Reference : Transcranial magnetic stimulation-evoked EEG/cortical potentials in physiological and pa...
Scientific journals : Article
Human health sciences : Neurology
http://hdl.handle.net/2268/108997
Transcranial magnetic stimulation-evoked EEG/cortical potentials in physiological and pathological aging.
English
Casarotto, Silvia mailto [> > > >]
Maatta, Sara mailto [> > > >]
Herukka, Sanna-Kaisa mailto [> > > >]
Pigorini, Andrea mailto [> > > >]
Napolitani, Martino mailto [> > > >]
Gosseries, Olivia mailto [Université de Liège - ULg > Coma Science Group, Centre de Recherches du Cyclotron ULg & service de neurologie CHU de Liège > > >]
Niskanen, Eini mailto [> > > >]
Kononen, Mervi mailto [> > > >]
Mervaala, Esa mailto [> > > >]
Rosanova, Mario mailto [> > > >]
Soininen, Hilkka mailto [> > > >]
Massimini, Marcello mailto [> > > >]
2011
Neuroreport
Lippincott Williams & Wilkins
22
12
592-7
Yes (verified by ORBi)
0959-4965
1473-558X
London
United Kingdom
[en] Adult ; Aged ; Aging/physiology ; Alzheimer Disease/physiopathology ; Brain/physiology/physiopathology ; Electroencephalography ; Female ; Humans ; Male ; Transcranial Magnetic Stimulation
[en] The frontal cortex undergoes macrostructural and microstructural changes across the lifespan. These changes can be entirely physiological, such as the ones occurring in elderly individuals who are cognitively intact, or pathological, such as the ones occurring in patients with Alzheimer's disease. Here, we use simultaneous electroencephalography (EEG) and transcranial magnetic stimulation (TMS) to study how the excitability of the frontal cortex changes during healthy and pathological aging. Hence, we compared the TMS-evoked EEG potentials collected in healthy elderly individuals with the ones collected in healthy young individuals, and in patients with Alzheimer's disease. We have shown that the EEG response to TMS of the left superior frontal cortex is not affected by physiological aging but is markedly altered by cognitive impairment.
http://hdl.handle.net/2268/108997
10.1097/WNR.0b013e328349433a

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