Reference : Stainless steel with robust anibacterial activiy based on a versatile and bio-inspire...
Scientific congresses and symposiums : Unpublished conference
Physical, chemical, mathematical & earth Sciences : Chemistry
Engineering, computing & technology : Materials science & engineering
http://hdl.handle.net/2268/100227
Stainless steel with robust anibacterial activiy based on a versatile and bio-inspired strategy
English
Faure, Emilie [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
Lecomte, Philippe mailto [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
Vreuls, Christelle mailto [University of Liège (ULg) > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire > > >]
Van de Weerdt, Cécile [University of Liège (ULg) > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire > > >]
Archambeau, Catherine [Artecelor Mittal > > > >]
Martial, Joseph mailto [Université de Liège - ULg > Département des sciences de la vie > Centre of Biomedical Integrative Genoproteomics (GIGA-R) > >]
Jérôme, Christine mailto [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
Duwez, Anne-Sophie mailto [University of Liège (ULg) > Department of Chemistry > Nanochemistry and Molecular Systems (NANOCHEM) > >]
Detrembleur, Christophe mailto [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
1-Sep-2011
No
No
International
242nd American Chemical Society (ACS) Meeting
28/08/2011 - 1/08/2011
Farmer R.
Morgan A.
Denver
USA
[en] biomimetic polymer
[en] The synthesis of a poly(methacrylamide) bearing 3,4-dihydroxyphenylalanine inspired from the chemical composition of mussel adhesives will be presented. This homopolymer is designed to insure a multilayer film growth by covalent coupling during the layer-by-layer building with a homopolymer containing amino groups. The film cross-linking is initiated by adequately controlling both the redox state of the polymer and the pH of the solutions. This cross-linking is evidenced by solid-state 13C NMR with the occurrence of a typical signal of imine, traducing the Schiff base formation during film growth. The same coupling reaction is implemented for grafting an antibacterial peptide, Nisin, on a stainless steel substrate. Antibacterial activity against Bacillus subtilis is preserved even after long immersion time, as the result of the peptide covalent anchoring on the surface. All the processing steps, including the synthesis of the polymers and the peptide grafting, are performed in aqueous solutions under mild conditions.
Center for Education and Research on Macromolecules (CERM)
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
Researchers
http://hdl.handle.net/2268/100227
This oral communication was presented by Emilie Faure

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