Reference : Left atrial function and remodelling in aortic stenosis.
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
Human health sciences : General & internal medicine
http://hdl.handle.net/2268/109731
Left atrial function and remodelling in aortic stenosis.
English
O'Connor, K. [> >]
Magne, Julien mailto [Université de Liège - ULg > Département des sciences cliniques > Cardiologie - Pathologie spéciale et réhabilitation >]
Rosca, M. [> >]
Pierard, Luc mailto [Université de Liège - ULg > Département des sciences cliniques > Cardiologie - Pathologie spéciale et réhabilitation >]
Lancellotti, Patrizio mailto [Université de Liège - ULg > Département des sciences cliniques > Imagerie cardiaque fonctionnelle par échographie >]
Apr-2011
European Journal of Echocardiography
Harcourt Publishers Limited
12
4
299-305
Yes (verified by ORBi)
International
1525-2167
1532-2114
[en] Left atrial phasic volume ; Left atrial function ; Strain rate ; Aortic stenosis ; Atrial function ; Doppler imagin
[en] AIMS: The present study sought to determine the relationship between left atrial (LA) volume (structural changes) and LA function as assessed by strain rate imaging in patients with aortic stenosis (AS).
<br />METHODS AND RESULTS: The study consisted of a total of 64 consecutive patients with severe AS (<1 cm²) and 20 healthy control subjects. The phasic LA volumes and function (tissue Doppler-derived strain) were assessed in all patients. As compared with healthy controls, all strain-derived parameters of LA function were reduced in patients with AS. Conversely, only indexed LA passive volume (increased) (7.6 ± 3.8 vs. 10.5 ± 5.1 ml/m², P= 0.02) and LA active fraction (decreased) (43 ± 6.7 vs. 31 ± 13.3%, P< 0.001) (volume-based parameters) were significantly different between AS and controls. In AS, LA volume-derived function parameters were poorly correlated with LA strain parameters. In fact, by multivariable analysis, no LA phasic strain parameters emerged as independently associated with LA phasic volume parameters.
<br />CONCLUSIONS: In AS, changes in LA function did not parallel changes in LA size. Furthermore, the increase in LA volume does not necessarily reflect the presence of intrinsic LA dysfunction
Service de Cardiologie
Researchers ; Professionals
http://hdl.handle.net/2268/109731
also: http://hdl.handle.net/2268/140771
10.1093/ejechocard/jer006
http://ehjcimaging.oxfordjournals.org/content/12/4/299.full.pdf+html

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