Reference : Development of the Crohn's disease digestive damage score, the Lemann score.
Scientific journals : Article
Human health sciences : Gastroenterology & hepatology
http://hdl.handle.net/2268/108254
Development of the Crohn's disease digestive damage score, the Lemann score.
English
Pariente, Benjamin [> > > >]
Cosnes, Jacques [> > > >]
Danese, Silvio [> > > >]
Sandborn, William J [> > > >]
Lewin, Maite [> > > >]
Fletcher, Joel G [> > > >]
Chowers, Yehuda [> > > >]
D'Haens, Geert [> > > >]
Feagan, Brian G [> > > >]
Hibi, Toshifumi [> > > >]
Hommes, Daniel W [> > > >]
Irvine, E Jan [> > > >]
Kamm, Michael A [> > > >]
Loftus, Edward V Jr [> > > >]
Louis, Edouard mailto [Centre Hospitalier Universitaire de Liège - CHU > > Gastro-Entérologie-Hépatologie >]
Michetti, Pierre [> > > >]
Munkholm, Pia [> > > >]
Oresland, Tom [> > > >]
Panes, Julian [> > > >]
Peyrin-Biroulet, Laurent [> > > >]
Reinisch, Walter [> > > >]
Sands, Bruce E [> > > >]
Schoelmerich, Juergen [> > > >]
Schreiber, Stefan [> > > >]
Tilg, Herbert [> > > >]
Travis, Simon [> > > >]
van Assche, Gert [> > > >]
Vecchi, Maurizio [> > > >]
Mary, Jean*-Yves [> > > >]
Colombel, Jean*-Frederic [> > > >]
Lemann, Marc [> > > >]
2011
Inflammatory Bowel Diseases
Lippincott Williams & Wilkins
17
6
1415-22
Yes (verified by ORBi)
International
1078-0998
1536-4844
Hagerstown
MD
[en] Colon/pathology/radiography/ultrasonography ; Colonoscopy ; Crohn Disease/pathology/radiography/ultrasonography ; Disease Progression ; Humans ; Magnetic Resonance Imaging ; Severity of Illness Index ; Tomography, X-Ray Computed
[en] Crohn's disease (CD) is a chronic progressive destructive disease. Currently available instruments measure disease activity at a specific point in time. An instrument to measure cumulative structural damage to the bowel, which may predict long-term disability, is needed. The aim of this article is to outline the methods to develop an instrument that can measure cumulative bowel damage. The project is being conducted by the International Program to develop New Indexes in Crohn's disease (IPNIC) group. This instrument, called the Crohn's Disease Digestive Damage Score (the Lemann score), should take into account damage location, severity, extent, progression, and reversibility, as measured by diagnostic imaging modalities and the history of surgical resection. It should not be "diagnostic modality driven": for each lesion and location, a modality appropriate for the anatomic site (for example: computed tomography or magnetic resonance imaging enterography, and colonoscopy) will be used. A total of 24 centers from 15 countries will be involved in a cross-sectional study, which will include up to 240 patients with stratification according to disease location and duration. At least 120 additional patients will be included in the study to validate the score. The Lemann score is expected to be able to portray a patient's disease course on a double-axis graph, with time as the x-axis, bowel damage severity as the y-axis, and the slope of the line connecting data points as a measure of disease progression. This instrument could be used to assess the effect of various medical therapies on the progression of bowel damage.
http://hdl.handle.net/2268/108254
10.1002/ibd.21506
Copyright (c) 2010 Crohn's & Colitis Foundation of America, Inc.

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
2011-Development of the Crohn's disease...Lémann score-IBD-PostPE.pdfPublisher postprint218.71 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.