ORBi: Fumal Arnaud - Motor and phosphene thresholds to transcranial magnetic stimuli: a reproducibility study

Reference : Motor and phosphene thresholds to transcranial magnetic stimuli: a reproducibility study


	Document type :	Scientific journals : Article
	Discipline(s) :	Human health sciences : Neurology Social & behavioral sciences, psychology : Neurosciences & behavior
	To cite this reference:	http://hdl.handle.net/2268/106738

Title :	Motor and phosphene thresholds to transcranial magnetic stimuli: a reproducibility study
Language :	English
Author, co-author :	Fumal, Arnaud [Centre Hospitalier Universitaire de Liège - CHU > > Neurologie CHR >]
	Bohotin, V. [> > > >]
	Vandenheede, Michel [> >]
	Seidel, Laurence [Université de Liège - ULg > Département des sciences de la santé publique > Informatique médicale et biostatistique >]
	Maertens De Noordhout, Alain [Centre Hospitalier Universitaire de Liège - CHU > > Neurologie CHR >]
	Schoenen, Jean [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Neuro-anatomie]
Publication date :	Dec-2002
Journal title :	Acta Neurologica Belgica
Publisher :	Acta Medica Belgica
Volume :	102
Issue/season :	4
Pages :	171-175
Audience :	International
ISSN :	0300-9009
City :	Brussels
Country :	Belgique
Keywords :	[en] transcranial magnetic stimulation ; rTMS ; motor threshold ; phosphene threshold - reproducibility
Abstract :	[en] OBJECTIVES: As repetitive transcranial magnetic stimulation (rTMS) is often applied on different days, it is of interest to know whether motor (MT) and phosphene (PT) thresholds are reproducible across time and whether the intensity determined on the first day can be used in subsequent sessions. METHODS: We studied MT and PT over 5 separate recordings in 10 healthy volunteers using a focal coil and a Magstim(Rapid stimulator. After the initial recording (session 1), the others (2 to 5) were performed respectively after 1 day, 7 days, 1 month and 4 months. RESULTS: Mean MT at rest were 65.30 +/- 5.54%, 65.7 +/- 7.18%, 60.4 +/- 4.27%, 61.8 +/- 4.34%, and 63 +/- 9.1% at sessions 1 to 5. Mean PT were 71.43 +/- 6.68%, 66.29 +/- 10.67%, 60.71 +/- 8.64%, 60.57 +/- 8.08%, and 68.71 +/- 15.48% at sessions 1 to 5. MT and PT were reproducible (ANOVA analysis), however, as shown by coefficients of variation, variability between the first 3 sessions exceeded 10% for MT in 3 subjects and in 4 subjects for PT. CONCLUSIONS: It seems preferable to determine thresholds and adapt output intensity of the stimulator at each rTMS session.
Permalink :	http://hdl.handle.net/2268/106738

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