Reference : Deep infiltrating endometriosis is a determinant factor of cumulative pregnancy rate ...
Scientific journals : Article
Human health sciences : Reproductive medicine (gynecology, andrology, obstetrics)
http://hdl.handle.net/2268/112543
Deep infiltrating endometriosis is a determinant factor of cumulative pregnancy rate after intracytoplasmic sperm injection/in vitro fertilization cycles in patients with endometriomas
English
Ballester, M. [ > > ]
Oppenheimer, A. [ > > ]
Mathieu d'Argent, E. [ > > ]
Touboul, C. [ > > ]
Antoine, J. M. [ > > ]
NISOLLE, Michelle mailto [Centre Hospitalier Universitaire de Liège - CHU > > Gynécologie-Obstétrique CHR >]
Daraî, E. [ > > ]
2012
Fertility and Sterility
Elsevier
97
2
Yes (verified by ORBi)
International
0015-0282
1556-5653
New York
NY
[en] Cumulative pregnancy rate, ; deep infiltrating endometriosis ; endometriomas ; IVF
[en] Objective: To evaluate the cumulative pregnancy rate (CPR) per patient after in vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI) cycles in patients with endometriomas and to evaluate the determinant factors of CPR per patient. Design: Retrospective study from January 2007 to October 2008. Setting: Tertiary care university hospital.
Patient(s): 103 patients who had undergone IVF treatment, comprising isolated endometriomas (n 1⁄4 30) and endometriomas with associated deep infiltrating endometriosis (DIE) (n 1⁄4 73). Intervention(s): None. Main Outcome Measure(s): Clinical pregnancy rate after IVF-ICSI cycle.
Result(s): Thetotalnumberofcycleswas162,andthemediannumberofcyclesperpatientwas1(1to5).Fifty-eightwomen(56.3%)becamepregnant. The total number of endometriomas and size of the largest endometrioma and bilateral endometriomas had no impact on the CPR per patient. Using multivariable analysis, the associated DIE and antimu€llerian hormone serum level (%1 ng/mL) were independent factors associated with a decrease in the pregnancy rate per patient. Overall, the CPR per patient was 73.7%, and it increased until the third cycle with no benefit for additional cycles. The CPR per patient for women with isolated endometriomas and women with endometriomas and associated DIE was 82.5% and 69.4%, respectively. Conclusion(s): Associated DIE has a negative impact on assisted reproduction results in patients with endometriomas. Moreover, our data show that after three IVF-ICSI cycles the CPR per patient is not improved and that surgery should be considered
http://hdl.handle.net/2268/112543
10.1016/j.fertnstert.2011.11.022

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