Reference : Bone Regeneration Using Porous Titanium Particles versus Bovine Hydroxyapatite: A Sinus ...
Scientific journals : Article
Human health sciences : Dentistry & oral medicine
http://hdl.handle.net/2268/103183
Bone Regeneration Using Porous Titanium Particles versus Bovine Hydroxyapatite: A Sinus Lift Study in Rabbits.
English
LAMBERT, France mailto [Centre Hospitalier Universitaire de Liège - CHU > > Médecine dentaire >]
LECLOUX, Geoffrey mailto [Centre Hospitalier Universitaire de Liège - CHU > > Médecine dentaire >]
Léonard, Angélique mailto [Université de Liège - ULg > Département de chimie appliquée > Génie chimique - Procédés et développement durable >]
Sourice, S. [> >]
Layrolle, P. [> >]
ROMPEN, Eric mailto [Centre Hospitalier Universitaire de Liège - CHU > > Médecine dentaire >]
2013
Clinical Implant Dentistry & Related Research
Blackwell Publishing
15
3
Yes (verified by ORBi)
International
1523-0899
1708-8208
[en] Aim: The first objective of this study was to qualitatively and quantitatively assess the bone formation process, particularly the long-term behavior and three-dimensional volume stability of subsinusal bone regeneration, using titanium (Ti) or bovine hydroxyapatite (BHA) granules, in a rabbit model. The second objective was to evaluate the effect of the hydration of the BHA particles with a therapeutic concentration of doxycycline solution on the osteogenesis and biomaterial resorption. Materials and Methods: Rabbits underwent a double sinus lift procedure using one of three materials: grade 1 porous Ti particles, BHA, or BHA hydrated with doxycycline solution (0.1 mg/ml) (BHATTC). Animals were sacrificed after 1 week, 5 weeks, or 6 months. Samples were analyzed using µCT and nondecalcified histology. Results: The materials used in each of the three groups allowed an optimal bone formation; bone quantities and densities were not statistically different between the three groups. At 6 months, more stable three-dimensional volume stability was found with Ti and BHATTC (p = .0033). At 5 weeks and 6 months, bone to material contact corroborating osteoconduction was significantly higher with BHA and BHATTC than with Ti (p < .0001). Conclusions and Clinical Implications: Even though the studied biomaterials displayed different architectures, they are relevant candidates for sinus lift bone augmentation prior to dental implants because they allow adequate three-dimensional stability and osteogenesis. However, to recommend the clinical use of Ti, both an observation on the drilling effects of Ti particles and clinical trials are needed.
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/103183

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
bone regeneration.pdfAuthor postprint3.5 MBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.