Reference : The HTLV-1 Tax interactome.
Scientific journals : Article
Human health sciences : Oncology
http://hdl.handle.net/2268/10428
The HTLV-1 Tax interactome.
English
Boxus, Mathieu mailto [Université de Liège - ULg > Chimie et bio-industries > Centre de Bio. Fond. - Section de Biologie cell. et moléc. >]
Twizere, Jean-Claude mailto [Université de Liège - ULg > Chimie et bio-industries > Centre de Bio. Fond. - Section de Biologie cell. et moléc. >]
Legros, Sebastien [> > > >]
Dewulf, Jean-François [ > > ]
Kettmann, Richard mailto [Université de Liège - ULg > Chimie et bio-industries > Centre de Bio. Fond. - Section de Biologie cell. et moléc. >]
Willems, Luc mailto [Université de Liège - ULg > > GIGA-Research >]
2008
Retrovirology
BioMed Central
5
76
Yes (verified by ORBi)
International
1742-4690
London
United Kingdom
[en] Cell Cycle Proteins/genetics/metabolism ; Gene Products, tax/chemistry/genetics/metabolism ; HTLV-I Infections/metabolism/physiopathology/virology ; Host-Pathogen Interactions ; Human T-lymphotropic virus 1/chemistry/enzymology/genetics ; Humans ; Nuclear Pore Complex Proteins/genetics/metabolism ; Protein Binding ; Protein Structure, Tertiary ; Signal Transduction ; Transcription Factors/genetics/metabolism ; Transcriptional Activation
[en] The Tax1 oncoprotein encoded by Human T-lymphotropic virus type I is a major determinant of viral persistence and pathogenesis. Tax1 affects a wide variety of cellular signalling pathways leading to transcriptional activation, proliferation and ultimately transformation. To carry out these functions, Tax1 interacts with and modulates activity of a number of cellular proteins. In this review, we summarize the present knowledge of the Tax1 interactome and propose a rationale for the broad range of cellular proteins identified so far.
http://hdl.handle.net/2268/10428
10.1186/1742-4690-5-76

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
Boxus Interactome final.pdfPublisher postprint1.51 MBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.