Reference : Les prélèvements microbiologiques ont-ils encore une place dans le diagnostic de pneu...
Scientific journals : Article
Human health sciences : Anesthesia & intensive care
http://hdl.handle.net/2268/110192
Les prélèvements microbiologiques ont-ils encore une place dans le diagnostic de pneumopathie acquise sous ventilation mécanique ?
English
LAYIOS, Nathalie mailto [Centre Hospitalier Universitaire de Liège - CHU > > Soins intensifs >]
DAMAS, Pierre mailto [Centre Hospitalier Universitaire de Liège - CHU > > Soins intensifs >]
2012
Réanimation
Elsevier
21
3-8
Yes (verified by ORBi)
International
1624-0693
1951-6959
Paris
France
[en] Diagnosis of ventilator-associated pneumonia
(VAP) is based on non-specific clinical signs. Several
indicators have been tested in order to improve the accuracy
of VAP diagnosis. The quantification of clinical parameters
by using the clinical pulmonary infection score (CPIS),
however, failed to improve the specificity of the diagnosis.
This was the same for all the biomarkers tested either in
the serum (procalcitonin, C-reactive protein) or in the bronchoalveolar
lavage (BAL) fluid [soluble triggering receptor
expressed on myeloid cells 1 (sTREM 1), elastin fibers,
endotoxin, pro-inflammatory cytokines, Clara cell protein
10]. The microscopic examination of endotracheal samples
alone, especially of the BAL fluid, may provide useful
information for the detection of infected cells. Thus, microbiology
is still needed.
http://hdl.handle.net/2268/110192

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