Reference : Coma and consciousness: Paradigms (re)framed by neuroimaging.
Scientific journals : Article
Human health sciences : Neurology
http://hdl.handle.net/2268/107661
Coma and consciousness: Paradigms (re)framed by neuroimaging.
English
Laureys, Steven mailto [Université de Liège - ULg > > Centre de recherches du cyclotron, Coma science group, service de neurologie > >]
Schiff, N. [> > > >]
2012
NeuroImage
Elsevier Science
Yes
International
1053-8119
1095-9572
Orlando
FL
[en] coma ; vegetative state ; minimally conscious state ; fMRI ; PET ; consciousness ; traumatic brain injury
[en] The past 15years has provided an unprecedented collection of discoveries that bear upon our scientific understanding of recovery of consciousness in the human brain following severe brain damage. Highlighted among these discoveries are unique demonstrations that patients with little or no behavioral evidence of conscious awareness may retain critical cognitive capacities and the first scientific demonstrations that some patients, with severely injured brains and very longstanding conditions of limited behavioral responsiveness, may nonetheless harbor latent capacities for significant recovery. Included among such capacities are particularly human functions of language and higher-level cognition that either spontaneously or through direct interventions may reemerge even at long time intervals or remain unrecognized. Collectively, these observations have reframed scientific inquiry and further led to important new insights into mechanisms underlying consciousness in the human brain. These studies support a model of consciousness as the emergent property of the collective behavior of widespread frontoparietal network connectivity modulated by specific forebrain circuit mechanisms. We here review these advances in measurement and the scientific and broader implications of this rapidly progressing field of research.
Centre de Recherches du Cyclotron - CRC
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
http://hdl.handle.net/2268/107661
10.1016/j.neuroimage.2011.12.041
Copyright (c) 2011. Published by Elsevier Inc.

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