ORBi: Croisier Florence - Mechanical testing of electrospun PCL fibers

Reference : Mechanical testing of electrospun PCL fibers


	Document type :	Scientific journals : Article
	Discipline(s) :	Physical, chemical, mathematical & earth Sciences : Chemistry Engineering, computing & technology : Materials science & engineering
	To cite this reference:	http://hdl.handle.net/2268/106054

Title :	Mechanical testing of electrospun PCL fibers
Language :	English
Author, co-author :	Croisier, Florence [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
	Duwez, Anne-Sophie [University of Liège (ULg) > Department of Chemistry > Nanochemistry and Molecular Systems (NANOCHEM) > >]
	Jérôme, Christine [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
	Léonard, A. F. [University of Liège (ULg) > Department of Applied Chemistry > Laboratory of Chemical Engineering > >]
	van der Werf, K. O. [MESA and Institute for NanotechnologyUniversity of Twente, The Netherlands > Department of Science and Technology > Nanobiophysics > >]
	Dijkstra, P. J. [Institute for Biomedical Technology, University of Twente, The Netherlands > Department of Science and Technology > Polymer Chemistry and Biomaterials > >]
	Bennink, M. L. [MESA and Institute for NanotechnologyUniversity of Twente, The Netherlands > Department of Science and Technology > Nanobiophysics > >]
Publication date :	Jan-2012
Journal title :	Acta Biomaterialia
Publisher :	Elsevier Science
Volume :	8
Issue/season :	1
Pages :	218-224
Audience :	International
ISSN :	1742-7061
City :	Oxford
Country :	United Kingdom
Keywords :	[en] nanostructured material ; nanofiber ; electrospinning
Abstract :	[en] Poly(ε-caprolactone) (PCL) fibers ranging from 250 to 700 nm in diameter were produced by electrospinning a polymer tetrahydrofuran/N,N-dimethylformamide solution. The mechanical properties of the fibrous scaffolds and individual fibers were measured by different methods. The Young’s moduli of the scaffolds were determined using macro-tensile testing equipment, whereas single fibers were mechanically tested using a nanoscale three-point bending method, based on atomic force microscopy and force spectroscopy analyses. The modulus obtained by tensile-testing eight different fiber scaffolds was 3.8 ± 0.8 MPa. Assuming that PCL fibers can be described by the bending model of isotropic materials, a Young’s modulus of 3.7 ± 0.7 GPa was determined for single fibers. The difference of three orders of magnitude observed in the moduli of fiber scaffolds vs. single fibers can be explained by the lacunar and random structure of the scaffolds.
Research units :	Center for Education and Research on Macromolecules (CERM)
Funders :	Fonds pour la formation à la Recherche dans l'Industrie et dans l'Agriculture (Communauté française de Belgique) - FRIA ; Politique Scientifique Fédérale (Belgique) = Belgian Federal Science Policy
Target :	Researchers
Permalink :	http://hdl.handle.net/2268/106054
DOI :	10.1016/j.actbio.2011.08.015
Other URL :	http://www.sciencedirect.com/science?_ob=MiamiImageURL&_cid=273258&_user=532038&_pii=S1742706111003680&_check=y&_origin=browse&_coverDate=31-Jan-2012&view=c&wchp=dGLbVlV-zSkzV&md5=f9fb619c9e94518fbc8c3ebacf5030da/1-s2.0-S1742706111003680-main.pdf

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