| Reference : Analytical evaluation of the new Abbott Architect 25-OH vitamin D assay |
| Scientific journals : Article | |||
| Human health sciences : Laboratory medicine & medical technology | |||
| http://hdl.handle.net/2268/112310 | |||
| Analytical evaluation of the new Abbott Architect 25-OH vitamin D assay | |
| English | |
CAVALIER, Etienne [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >] | |
CARLISI, Ignazia [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >] | |
BEKAERT, Anne-Catherine [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >] | |
ROUSSELLE, Olivier [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >] | |
Chapelle, Jean-Paul [Université de Liège - ULg > Département de pharmacie > Chimie médicale >] | |
| Souberbielle, J. C. [ > > ] | |
| 2012 | |
| Clinical Biochemistry | |
| Elsevier Science | |
| 45 | |
| 505-508 | |
| International | |
| 0009-9120 | |
| 1873-2933 | |
| Tarrytown | |
| NY | |
| [en] vitamin D ; analytical validation ; immunoassay | |
| [en] Objectives: Validation of the Architect 25-OH vitamin D assay.
Design and methods: Determination of repeatability, reproducibility, accuracy profile and 25(OH)-vitamin D2 recovery on native samples. Comparison with DiaSorin Liaison and RIA. Results and conclusion: Coefficients of variation: b6% (13.6 ng/mL) and 2.2% (78.1 ng/mL). Functional sensitivity: 5 ng/mL. Accuracy profile shows that the method is validated between 13.6 and 78.1 ng/mL. Recovery of 25(OH)D2: 75,8%( 95% CI: 61.9–89.7%). Good correlation with DiaSorin RIA and Liaison b50 ng/mL; above this threshold a systematic positive bias was observed. | |
| http://hdl.handle.net/2268/112310 |
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