Reference : Comparison of the Full Outline of UnResponsiveness and Glasgow Liege Scale/Glasgow Co...
Scientific journals : Article
Human health sciences : Neurology
http://hdl.handle.net/2268/109001
Comparison of the Full Outline of UnResponsiveness and Glasgow Liege Scale/Glasgow Coma Scale in an Intensive Care Unit Population.
English
Bruno, Marie-Aurélie mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
LEDOUX, Didier mailto [Centre Hospitalier Universitaire de Liège - CHU > > Soins intensifs]
LAMBERMONT, Bernard mailto [Centre Hospitalier Universitaire de Liège - CHU > > Frais communs médecine]
DAMAS, François mailto [Centre Hospitalier Universitaire de Liège - CHU > > Anesthésie et réanimation]
Schnakers, Caroline mailto [coma science group, centre de recherches du cyclotron ULg & service de neurologie CHU de Liège > > > >]
Vanhaudenhuyse, Audrey mailto [coma science group, centre de recherches du cyclotron ULg & service de neurologie CHU de Liège > > > >]
Gosseries, Olivia mailto [coma science group, centre de recherches du cyclotron ULg & service de neurologie CHU de Liège > > > >]
Laureys, Steven mailto [coma science group, centre de recherches du cyclotron ULg & service de neurologie CHU de Liège > > > >]
2011
Neurocritical Care
Springer Science & Business Media B.V.
15
3
447-53
Yes (verified by ORBi)
1541-6933
1556-0961
[en] BACKGROUND: The Full Outline of UnResponsiveness (FOUR) has been proposed as an alternative for the Glasgow Coma Scale (GCS)/Glasgow Liege Scale (GLS) in the evaluation of consciousness in severely brain-damaged patients. We compared the FOUR and GLS/GCS in intensive care unit patients who were admitted in a comatose state. METHODS: FOUR and GLS evaluations were performed in randomized order in 176 acutely (<1 month) brain-damaged patients. GLS scores were transformed in GCS scores by removing the GLS brainstem component. Inter-rater agreement was assessed in 20% of the studied population (N = 35). A logistic regression analysis adjusted for age, and etiology was performed to assess the link between the studied scores and the outcome 3 months after injury (N = 136). RESULTS: GLS/GCS verbal component was scored 1 in 146 patients, among these 131 were intubated. We found that the inter-rater reliability was good for the FOUR score, the GLS/GCS. FOUR, GLS/GCS total scores predicted functional outcome with and without adjustment for age and etiology. 71 patients were considered as being in a vegetative/unresponsive state based on the GLS/GCS. The FOUR score identified 8 of these 71 patients as being minimally conscious given that these patients showed visual pursuit. CONCLUSIONS: The FOUR score is a valid tool with good inter-rater reliability that is comparable to the GLS/GCS in predicting outcome. It offers the advantage to be performable in intubated patients and to identify non-verbal signs of consciousness by assessing visual pursuit, and hence minimal signs of consciousness (11% in this study), not assessed by GLS/GCS scales.
http://hdl.handle.net/2268/109001
10.1007/s12028-011-9547-2

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