Reference : A 2.5-Mb contig constructed from Angus, Longhorn and horned Hereford DNA spanning the po...
Scientific journals : Article
Life sciences : Agriculture & agronomy
Life sciences : Genetics & genetic processes
Life sciences : Zoology
http://hdl.handle.net/2268/101952
A 2.5-Mb contig constructed from Angus, Longhorn and horned Hereford DNA spanning the polled interval on bovine chromosome 1
English
Wunderlich, K. R. [> > > >]
Abbey, C. A. [> > > >]
Clayton, D. R. [> > > >]
Song, Y. [> > > >]
Schein, J. E. [> > > >]
Georges, Michel mailto [Université de Liège - ULg > Département de productions animales > Génomique animale >]
Coppieters, Wouter mailto [Université de Liège - ULg > Département de productions animales > Département de productions animales >]
Adelson, D. L. [> > > >]
Taylor, J. F. [> > > >]
Davis, S. L. [> > > >]
Gill, C. A. [> > > >]
Dec-2006
Animal Genetics
Blackwell Publishing
37
6
592-594
Yes (verified by ORBi)
International
0268-9146
1365-2052
Oxford
United Kingdom
[en] BAC contig ; bovine chromosome 1 ; polled ; STS ; Animals ; Cattle/genetics ; Chromosomes, Artificial, Bacterial ; Chromosomes, Mammalian ; Horns ; Contig Mapping/veterinary ; Humans ; Phenotype
[en] The polled locus has been mapped by genetic linkage analysis to the proximal region of bovine chromosome 1. As an intermediate step in our efforts to identify the polled locus and the underlying causative mutation for the polled phenotype, we have constructed a BAC-based physical map of the interval containing the polled locus. Clones containing genes and markers in the critical interval were isolated from the TAMBT (constructed from Angus and Longhorn genomic DNA) and CHORI-240 (constructed from horned Hereford genomic DNA) BAC libraries and ordered based on fingerprinting and the presence or absence of 80 STS markers. A single contig spanning 2.5 Mb was assembled. Comparison of the physical order of STSs to the corresponding region of human chromosome 21 revealed the same order of genes within the polled critical interval. This contig of overlapping BAC clones from horned and polled breeds is a useful resource for SNP discovery and characterization of positional candidate genes.
Researchers ; Professionals
http://hdl.handle.net/2268/101952
also: http://hdl.handle.net/2268/102129
10.1111/j.1365-2052.2006.01538.x

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