Reference : Adult bone marrow: which stem cells for cellular therapy protocols in neurodegenerati...
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/2268/101776
Adult bone marrow: which stem cells for cellular therapy protocols in neurodegenerative disorders?
English
Wislet-Gendebien, Sabine mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine >]
Laudet, Emerence mailto [Université de Liège - ULg > > GIGA - Neurosciences >]
Neirinckx, Virginie [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine >]
Rogister, Bernard mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine >]
Nov-2011
Journal of Biomedicine & Biotechnology
Hindawi Publishing Corporation
Toward Personalized Cell Therapies by Using Stem Cells
Yes (verified by ORBi)
International
1110-7243
1110-7251
[en] Neural crest ; stem cells ; regenerative
[en] The generation of neuronal cells from stem cells obtained from adult bone marrow is of significant clinical interest in order to design new cell therapy protocols for several neurological disorders. The recent identification in adult bone marrow of stem cells derived from the neural crests (NCSC) might explain the neuronal phenotypic plasticity shown by bone marrow cells. However, little information is available about the nature of these cells compared to mesenchymal stem cells (MSC). In this manuscript, we will review all information available concerning NCSC from adult tissues and their possible use in regenerative medecine. Moreover, as multiple recent studies showed the beneficial effect of bone marrow stromal cells in neurodegenerative diseases, we will discuss which stem cells isolated from adult bone marrow should be more suitable for cell replacement therapy.
http://hdl.handle.net/2268/101776

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