ORBi: Paris Jérôme - Automated synthesis of [18F] FBEM for labeling of thiol containing compounds

Reference : Automated synthesis of [18F] FBEM for labeling of thiol containing compounds


	Document type :	Scientific congresses and symposiums : Poster
	Discipline(s) :	Physical, chemical, mathematical & earth Sciences : Chemistry
	To cite this reference:	http://hdl.handle.net/2268/101199

Title :	Automated synthesis of [18F] FBEM for labeling of thiol containing compounds
Language :	English
Author, co-author :	Paris, Jérôme [Université de Liège - ULg > > Centre de recherches du cyclotron >]
	Thonon, David [Université de Liège - ULg > > Centre de recherches du cyclotron >]
	Kaisin, Geoffroy [Université de Liège - ULg > > Centre de recherches du cyclotron >]
	Goblet, David [Université de Liège - ULg > > Centre de recherches du cyclotron >]
	Goukens, Eve [Université de Liège - ULg > Services administratifs généraux > Contrôle physique des radiations (SUCPR) >]
	Lacroix, Simon [> >]
	Luxen, André [Université de Liège - ULg > Département de chimie (sciences) > Chimie organique de synthèse >]
Publication date :	1-Sep-2011
Audience :	International
Event name :	19th International Symposium on Radiopharmaceutical Sciences (ISRS)
Event date :	28/08/2011 - 02/09/2011
Event organizer :	Society of Radiopharmaceutical Sciences
Event place (city) :	Amsterdam
Event country :	The Netherlands
Keywords :	[en] FBEM ; thiol ; radiosynthesis ; positron emission tomography
Abstract :	[en] [18F]FBEM, i.e. N-[2-(4-[18F]fluorobenzamido)ethyl]maleimide, is a useful synthon employed for the specific radiolabeling of thiol containing compounds, including peptides and proteins. The aim of the present work was to develop a fast, reproducible and fully automated synthesis of this compound in order to improve its availabilty as well as for obvious radioprotection matters.
Research units :	Centre de Recherches du Cyclotron - CRC
Funders :	Région wallonne : Direction générale des Technologies, de la Recherche et de l'Energie - DGTRE
Name of the research project :	Neofor
Target :	Researchers ; Professionals
Permalink :	http://hdl.handle.net/2268/101199
DOI :	10.1002/jlcr.1926
Other URL :	http://onlinelibrary.wiley.com/doi/10.1002/jlcr.1926/abstract

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