Reference : Clinical implications of induced twin reduction in dairy cattle .
Scientific journals : Article
Life sciences : Veterinary medicine & animal health
http://hdl.handle.net/2268/103769
Clinical implications of induced twin reduction in dairy cattle .
English
Andreu-Vazquez, C. [ > > ]
Garcia-Ispierto, I. [ > > ]
Lopez-Bejar, M. [ > > ]
Melo de Sousa, Noelita mailto [Université de Liège - ULg > Département de sciences fonctionnelles > Physiologie de la reproduction >]
Beckers, Jean-François mailto [Université de Liège - ULg > Département de sciences fonctionnelles > Physiologie de la reproduction >]
Lopez-Gatius, F. [ > > ]
Aug-2011
Theriogenology
Elsevier
76
3
512-521
Yes (verified by ORBi)
International
0093-691X
New York
NY
[en] Twin reduction ; Amnion rupture ; progesterone ; pregnancy-associated glycoprotein ; dairy cattle
[en] Embryo reduction may prevent the negative effects of twinning in dairy cattle; however, the technique may carry an additional risk of pregnancy loss. The aim of this study was to evaluate the effect on pregnancy maintenance of embryo reduction by manual amnion rupture in unilateral and bilateral twin pregnant cows. A secondary objective was to examine the dynamics of endocrine factors following the treatment. On Day 35-41 of gestation 55 cows bearing two live twin embryos (28 bilateral, 27 unilateral) were randomly assigned to a twin reduction group (n = 27; cows fitted with a progesterone releasing intra-vaginal device for 21 days after manual amnion rupture) or control group (n = 28; untreated cows). Pregnancy loss before Day 90 was recorded in nine control and eleven twin reduction cows (32.1% vs 40.7%, respectively, p = 0.508). Logistic regression models indicated that laterality was the only variable significantly affecting pregnancy loss. The pregnancy loss risk was 8.7 times higher for unilateral than for bilateral twin pregnancies (59.3% vs 14.3%, respectively, P < 0.001) yet was similar in the unilateral control and unilateral twin reduction cows (62.3% vs 53.8%, respectively, P = 0.581). In contrast, four of 14 cows with bilateral twin pregnancies undergoing twin reduction lost their pregnancies while no losses were recorded in control cows with bilateral pregnancies (P = 0.049). A rise in plasma progesterone concentration was detected on the day following treatment in the twin reduction group and concentrations remained high within the first week of treatment. Plasma pregnancy-associated glycoprotein-1 (PAG-1) concentrations fell between Day 35-41 and Day 42-48, regardless of treatment. Our findings indicate that embryo reduction by manual amnion rupture did not carry an additional risk of pregnancy loss for unilateral twin pregnancies, whereas it increased the risk of pregnancy failure in bilateral twin pregnancies. However, benefits of preventing cows from delivering twins might also be considered when assessing the success of embryo reduction in bilateral twin pregnancies.
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/103769
10.1016/j.theriogenology.2011.03.003

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
AndreuVazquezC_Therio_2011.pdfPublisher postprint907.62 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.