Reference : A pauci-symptomatic case of documented Hantavirus (Puumala) infection in a patient un...
Scientific journals : Article
Human health sciences : General & internal medicine
http://hdl.handle.net/2268/105339
A pauci-symptomatic case of documented Hantavirus (Puumala) infection in a patient under anti-TNF treatment.
English
Moutschen, Pierre [> > > >]
Bourhaba, Maryam [Université de Liège - ULg > Département des sciences cliniques > Département des sciences cliniques]
FRIPPIAT, Frédéric mailto [Centre Hospitalier Universitaire de Liège - CHU > > Maladies infectieuses et médecine interne générale]
GIOT, Jean-Baptiste mailto [Centre Hospitalier Universitaire de Liège - CHU > > Maladies infectieuses et médecine interne générale]
MEURIS, Christelle mailto [Centre Hospitalier Universitaire de Liège - CHU > > Maladies infectieuses et médecine interne générale]
Leonard, Philippe mailto [Université de Liège - ULg > Ressources immobilières > ARI : Installations techniques : Service de proximité]
Moutschen, Michel mailto [Université de Liège - ULg > Département des sciences cliniques > GIGA-R:Immunopath. - Maladies infect. et médec. inter. gén.]
2011
Journal of Clinical Virology
Elsevier Science
50
3
247-8
Yes (verified by ORBi)
International
1386-6532
Amsterdam
The Netherlands
[en] Adolescent ; Antibodies, Viral/blood ; Crohn Disease/drug therapy ; Hantavirus/immunology ; Hantavirus Infections/diagnosis/pathology ; Humans ; Immunologic Factors/therapeutic use ; Male ; Serologic Tests ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
[en] We describe the case of an 18-yr-old male under anti-TNF treatment for Crohn's disease for more than 8 months. He developed fever and biological inflammatory syndrome without absolutely no accompanying sign or symptom or paraclinical abnormality despite extensive work-up performed in the context of his immunocompromised state. Symptoms disappeared after 10 days and a diagnosis of Puumala infection was made retrospectively on a serological basis. The case illustrates that anti-TNF treatment does not worsen the course of Puumala infection and could even be associated with a milder clinical picture.
http://hdl.handle.net/2268/105339
10.1016/j.jcv.2010.11.016
Copyright (c) 2010 Elsevier B.V. All rights reserved.

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