Article (Scientific journals)
Applications de la stimulation magnetique corticale.
MAERTENS DE NOORDHOUT, Alain
1998In Neurophysiologie Clinique, 28 (1), p. 9-30
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Keywords :
Animals; Cerebral Cortex/physiology; Electromagnetic Fields; Humans; Magnetoencephalography; Motor Cortex/physiology
Abstract :
[en] In the last decade, a new electrophysiological tool has become available since the development of painless magnetic stimulators able to activate the primary motor cortex and the motor roots in conscious man. Therefore, it became possible to measure the conduction time within fast-conducting central motor pathways by substracting from the total latency of muscle responses elicited by cortical stimuli the conduction time in peripheral nerves. This technique proved sensitive enough to illustrate early abnormalities of central motor conduction in various neurological diseases such as multiple sclerosis, amyotrophic lateral sclerosis, cervical spondylotic myelopathy, degenerative ataxias or hereditary spastic paraplegias. When recorded early after stroke, motor evoked potentials are also a valuable tool to predict functional outcome. They can also illustrate subtle pathophysiological disturbances in diseases where there is no direct involvement of central motor pathways such as Parkinson's disease, dystonia or epilepsy. Magnetic cortical stimulation also offers unique opportunities to explore intracerebral inhibitory and excitatory circuits and mechanisms of brain plasticity. The recent development of rapid rate stimulators also enables functional studies of non-motor cerebral regions such as visual or frontal cortices. Moreover, rapid rate stimulation seems useful in the treatment of drug-resistant depression but the safety of this procedure, particularly with regard to the production of seizures or kindling, remains to be fully documented.
Disciplines :
Neurology
Author, co-author :
MAERTENS DE NOORDHOUT, Alain  ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie CHR
Language :
French
Title :
Applications de la stimulation magnetique corticale.
Alternative titles :
[en] Applications of cortical magnetic stimulation
Publication date :
1998
Journal title :
Neurophysiologie Clinique
ISSN :
0987-7053
eISSN :
1769-7131
Publisher :
Elsevier, Paris, France
Volume :
28
Issue :
1
Pages :
9-30
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 27 December 2011

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