Article (Scientific journals)
A pauci-symptomatic case of documented Hantavirus (Puumala) infection in a patient under anti-TNF treatment.
Moutschen, Pierre; Bourhaba, Maryam; FRIPPIAT, Frédéric et al.
2011In Journal of Clinical Virology, 50 (3), p. 247-8
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Keywords :
Adolescent; Antibodies, Viral/blood; Crohn Disease/drug therapy; Hantavirus/immunology; Hantavirus Infections/diagnosis/pathology; Humans; Immunologic Factors/therapeutic use; Male; Serologic Tests; Tumor Necrosis Factor-alpha/antagonists & inhibitors
Abstract :
[en] We describe the case of an 18-yr-old male under anti-TNF treatment for Crohn's disease for more than 8 months. He developed fever and biological inflammatory syndrome without absolutely no accompanying sign or symptom or paraclinical abnormality despite extensive work-up performed in the context of his immunocompromised state. Symptoms disappeared after 10 days and a diagnosis of Puumala infection was made retrospectively on a serological basis. The case illustrates that anti-TNF treatment does not worsen the course of Puumala infection and could even be associated with a milder clinical picture.
Disciplines :
General & internal medicine
Author, co-author :
Moutschen, Pierre
Bourhaba, Maryam ;  Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
FRIPPIAT, Frédéric  ;  Centre Hospitalier Universitaire de Liège - CHU > Maladies infectieuses et médecine interne générale
GIOT, Jean-Baptiste ;  Centre Hospitalier Universitaire de Liège - CHU > Maladies infectieuses et médecine interne générale
MEURIS, Christelle ;  Centre Hospitalier Universitaire de Liège - CHU > Maladies infectieuses et médecine interne générale
Leonard, Philippe ;  Centre Hospitalier Universitaire de Liège - CHU > Maladies infectieuses et médecine interne générale
Moutschen, Michel  ;  Université de Liège - ULiège > Département des sciences cliniques > GIGA-R:Immunopath. - Maladies infect. et médec. inter. gén.
Language :
English
Title :
A pauci-symptomatic case of documented Hantavirus (Puumala) infection in a patient under anti-TNF treatment.
Publication date :
2011
Journal title :
Journal of Clinical Virology
ISSN :
1386-6532
eISSN :
1873-5967
Publisher :
Elsevier Science, Amsterdam, Netherlands
Volume :
50
Issue :
3
Pages :
247-8
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
Copyright (c) 2010 Elsevier B.V. All rights reserved.
Available on ORBi :
since 15 December 2011

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