Article (Scientific journals)
Correlation of phasic muscle strength and corticomotoneuron conduction time in multiple sclerosis.
van der Kamp, W.; MAERTENS DE NOORDHOUT, Alain; Thompson, P. D. et al.
1991In Annals of Neurology, 29 (1), p. 6-12
Peer Reviewed verified by ORBi
 

Files


Full Text
annals of neurology, 1991, 29.pdf
Publisher postprint (637.93 kB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Adult; Electromyography; Female; Hand/physiology; Humans; Magnetics; Male; Middle Aged; Motor Cortex/physiology; Motor Neurons/physiology; Multiple Sclerosis/physiopathology; Muscle Contraction/physiology; Muscles/physiology; Neural Conduction/physiology; Reflex, Stretch/physiology; Time Factors
Abstract :
[en] Central motor conduction times for the adductor pollicis muscle, the twitch force of that muscle to scalp magnetic motor cortex stimulation, and the maximum force of phasic voluntary contraction of the same muscle were measured in 15 patients with multiple sclerosis. Two tests of manual dexterity of the same hand also were studied: the Purdue pegboard test, and the maximal frequency of a scissors movement of the thumb and index finger. The patients had normal strength or minimal weakness of the intrinsic muscles of the hand on clinical examination. The mean central motor conduction times for the adductor pollicis muscle for the patients were longer than normal, the peak twitch force of the adductor pollicis muscle evoked by cortical stimulation and the maximum force of a phasic voluntary contraction of the adductor pollicis muscle were smaller than normal. There were strong correlations between all these measures. Central motor conduction time in the patients was inversely correlated with voluntary phasic force and the twitch force after cortical stimulation. That is, the longer the central motor conduction time, the weaker the force. Prolonged central motor conduction time is likely to be accompanied by conduction block in corticomotoneuron pathways. The correlation of central motor conduction time with voluntary phasic force and the twitch force most likely reflects the degree of conduction block and temporal dispersion rather than delay in conduction per se. These results indicate that objective assessments of phasic muscle strength may reveal correlations with central motor conduction time that are not evident on conventional clinical examination which assesses tonic muscle contraction strength.(ABSTRACT TRUNCATED AT 250 WORDS)
Disciplines :
Neurology
Author, co-author :
van der Kamp, W.
MAERTENS DE NOORDHOUT, Alain  ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie CHR
Thompson, P. D.
Rothwell, J. C.
Day, B. L.
Marsden, C. D.
Language :
English
Title :
Correlation of phasic muscle strength and corticomotoneuron conduction time in multiple sclerosis.
Publication date :
1991
Journal title :
Annals of Neurology
ISSN :
0364-5134
eISSN :
1531-8249
Publisher :
Wiley Liss, Inc., New York, United States - New York
Volume :
29
Issue :
1
Pages :
6-12
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 09 January 2012

Statistics


Number of views
49 (6 by ULiège)
Number of downloads
2 (1 by ULiège)

Scopus citations®
 
63
Scopus citations®
without self-citations
60
OpenCitations
 
47

Bibliography


Similar publications



Contact ORBi