Article (Scientific journals)
Acido-basic properties of lipophilic substances: A surface potential approach
Caspers, J.; Goormaghtigh, E.; Ferreira, J. et al.
1983In Journal of Colloid and Interface Science, 91 (2), p. 546-551
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Abstract :
[en] A general procedure allowing the acido-basic properties of lipophilic compounds to be defined is described. Drugs are spread at the air-water interface and the surface potential is recorded at different pH values of the aqueous subphase. Comparison of this experimental parameter and the Gouy-Chapman theory prediction allows the calculation of the acid (or basic) dissociation constants and the surface charge density.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Caspers, J.
Goormaghtigh, E.
Ferreira, J.
Brasseur, Robert ;  Université de Liège - ULiège > Chimie et bio-industries > Centre de Bio. Fond. - Section de Biophysique moléc. numér.
Vandenbranden, M.
Ruysschaert, J. M.
Language :
English
Title :
Acido-basic properties of lipophilic substances: A surface potential approach
Publication date :
February 1983
Journal title :
Journal of Colloid and Interface Science
ISSN :
0021-9797
eISSN :
1095-7103
Publisher :
Academic Press, Orlando, United States - Florida
Volume :
91
Issue :
2
Pages :
546-551
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 20 January 2012

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