Reference : Role of Biochemical Markers of Bone Turnover as Prognostic Indicator of Successful Osteo...
Scientific journals : Article
Human health sciences : Rheumatology
http://hdl.handle.net/2268/11093
Role of Biochemical Markers of Bone Turnover as Prognostic Indicator of Successful Osteoporosis Therapy
English
Reginster, Jean-Yves mailto [Université de Liège - ULg > Département des sciences de la santé publique > Epidémiologie et santé publique >]
Collette, Julien mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >]
Neuprez, Audrey mailto [Université de Liège - ULG > Département des Sicences de la Santé Publique > Epidémiologie et santé publique > >]
Zegels, Brigitte mailto [Université de Liège - ULg > Département des sciences de la santé publique > Epidémiologie et santé publique]
Deroisy, Rita mailto [Centre Hospitalier Universitaire de Liège - CHU > > Médecine de l'appareil locomoteur >]
Bruyère, Olivier mailto [Université de Liège - ULg > Département des sciences de la santé publique > Epidémiologie et santé publique >]
10-Feb-2008
BONE
42
832-836
Yes (verified by ORBi)
International
8756-3282
[en] Osteoporosis ; Monitoring ; Treatment ; Bone density ; Markers of bone turnover
[en] Most of the currently available anti-osteoporosis medications promptly and significantly influence the rate of bone turnover. Biochemical markers of bone turnover now provide a high sensitivity to change, allowing the detection of these bone turnover changes within a couple of weeks. Since the anti-fracture efficacy of inhibitors of bone resorption or stimulators of bone formation appears to be largely independent of baseline bone turnover, biochemical markers do not appear to play a significant role in the selection of one particular drug, for an individual patient. However, there are consistent data showing that short-term changes in biochemical markers of bone turnover may be significant predictors of future changes in bone mineral density or fracture reduction, hence suggesting that bone turnover markers play a significant role in the monitoring of anti-osteoporosis therapy.
http://hdl.handle.net/2268/11093
10.1016/j.bone.2008.01.021
http://www.elsevier.com/wps/find/journaldescription.cws_home/525233/description#description

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