Article (Scientific journals)
Traitement de la maladie de Parkinson en 2009.
MAERTENS DE NOORDHOUT, Alain
2009In Revue Médicale Suisse, 5 (214), p. 1650-5
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Keywords :
Antiparkinson Agents/administration & dosage/adverse effects; Deep Brain Stimulation/methods; Dopamine Agonists/administration & dosage/adverse effects; Drug Therapy, Combination; Dyskinesia, Drug-Induced/etiology; Humans; Levodopa/administration & dosage/adverse effects; Parkinson Disease/drug therapy/surgery/therapy; Primary Dysautonomias/drug therapy; Prognosis; Risk Factors
Abstract :
[en] The cause of Parkinson's disease remains unknown and no cure or prevention exists so far. Levodopa remains by far the most potent symptomatic therapy, but induces side-effects such as motor fluctuations and abnormal movements, which can somewhat be counterbalanced by optimizing levodopa plasma levels or acting at receptors level with long half-life dopamine agonists. In severe cases, functional surgery with deep brain stimulation can be offered. Some non-dopaminergic symptoms like dementia, freezing, postural instability or dysautonomia do not respond to dopaminergic drugs and need special care.
Disciplines :
Neurology
Author, co-author :
MAERTENS DE NOORDHOUT, Alain  ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie CHR
Language :
French
Title :
Traitement de la maladie de Parkinson en 2009.
Alternative titles :
[en] Management of Parkinson's disease in 2009
Publication date :
2009
Journal title :
Revue Médicale Suisse
ISSN :
1660-9379
Publisher :
Medecine et Hygiène, Switzerland
Volume :
5
Issue :
214
Pages :
1650-5
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 18 January 2012

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