ORBi: Herens Christian - Translocation (2;3)(P21;Q26) as the Sole Anomaly in a Case of Primary Myelofibrosis

Reference : Translocation (2;3)(P21;Q26) as the Sole Anomaly in a Case of Primary Myelofibrosis


	Document type :	Scientific journals : Article
	Discipline(s) :	Human health sciences : Hematology
	To cite this reference:	http://hdl.handle.net/2268/10055

Title :	Translocation (2;3)(P21;Q26) as the Sole Anomaly in a Case of Primary Myelofibrosis
Language :	English
Author, co-author :	Herens, Christian [Centre Hospitalier Universitaire de Liège - CHU > > PLAN COS >]
	Hermanne, J. P. [> > > >]
	Tassin, Françoise [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie biologique et immuno hématologie >]
	Fassotte, M. F. [> > > >]
	Thiry, Albert [Centre Hospitalier Universitaire de Liège - CHU > > Anatomie pathologique >]
	Jamar, Michelle [Centre Hospitalier Universitaire de Liège - CHU > > HOPITAL DE JOUR ONCOLOGIQUE SART TILMAN >]
	Schaaf-Lafontaine, Nicole [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie biologique et immuno hématologie >]
	Fillet, Georges [Université de Liège - ULg > Département des sciences cliniques > Hématologie - Oncologie médicale]
	Koulischer, Lucien [Université de Liège - ULg > > Relations académiques et scientifiques (Médecine) >]
Publication date :	Apr-1999
Journal title :	Cancer Genetics & Cytogenetics
Publisher :	Elsevier Science
Volume :	110
Issue/season :	1
Pages :	62-4
ISSN :	0165-4608
Abstract :	[en] Translocation t(2p;3q) is a rare but recurrent finding in myeloid disorders. We present the first case of primary myelofibrosis with t(2;3)(p21;q26) as the sole chromosomal anomaly. The comparison with the 11 other previously published myeloid-associated t(2p;3q) cases confirms that this nonrandom translocation involves a pluripotent stem cell and is associated with a poor prognosis.
Permalink :	http://hdl.handle.net/2268/10055

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