Reference : Diabete de type 2 et medicaments anti-inflammatoires: nouvelles perspectives therapeutiq...

	Document type :	Scientific journals : Article
	Discipline(s) :	Human health sciences : Pharmacy, pharmacology & toxicology Human health sciences : Endocrinology, metabolism & nutrition
	To cite this reference:	http://hdl.handle.net/2268/105085

Title :	Diabete de type 2 et medicaments anti-inflammatoires: nouvelles perspectives therapeutiques?
Language :	French
Alternative title :	[en] Type 2 diabetes and anti-inflammatory agents: new therapeutic prospects?
Author, co-author :	Esser, Nathalie [Université de Liège - ULg > > GIGA-R : Virologie - Immunologie]
	Paquot, Nicolas [Université de Liège - ULg > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine)]
	SCHEEN, André [Centre Hospitalier Universitaire de Liège - CHU > > Diabétologie,nutrition, maladies métaboliques]
Publication date :	2011
Journal title :	Revue Médicale Suisse
Volume :	7
Issue/season :	306
Pages :	1614-8, 1620
ISSN :	1660-9379
Country :	Switzerland
Keywords :	[en] Anti-Inflammatory Agents/therapeutic use ; Diabetes Mellitus, Type 2/therapy ; Humans ; Metabolic Syndrome X/drug therapy
Abstract :	[en] It is now well accepted that a chronic, low-grade inflammation is observed in abdominal obesity, insulin resistance and type 2 diabetes mellitus, and that pro-inflammatory cytokines and oxidative stress play a role in the pathogenesis of type 2 diabetes. These new findings raise the question of whether antiinflammatory strategies may have a place in the prevention and treatment of type 2 diabetes. This review article describes the results obtained in studies on patients with metabolic syndrome or type 2 diabetes aiming to test the metabolic effect of anti-inflammatory (salicylates, antagonists of interleukine-1, antagonists of tumor necrosis factor-alpha) and anti-oxydants (succinobucol) drugs.
Target :	Researchers ; Professionals
Permalink :	http://hdl.handle.net/2268/105085

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