Reference : Adult bone marrow: which stem cells for cellular therapy protocols in neurodegenerative ...

	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Biochemistry, biophysics & molecular biology
	To cite this reference:	http://hdl.handle.net/2268/101776

Title :	Adult bone marrow: which stem cells for cellular therapy protocols in neurodegenerative disorders?
Language :	English
Author, co-author :	Wislet-Gendebien, Sabine [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine >]
	Laudet, Emerence [Université de Liège - ULg > > GIGA - Neurosciences >]
	Neirinckx, Virginie [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine >]
	Rogister, Bernard [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine >]
Publication date :	Nov-2011
Journal title :	Journal of Biomedicine & Biotechnology
Publisher :	Hindawi Publishing Corporation
Special issue title :	Toward Personalized Cell Therapies by Using Stem Cells
Audience :	International
ISSN :	1110-7243
e-ISSN :	1110-7251
Keywords :	[en] Neural crest ; stem cells ; regenerative
Abstract :	[en] The generation of neuronal cells from stem cells obtained from adult bone marrow is of significant clinical interest in order to design new cell therapy protocols for several neurological disorders. The recent identification in adult bone marrow of stem cells derived from the neural crests (NCSC) might explain the neuronal phenotypic plasticity shown by bone marrow cells. However, little information is available about the nature of these cells compared to mesenchymal stem cells (MSC). In this manuscript, we will review all information available concerning NCSC from adult tissues and their possible use in regenerative medecine. Moreover, as multiple recent studies showed the beneficial effect of bone marrow stromal cells in neurodegenerative diseases, we will discuss which stem cells isolated from adult bone marrow should be more suitable for cell replacement therapy.
Permalink :	http://hdl.handle.net/2268/101776

	File(s) associated to this reference
	Fulltext file(s): File Commentary Version Size Access Restricted access Hindawi 2011 Wislet-Gendebien .pdf Author preprint 1.19 MB Request copy

All documents in ORBi are protected by a user license.

 

© ULg Library Network |  Feedback |  ORBi legal notices

Dspace v1.5