Article (Scientific journals)
Placental proteins secreted in maternal circulation: useful indicators for both pregnancy diagnosis and embryonic mortality in bovine species
Moreira da Silva, F.; Melo de Sousa, Noelita; Figueiredo, J. R. et al.
2003In Revista Portuguesa de Zootecnia, 10 (1), p. 99-121
 

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Keywords :
Bovine; Pregnancy-associated glycoprotein; Placenta; Protein
Abstract :
[en] During the last decades, several research groups developed investigations in order to characterize proteins or glycoproteins synthesized by ruminant placenta. As result of these investigations, a large family of pregnancy-associated glycoproteins was identified in bovine ovine and caprine placenta. By using molecular biology techniques, it was demonstrated that they are members of the aspartic proteinase superfamily, in which they co-exist with pepsinogens, renin, cathepsin D and E, etc. Due to their secretion in large amounts by the trophoblastic binucleated cells, bovine PAGs are detectable in maternal circulation soon after implantation. In the present work, in addition to the physiological and biochemical characterization of bovine PAGs, it will be showed how the measurement of PAG concentrations in maternal blood is useful for both pregnancy confirmation and follow-up of the fetus-placental well-being. Available information related to other placental proteins will be also discussed.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Moreira da Silva, F.
Melo de Sousa, Noelita ;  Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction
Figueiredo, J. R.
Beckers, Jean-François  ;  Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction
Language :
Portuguese
Title :
Placental proteins secreted in maternal circulation: useful indicators for both pregnancy diagnosis and embryonic mortality in bovine species
Publication date :
2003
Journal title :
Revista Portuguesa de Zootecnia
ISSN :
0872-7090
Publisher :
Associação Portuguesa de Engenharia Zootécnica (APEZ), Évora, Portugal
Volume :
10
Issue :
1
Pages :
99-121
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since 26 December 2011

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