Reference : Measuring the extent of linkage disequilibrium in commercial pig populations
Scientific journals : Article
Life sciences : Agriculture & agronomy
Life sciences : Genetics & genetic processes
Life sciences : Zoology
http://hdl.handle.net/2268/101947
Measuring the extent of linkage disequilibrium in commercial pig populations
English
Harmegnies, N. [> > > >]
Farnir, Frédéric mailto [Université de Liège - ULg > Département de productions animales > Biostatistique, économie, sélection animale >]
DAVIN, Fabienne mailto [Centre Hospitalier Universitaire de Liège - CHU > > Anatomie pathologique]
Buys, N. [> > > >]
Georges, Michel mailto [Université de Liège - ULg > Département de productions animales > Génomique animale >]
Coppieters, Wouter mailto [Université de Liège - ULg > Département de productions animales > Département de productions animales >]
2006
Animal Genetics
Blackwell Publishing
37
3
225-231
Yes (verified by ORBi)
International
0268-9146
1365-2052
Oxford
United Kingdom
[en] Alleles ; Animals ; Chromosome Mapping ; Chromosomes, Mammalian ; effective population size ; Genotype ; linkage disequilibrium ; pigs ; Population Density ; Swine/genetics
[en] To evaluate the extent of linkage disequilibrium in domestic pigs, we genotyped 33 and 44 unrelated individuals from two commercial populations for 29 and five microsatellite markers located on chromosomes 15 and 2 respectively. A high proportion of marker pairs up to 40 cM apart exhibited significant linkage disequilibrium in both populations. Pair-wise r(2) values averaged between 0.15 and 0.50 (depending on chromosome and population) for markers < 1 cM apart and declined to values of 0.05 for more distant syntenic markers. Our results suggest that both populations underwent a bottleneck approximately 20 generations ago, which reduced the effective population size from thousands to < 200 animals.
Researchers ; Professionals
http://hdl.handle.net/2268/101947
also: http://hdl.handle.net/2268/102124
10.1111/j.1365-2052.2006.01438.x

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
20870833-1.pdfPublisher postprint334.51 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.