ORBi: Faure Emilie - Stainless steel with robust anibacterial activiy based on a versatile and bio-inspired strategy

Reference : Stainless steel with robust anibacterial activiy based on a versatile and bio-inspired s...


	Document type :	Scientific congresses and symposiums : Unpublished conference
	Discipline(s) :	Physical, chemical, mathematical & earth Sciences : Chemistry Engineering, computing & technology : Materials science & engineering
	To cite this reference:	http://hdl.handle.net/2268/100227

Title :	Stainless steel with robust anibacterial activiy based on a versatile and bio-inspired strategy
Language :	English
Author, co-author :	Faure, Emilie [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
	Lecomte, Philippe [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
	Vreuls, Christelle [University of Liège (ULg) > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire > > >]
	Van de Weerdt, Cécile [University of Liège (ULg) > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire > > >]
	Archambeau, Catherine [Artecelor Mittal > > > >]
	Martial, Joseph [Université de Liège - ULg > Département des sciences de la vie > Centre of Biomedical Integrative Genoproteomics (GIGA-R) > >]
	Jérôme, Christine [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
	Duwez, Anne-Sophie [University of Liège (ULg) > Department of Chemistry > Nanochemistry and Molecular Systems (NANOCHEM) > >]
	Detrembleur, Christophe [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
Publication date :	1-Sep-2011
On invitation :	No
Audience :	International
Event name :	242nd American Chemical Society (ACS) Meeting
Event date :	28/08/2011 - 1/08/2011
Event organizer :	Farmer R.
	Morgan A.
Event place (city) :	Denver
Event country :	USA
Keywords :	[en] biomimetic polymer
Abstract :	[en] The synthesis of a poly(methacrylamide) bearing 3,4-dihydroxyphenylalanine inspired from the chemical composition of mussel adhesives will be presented. This homopolymer is designed to insure a multilayer film growth by covalent coupling during the layer-by-layer building with a homopolymer containing amino groups. The film cross-linking is initiated by adequately controlling both the redox state of the polymer and the pH of the solutions. This cross-linking is evidenced by solid-state 13C NMR with the occurrence of a typical signal of imine, traducing the Schiff base formation during film growth. The same coupling reaction is implemented for grafting an antibacterial peptide, Nisin, on a stainless steel substrate. Antibacterial activity against Bacillus subtilis is preserved even after long immersion time, as the result of the peptide covalent anchoring on the surface. All the processing steps, including the synthesis of the polymers and the peptide grafting, are performed in aqueous solutions under mild conditions.
Research units :	Center for Education and Research on Macromolecules (CERM)
Funders :	Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
Target :	Researchers
Permalink :	http://hdl.handle.net/2268/100227
Commentary :	This oral communication was presented by Emilie Faure

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