Article (Scientific journals)
Etude clinique du mois. Radio-chimiotherapie et chimiotherapie adjuvante apres resection a visee curative du cancer du pancreas: resultats de l'etude randomisee ESPAC-1
Polus, Marc; Jerusalem, Guy; Sautois, Brieuc et al.
2002In Revue Médicale de Liège, 57 (2), p. 119-22
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Abstract :
[en] The prognosis of pancreatic adenocarcinoma remains poor, with a 5-year survival rate lower than 5%. Resection, the gold standard treatment, can be performed in less than 15% of patients. Following surgery, the median survival is 12 months for the most favourable cancer patients. Adjuvant treatment have attempted to improve results. However, chemotherapy, radiotherapy and multimodal treatments don't have demonstrated a clear advantage in controlled trials. We will discuss results of the current trials in this topic. The randomised trial of the European Study Group for Pancreatic Cancer (ESPAC) recently published in the Lancet revealed a potential benefit of adjuvant chemotherapy. A critical analysis of the publication showed, however, that definitive conclusions of this trial must be interpreted with caution.
Disciplines :
Hematology
Author, co-author :
Polus, Marc ;  Centre Hospitalier Universitaire de Liège - CHU > Gastro-Entérologie-Hépatologie
Jerusalem, Guy  ;  Centre Hospitalier Universitaire de Liège - CHU > Oncologie médicale
Sautois, Brieuc  ;  Centre Hospitalier Universitaire de Liège - CHU > Oncologie médicale
Silvestre, R. M.
Collette, M. Y.
Closon, M. T.
Fillet, Georges ;  Université de Liège - ULiège > Département des sciences cliniques > Hématologie - Oncologie médicale
Language :
French
Title :
Etude clinique du mois. Radio-chimiotherapie et chimiotherapie adjuvante apres resection a visee curative du cancer du pancreas: resultats de l'etude randomisee ESPAC-1
Alternative titles :
[en] Clinical Study of the Month. Adjuvant Radio-Chemotherapy and Chemotherapy Following Curative Resection of Pancreatic Cancer: Results of the Randomized Trial Espac-1
Publication date :
February 2002
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Belgium
Volume :
57
Issue :
2
Pages :
119-22
Peer reviewed :
Peer reviewed
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