Article (Scientific journals)
Functional neuroanatomy of the hypnotic state.
Faymonville, Marie-Elisabeth; Boly, Mélanie; Laureys, Steven
2006In Journal of Physiology - Paris, 99 (4-6), p. 463-9
Peer Reviewed verified by ORBi
 

Files


Full Text
Faymonville J Physiology 2006.pdf
Publisher postprint (758.94 kB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Brain/anatomy & histology/physiology; Humans; Hypnosis; Magnetic Resonance Imaging; Pain/psychology; Perception/physiology
Abstract :
[en] The neural mechanisms underlying hypnosis and especially the modulation of pain perception by hypnosis remain obscure. Using PET we first described the distribution of regional cerebral blood flow during the hypnotic state. Hypnosis relied on revivification of pleasant autobiographical memories and was compared to imaging autobiographical material in "normal alertness". The hypnotic state was related to the activation of a widespread set of cortical areas involving occipital, parietal, precentral, premotor, and ventrolateral prefrontal and anterior cingulate cortices. This pattern of activation shares some similarities with mental imagery, from which it mainly differs by the relative deactivation of precuneus. Second, we looked at the anti-nociceptive effects of hypnosis. Compared to the resting state, hypnosis reduced pain perception by approximately 50%. The hypnosis-induced reduction of affective and sensory responses to noxious thermal stimulation were modulated by the activity in the midcingulate cortex (area 24a'). Finally, we assessed changes in cerebral functional connectivity related to hypnosis. Compared to normal alertness (i.e., rest and mental imagery), the hypnotic state, significantly enhanced the functional modulation between midcingulate cortex and a large neural network involved in sensory, affective, cognitive and behavioral aspects of nociception. These findings show that not only pharmacological but also psychological strategies for pain control can modulate the cerebral network involved in noxious perception.
Disciplines :
Neurosciences & behavior
Neurology
Author, co-author :
Faymonville, Marie-Elisabeth ;  Centre Hospitalier Universitaire de Liège - CHU > Anesthésie et réanimation
Boly, Mélanie ;  Université de Liège - ULiège > Département des sciences cliniques > Neurologie
Laureys, Steven  ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Language :
English
Title :
Functional neuroanatomy of the hypnotic state.
Publication date :
2006
Journal title :
Journal of Physiology - Paris
ISSN :
0928-4257
Publisher :
Elsevier Science, Paris, France
Volume :
99
Issue :
4-6
Pages :
463-9
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 31 January 2012

Statistics


Number of views
99 (7 by ULiège)
Number of downloads
4 (4 by ULiège)

Scopus citations®
 
161
Scopus citations®
without self-citations
154
OpenCitations
 
111

Bibliography


Similar publications



Contact ORBi