Reference : Actualites therapeutiques en oncologie: l'essor des therapeutiques ciblees
Scientific journals : Article
Human health sciences : Hematology
http://hdl.handle.net/2268/10060
Actualites therapeutiques en oncologie: l'essor des therapeutiques ciblees
French
[en] Current Therapeutic Progress in Oncology: The Development of Targeted Therapies
Gennigens, Christine mailto [Centre Hospitalier Universitaire de Liège - CHU > > Oncologie médicale >]
Sautois, Brieuc mailto [Centre Hospitalier Universitaire de Liège - CHU > > Oncologie médicale >]
Rorive, Andrée [Université de Liège - ULg > Département des sciences cliniques > Hématologie - Oncologie médicale]
Fillet, Georges mailto [Université de Liège - ULg > Département des sciences cliniques > Hématologie - Oncologie médicale]
Jerusalem, Guy mailto [Centre Hospitalier Universitaire de Liège - CHU > > Oncologie médicale >]
2007
Revue Médicale de Liège
62
5-6, May-Jun
391-8
Yes (verified by ORBi)
0370-629X
[en] Over the last decades, significant advances were make in basic research as concerns the malignant transformation of normal cells. As a result, new targets for treatment were identified. "Targeted therapies" indicates that treatments are directed against specific molecular targets that play a major role in the activation of cell division and in the growth and dissemination of tumors. In particular, targeted therapies were developed against epithelial growth factor receptors and angiogenesis. We can expect specifise therapies against many other targets in the near future. Several drugs have obtained a marketing license. Predictive factors for tumor response and long term outcome should be developed for a better selection of the patient population who will benefit from these treatments. New imaging techniques are under development in order to assess the molecular response to these new approaches.
http://hdl.handle.net/2268/10060

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