ORBi: Ledinh H. - Results of kidney transplantation from controlled donors after cardio-circulatory death: a single center experience.

Reference : Results of kidney transplantation from controlled donors after cardio-circulatory death:...


	Document type :	Scientific journals : Article
	Discipline(s) :	Human health sciences : Urology & nephrology Human health sciences : Surgery Human health sciences : Anesthesia & intensive care
	To cite this reference:	http://hdl.handle.net/2268/107377

Title :	Results of kidney transplantation from controlled donors after cardio-circulatory death: a single center experience.
Language :	English
Author, co-author :	Ledinh, H. [> > > >]
	WEEKERS, Laurent [Centre Hospitalier Universitaire de Liège - CHU > > Néphrologie]
	BONVOISIN, Catherine [Centre Hospitalier Universitaire de Liège - CHU > > Néphrologie]
	Krzesinski, Jean-Marie [Université de Liège - ULg > Département des sciences cliniques > Néphrologie]
	MONARD, Josée [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation]
	DE ROOVER, Arnaud [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation]
	SQUIFFLET, Jean-Paul [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation]
	Meurisse, Michel [Université de Liège - ULg > Département des sciences cliniques > Chirurgicale abdominale]
	DETRY, Olivier [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation]
Publication date :	Feb-2012
Journal title :	Transplant International
Publisher :	Springer International
Volume :	25
Pages :	201-209
Audience :	International
ISSN :	0934-0874
e-ISSN :	1432-2277
City :	Heidelberg
Country :	Germany
Abstract :	[en] The aim of this study was to determine results of kidney transplantation (KT) from controlled donation after cardio-circulatory death (DCD). Primary end-points were graft and patient survival, and post-transplant complications. The influence of delayed graft function (DGF) on graft survival and DGF risk factors were analyzed as secondary end-points. This is a retrospective mono-center review of a consecutive series of 59 DCD-KT performed between 2005 and 2010. Overall graft survival was 96.6%, 94.6%, and 90.7% at 3 months, 1 and 3 years, respectively. Main cause of graft loss was patient's death with a functioning graft. No primary nonfunction grafts. Renal graft function was suboptimal at hospital discharge, but nearly normalized at 3 months. DGF was observed in 45.6% of all DCD-KT. DGF significantly increased postoperative length of hospitalization, but had no deleterious impact on graft function or survival. Donor body mass index >/=30 was the only donor factor that was found to significantly increase the risk of DGF (P < 0.05). Despite a higher rate of DGF, controlled DCD-KT offers a valuable contribution to the pool of deceased donor kidney grafts, with comparable mid-term results to those procured after brain death.
Permalink :	http://hdl.handle.net/2268/107377
DOI :	10.1111/j.1432-2277.2011.01402.x
Commentary :	Transplant International (c) Michel Meurisse.

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