Reference : Interplay between spontaneous and induced brain activity during human non-rapid eye move...
Scientific journals : Article
Human health sciences : Neurology
http://hdl.handle.net/2268/100257
Interplay between spontaneous and induced brain activity during human non-rapid eye movement sleep.
English
Dang Vu, Thien Thanh [Université de Liège - ULg > Département des sciences cliniques > Neurologie]
Bonjean, Maxime [> > > >]
Schabus, Manuel [> > > >]
Boly, Mélanie mailto [Université de Liège - ULg > Centre de Recherches du Cyclotron - Comascience group > Neurologie > >]
Darsaud, Annabelle [> > > >]
Desseilles, Martin mailto [Université de Liège - ULg > Département des sciences cliniques > Psychiatrie et psychologie médicale]
Degueldre, Christian mailto [Université de Liège - ULg > > Centre de recherches du cyclotron]
Balteau, Evelyne mailto [Université de Liège - ULg > > Centre de recherches du cyclotron]
Phillips, Christophe mailto [Université de Liège - ULg > > Centre de recherches du cyclotron]
Luxen, André mailto [Université de Liège - ULg > Département de chimie (sciences) > Chimie organique de synthèse]
Sejnowski, Terrence J [> > > >]
Maquet, Pierre mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
2011
Proceedings of the National Academy of Sciences of the United States of America
National Academy of Sciences
108
37
15438-43
Yes (verified by ORBi)
International
0027-8424
1091-6490
Washington
DC
[en] Adolescent ; Adult ; Audiometry, Pure-Tone ; Brain Mapping ; Electroencephalography ; Female ; Humans ; Male ; Sleep, REM/physiology ; Wakefulness/physiology ; Young Adult
[en] Humans are less responsive to the surrounding environment during sleep. However, the extent to which the human brain responds to external stimuli during sleep is uncertain. We used simultaneous EEG and functional MRI to characterize brain responses to tones during wakefulness and non-rapid eye movement (NREM) sleep. Sounds during wakefulness elicited responses in the thalamus and primary auditory cortex. These responses persisted in NREM sleep, except throughout spindles, during which they became less consistent. When sounds induced a K complex, activity in the auditory cortex was enhanced and responses in distant frontal areas were elicited, similar to the stereotypical pattern associated with slow oscillations. These data show that sound processing during NREM sleep is constrained by fundamental brain oscillatory modes (slow oscillations and spindles), which result in a complex interplay between spontaneous and induced brain activity. The distortion of sensory information at the thalamic level, especially during spindles, functionally isolates the cortex from the environment and might provide unique conditions favorable for off-line memory processing.
Centre de Recherches du Cyclotron - CRC
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS ; Fondation Médicale Reine Elisabeth ; Fonds Léon Fredericq
http://hdl.handle.net/2268/100257
also: http://hdl.handle.net/2268/104694
10.1073/pnas.1112503108
http://reflexions.ulg.ac.be/BruitSommeil

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