Reference : Le cas clinique du mois. L'histoire naturelle d'une obesite morbide: aller vers le di...
Scientific journals : Article
Human health sciences : Endocrinology, metabolism & nutrition
Human health sciences : Surgery
http://hdl.handle.net/2268/10619
Le cas clinique du mois. L'histoire naturelle d'une obesite morbide: aller vers le diabete de type 2 insulinorequerant et retour apres chirurgie bariatrique.
French
[en] Clinical case of the month. Natural history of morbid obesity: towards insulin-requiring type 2 diabetes and reversal after bariatric surgery
De Flines, Jenny mailto [Centre Hospitalier Universitaire de Liège - CHU > > Diabétologie,nutrition, maladies métaboliques >]
Letiexhe, Michel [Centre Hospitalier Universitaire de Liège - CHU > > Diabétologie,nutrition, maladies métaboliques >]
Desaive, Claude [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
Scheen, André mailto [Université de Liège - ULg > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale >]
2001
Revue Médicale de Liège
56
12
816-22
Yes (verified by ORBi)
0370-629X
Belgium
[en] Adult ; Diabetes Mellitus, Type 2/etiology ; Gastric Bypass ; Humans ; Insulin Resistance ; Middle Aged ; Obesity, Morbid/complications/pathology ; Risk Factors ; Treatment Outcome ; Weight Loss
[en] Morbid obesity is a crucial risk factor in the development of type 2 diabetes and is often associated with a metabolic syndrome closely linked to insulin resistance. This case report illustrates the natural history of morbid obesity, starting during the adolescence and ending with an extremely severe type 2 diabetes at the age of 40. Numerous attempts of weight loss with various medical approaches failed and diabetes mellitus rapidly became insulin-requiring in a context of extreme insulin resistance. Finally, the patient was submitted to a gastric bypass which resulted in a drastic weight loss over 50 kg during the year following surgery without any significant side-effects or complications. Type 2 diabetes almost disappeared and the classical markers of insulin resistance were markedly improved. This clinical case clearly demonstrates that successful management of obesity with bariatric surgery can reverse severe type 2 diabetes.
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/10619
http://www.rmlg.ulg.ac.be

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