiopathic scrotal oedema in association with diabetic septic foot. Diabetes Res Clin Pract 1993; 21: 197-200.
Chen TC, Lu PL, Chen YH, Tsai JJ, Chen TP. Dengue hemorrhagic fever complicated with acute idiopathic scrotal edema and polyneuropathy. Am J Trop Med Hyg 2008; 78: 8-10.
Choong KK. Acute penoscrotal edema due to acute necrotizing pancreatitis. J Ultrasound Med 1996; 15: 247-8.
Malloy TR, Wein AJ, Gross P. Scrotal and penile lymphedema: surgical considerations and management. J Urol 1983; 130: 263-5.
Abraham G, Blake PG, Mathews RE, Bargman JM, Izatt S, Oreopoulos DG. Genital swelling as a surgical complication of continuous ambulatory peritoneal dialysis. Surg Gynecol Obstet 1990; 170: 306-8.
Wright RA, Judson FN. Penile veneral edema. JAMA 1979; 241: 157-8.
Hadway P, Lynch M, Corbishley CM, Mortimer PS, Watkin NA. Squamous cell carcinoma of the penis in a patient with chronic isolated penile lymphedema. Urol Int 2006; 76: 87-8.
Samsoen M, Deschler JM, Servelle M, Raiga JC, Lelièvre G, Tardieu JC. Lymphoedema of penis and scrotum: two observations. Ann Dermatol Venereol 1981; 108: 541-6.
Garaffa G, Christopher N, Ralph DJ. The management of genital lymphoedema. BJU Int 2008; 102: 480-4.
Morey AF, Meng MV, McAninch JW. Skin graft reconstruction of chronic genital lymphedema. Urology 1997; 50: 423-6.
Zacharakis E, Dudderidge T, Zacharakis E, Ioannidis E. Surgical repair of idiopathic scrotal elephantiasis. South Med J 2008; 101: 208-10.
Modolin M, Mitre AI, da Silva JC, et al. Surgical treatment of lymphedema of the penis and scrotum. Clinics 2006; 61: 289-94.