Reference : Lifetime absolute risk of hip and other osteoporotic fracture in Belgian women.
Scientific journals : Article
Business & economic sciences : Special economic topics (health, labor, transportation…)
Human health sciences : Public health, health care sciences & services
http://hdl.handle.net/2268/10283
Lifetime absolute risk of hip and other osteoporotic fracture in Belgian women.
English
Hiligsmann, Mickaël mailto [Université de Liège - ULg > HEC - Ecole de gestion de l'ULg > Economie industrielle >]
Bruyère, Olivier mailto [Université de Liège - ULg > Département des sciences de la santé publique > Epidémiologie et santé publique - Département des sciences de la santé publique >]
Ethgen, Olivier mailto [Université de Liège - ULg > Département des sciences de la santé publique > Santé publique : aspects spécifiques >]
Gathon, Henry-Jean mailto [Université de Liège - ULg > HEC - Ecole de gestion de l'ULg > Economie générale et gestion publique >]
Reginster, Jean-Yves mailto [Université de Liège - ULg > Département des sciences de la santé publique > Epidémiologie et santé publique >]
2008
BONE
43
6
991-4
Yes (verified by ORBi)
International
1873-2763
United States
[en] Aged ; Aged, 80 and over ; Belgium/epidemiology ; Female ; Hip Fractures/epidemiology/etiology ; Humans ; Middle Aged ; Osteoporosis/complications ; Risk Factors
[en] OBJECTIVES: To estimate the lifetime absolute risks of hip and other osteoporotic fracture in Belgian women aged 60 years and to examine the effect of changes in baseline population fracture risk and changes in life expectancy. MATERIALS AND METHODS: Estimates were performed using a Markov microsimulation model and were based on the incidence of first fracture as well as life expectancy. Baseline scenario included projected mortality rates and increasing fracture incidence by 1% per year. Alternative scenarios were performed on age, life expectancy and trends in fracture incidence. Lifetime fracture risk for osteoporotic population (T-score <or= -2.5) was also estimated. RESULTS: In the baseline scenario, lifetime absolute risks of hip fracture and of any major osteoporotic fracture (hip, clinical vertebral or wrist) were respectively 24.8% and 44.3%. Alternative scenarios showed that when assuming no change of age-specific fracture rates over time, these lifetime risks were 18.3% and 35.2%, while these values were 20.0% and 38.3% assuming no future mortality reductions. For osteoporotic women, these values were respectively 34.5% and 51.5%. CONCLUSION: We conclude that absolute lifetime fracture risks are substantial and that trends in fracture incidence and changes in life expectancy have a marked impact on absolute lifetime fracture risks.
http://hdl.handle.net/2268/10283
10.1016/j.bone.2008.08.119

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