|Reference : Replacement of goal-tracking by sign-tracking under reward uncertainty, and impairment b...|
|Scientific congresses and symposiums : Poster|
|Social & behavioral sciences, psychology : Neurosciences & behavior|
|Replacement of goal-tracking by sign-tracking under reward uncertainty, and impairment by dopamine antagonism in the rat|
|Anselme, Patrick [Université de Liège et University of Michigan (USA) > Département de Psychologie : cognition et comportement > Neuroscience comportementale et psychopharmacologie expér. > >]|
|Robinson, Mike J.F. [University of Michigan (USA) > Department of Psychology > > >]|
|Difeliceantonio, Alexandra G. [University of Michigan (USA) > Department of Psychology > > >]|
|Berridge, K. C. [University of Michigan (USA) > Department of Psychology > > >]|
|Society for Neuroscience|
|November 12-16 2011|
|[en] Hypothesis: uncertainty influences Pavlovian reward prediction by arousing incentive motivation for reward (or ‘wanting’), expressed as sign-tracking (ST) or goal-tracking (GT) responses in an autoshaping paradigm. Here we investigated the effect of 3 types of uncertainty: 1) reward probability (UCS occurred after CS+ under 50% probability), 2) uncertainty about reward magnitude (UCS was 1, 2, or 3 sucrose pellets), and 3) uncertainty resulting from a combination of both conditions. We also tested the effects of reversal learning (shift in reward probability from 100 to 50%) and systemic dopamine blockade under uncertainty (flupenthixol, i.p.) on acquisition of autoshaping.|
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