ORBi: Druet Tom - Estimation of genetic parameters and genome scan for 15 semen characteristics traits of Holstein bulls.

Reference : Estimation of genetic parameters and genome scan for 15 semen characteristics traits of ...


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Animal production & animal husbandry Life sciences : Genetics & genetic processes
	To cite this reference:	http://hdl.handle.net/2268/1023

Title :	Estimation of genetic parameters and genome scan for 15 semen characteristics traits of Holstein bulls.
Language :	English
Author, co-author :	Druet, Tom [Institut Scientifique de Recherche Agronomique - INRA > Département de Génétique Animale > Station de Génétique Quantitative et Appliquée > >]
	Fritz, S. [> > > >]
	Sellem, E. [> > > >]
	Basso, B. [> > > >]
	Gerard, Olivier [Centre Hospitalier Universitaire de Liège - CHU > > Médecine de l'appareil locomoteur >]
	Salas-Cortes, L. [> > > >]
	Humblot, P. [> > > >]
	Druart, X. [> > > >]
	Eggen, A. [> > > >]
Publication date :	2009
Journal title :	Journal of Animal Breeding & Genetics
Publisher :	Blackwell Publishing
Volume :	126
Issue/season :	4
Pages :	269-77
Audience :	International
ISSN :	0931-2668
e-ISSN :	1439-0388
City :	Berlin
Country :	Germany
Keywords :	[en] Animals ; Cattle/classification/genetics ; Genome ; Genomics ; Heterozygote ; Male ; Phenotype ; Quantitative Trait Loci ; Semen
Abstract :	[en] A QTL detection experiment was performed in French dairy cattle to search for QTL related to male fertility. Ten families, involving a total of 515 bulls, were phenotyped for ejaculated volume and sperm concentration, number of spermatozoa, motility, velocity, percentage of motile spermatozoa after thawing and abnormal spermatozoa. A set of 148 microsatellite markers were used to realize a genome scan. First, genetic parameters were estimated for all traits. Semen production traits were found to have moderate heritabilities (from 0.15 to 0.30) while some of the semen quality traits such as motility had high heritabilities (close to 0.60). Genetic correlations among traits showed negative relationships between volume and concentration and between volume and most quality traits such as motility or abnormal sperm while correlations between concentration and these traits were rather favourable. Percentages of abnormal sperm were negatively related to quality traits, especially with motility and velocity of spermatozoa. Three QTL related to abnormal sperm frequencies were significant at p < 0.01. In total, 11 QTL (p < 0.05) were detected. However, the number of QTL detected was within the range of expected false positives. Because of the lack of power to find QTL in this design further analyses are required to confirm these QTL.
Permalink :	http://hdl.handle.net/2268/1023
DOI :	10.1111/j.1439-0388.2008.00788.x

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