Reference : Analytic assessment under ultraviolet light of actinic lentigines under bleaching tre...
Scientific journals : Article
Human health sciences : Dermatology
http://hdl.handle.net/2268/106366
Analytic assessment under ultraviolet light of actinic lentigines under bleaching treatment.
English
PIERARD, Gérald mailto [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
Seite, Sophie [> > > >]
Rougier, Andre [> > > >]
QUATRESOOZ, Pascale mailto [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
2011
Journal of Cosmetic Dermatology
Blackwell Publishing
10
2
104-9
Yes (verified by ORBi)
International
1473-2130
1473-2165
[en] Antioxidants/therapeutic use ; Bleaching Agents/therapeutic use ; Cosmetic Techniques ; Female ; Glycolates/therapeutic use ; Humans ; Image Enhancement/methods ; Keratolytic Agents/therapeutic use ; Lentigo/diagnosis/drug therapy/etiology ; Pyrones/therapeutic use ; Sunlight/adverse effects ; Ultraviolet Rays/diagnostic use
[en] BACKGROUND: Actinic (solar) lentigines are melanotic tumors frequently developed during photoaging on the dorsum of the hands. Bleaching (whitening) agents are commonly offered to fade their darker aspect. In general, regular colorimetric methods show poor sensitivity to disclose any bleaching effect. METHOD: The present randomized controlled study on 24 women was designed to objectively assess the clinical efficacy of a combination of bleaching agents on actinic lentigines. In the endeavor of improving sensitivity, the ultraviolet light-enhanced visualization (ULEV) method was used to derive analytical measurements of lentigo areas and darkness. The test product was a commercially available formulation associating glycolic acid, kojic acid, lipohydroxyacid, and a Vitreoscilla extract. The Analysis(R) Olympus and Adobe Photoshop(R) quantitative methods were applied to the ULEV pictures. RESULTS: Data indicated a rapid bleaching effect arising as early as after 1 month of daily applications. The effect progressively increased over 3 months of therapy. CONCLUSION: The presently described analytical method appears to be sensitive to document some bleaching effects on actinic lentigines.
http://hdl.handle.net/2268/106366
10.1111/j.1473-2165.2011.00551.x
(c) 2011 Wiley Periodicals, Inc.

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