[en] A general procedure of evaluation of the lipid-drug association constant in monolayer is presented. Lipids are spread at the air-water interface and the drugs injected into the aqueous subphase. Association constant potential and predictions from the Gouy-Chapman theory. Several procedures of calculation are described.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Goormaghtigh, E.
Brasseur, Robert ; Université de Liège - ULiège > Chimie et bio-industries > Centre de Bio. Fond. - Section de Biophysique moléc. numér.
Vanderbranden, M.
Caspers, J.
Ruysschaert, J. M.
Language :
English
Title :
Evaluation of the lipid-drug association constant in model membranes: A monolayer approach
Caspers, Berliner, Ruysschaert, Jaffé (1974) Conformation of a copolypeptide at the air—water interface. Journal of Colloid and Interface Science 49:433.
Saraga, Thomas J. Colloid Interface Sci. 1974, 48:42.