Reference : Cysteamine supplementation of in vitro maturation media: a review.
Scientific journals : Article
Life sciences : Biotechnology
Life sciences : Veterinary medicine & animal health
http://hdl.handle.net/2268/102989
Cysteamine supplementation of in vitro maturation media: a review.
English
Deleuze, Stefan mailto [> > > >]
Goudet, G. [Institut Scientifique de Recherche Agronomique - INRA > > > >]
2010
Reproduction in Domestic Animals
Blackwell Publishing
45
6
e476-82
Yes (verified by ORBi)
International
0936-6768
1439-0531
Berlin
Germany
[en] cysteamine ; oocyte ; equine
[en] Under in vitro culture conditions, oxidative modifications of cell components via increased reactive oxygen species (ROS) represent a major culture induced stress. Anti-oxidant systems such as glutathione (GSH) can attenuate the deleterious effects of oxidative stress by scavenging ROS. It has been suggested that GSH content in oocytes may serve as a reservoir protecting the zygote and the early embryos from oxidative damage before genomic activation and de novo GSH synthesis occur. Addition of low molecular weight compounds to culture media, such as cysteamine, can increase GSH levels by increasing cysteine uptake. Quite naturally, effects of supplementation of in vitro maturation (IVM) media with low molecular weight thiols have been studied in various species. This article reviews the use of cysteamine supplementation for IVM, its effects on maturation rates and further embryo development.
http://hdl.handle.net/2268/102989
10.1111/j.1439-0531.2010.01587.x
(c) 2010 Blackwell Verlag GmbH.

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
DeleuzeReviewCyst.pdfPublisher postprint336.01 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.