http://hdl.handle.net/2268/96 Search this channel search http://orbi.ulg.ac.be/simple-search http://hdl.handle.net/2268/147489 Title: Prothèses articulaires et risque d'endocardite <br/> <br/>Author, co-author: MAINJOT, Amélie http://hdl.handle.net/2268/147488 Title: Maxillary reconstruction by parietal bone grafts before implant placement: a histomorphometrical study <br/> <br/>Author, co-author: MAINJOT, Amélie http://hdl.handle.net/2268/147487 Title: Residual Stress in Veneering Ceramic <br/> <br/>Author, co-author: MAINJOT, Amélie http://hdl.handle.net/2268/146625 Title: Augmentation osseuse sous-sinusienne : actualisation du concept du sinus lift. <br/> <br/>Author, co-author: Lambert, France; Lecloux, Geoffrey; Rompen, Eric <br/> <br/>Abstract: L’élévation du plancher sinusal est une technique permettant de placer des implants d’une longueur suffisante au niveau du maxillaire postérieur. Depuis qu’elle a été initialement décrite dans les années 80, cette technique a beaucoup évolué. A l’heure actuelle, on peut considérer cette approche comme prédictible, simple et réalisable au fauteuil sous anesthésie locale. Cet article vise d’abord à expliciter clairement le phénomène biologique du « sinus-lift », ensuite, de décrire le protocole chirurgical que nous appliquons à l’Université de Liège (Belgique) et de le confronter avec la littérature scientifique existante. http://hdl.handle.net/2268/145382 Title: One-piece zirconia implants : 18 months clinical outcomes. <br/> <br/>Author, co-author: VANHOUTTE, Vanessa; LAMBERT, France; ROMPEN, Eric <br/> <br/>Abstract: Purpose : The aim of the present study was to evaluate prospectively the clinical outcomes of a prototype one-piece zirconia implants after a -18 month follow-up. Material and methods : 20 prototype one-piece zirconia implants were placed and immediately restored with provisional protheses. A flapless or a minimally invasive approach was used for every implant placement. Bone levels were recorded at baseline and -1 year. Surgical, biological and prosthetic complications were also assessed. Results : The study included 15 patients. Most of the implants (90%) were placed at the anterior maxilla. Six of the implant sites were previously augmented with autogenous bone block grafts, 8 were managed with socket preservation techniques, 3 implants were immediatly placed after extraction and one implant was placed simultanously with a guided bone regeneration. Insertion torque (> 30N/cm2) was reached for all implants. The implant survival and success rates reached respectively 100% and 95%. One implant abutment fractured at placement because of an excessive insertion torque (> 50 N/cm2). No further complication occurred. Conclusion : From the preliminary results of this prospective clinical study, one-piece zirconia implants seem to success after 1 year despite they were often placed in critical clinical situtations (bone augmentations) and immediately restored. Further follow-up is needed to evaluate the long-term outcomes. http://hdl.handle.net/2268/145380 Title: “Pluridisciplinary approach for the treatment of aggressive periodontitis.” <br/> <br/>Author, co-author: LAMBERT, France http://hdl.handle.net/2268/145377 Title: Patient morbidity after socket preservation using a connective tissue graft versus a bilayer collagen matrix: Preliminary results of a comparative Randomized Control Trial. <br/> <br/>Author, co-author: FERNANDEZ AYORA, Alberto; VANHOUTTE, Vanessa; LECLOUX, Geoffrey; ROMPEN, Eric; LAMBERT, France <br/> <br/>Abstract: INTRODUCTION AND AIM: The present randomized controlled trial compared socket preservation procedures using bovine hydroxyapatite (Bio-Oss®, Geistlich, Switzerland) covered with a connective tissue graft (CT) versus a bilayer collagen membrane (CM) (Mucograft®, Geistlich, Switzerland), placed from buccal to palatal in split-thickness pouches in order to seal the extraction site and to potentially thicken the buccal mucosa. The aim of this present abstract was to evaluate post-operative complications and patient-centered outcomes of the two independent surgical protocols. METHODS: This randomized controlled trial included 26 patients (16 female, 10 male) aged from 20 to 69 years (mean: 42.6, SD: 12). 26 teeth were extracted atraumatically and the 2 distinct surgical protocols were applied randomly. Patients filled out a VAS form 1 week after the surgery to evaluate their level of discomfort and post-operative pain. Drug intakes as well as complications were also recorded. RESULTS: No statistical significant differences were found between the 2 groups in terms of post-operative complications (bleeding) and post-operative pain. The consumption of painkillers after the surgery decreased over time but was similar in the two groups. CONCLUSION: According to the preliminary results of the present RCT, none of both protocols seemed to induce significant post-operative pain and discomfort. There was no difference between the two procedures regarding post-operative complications and patient centered outcomes. http://hdl.handle.net/2268/145376 Title: Description of a ‘soft tissue friendly’ protocol for immediate loading in the esthetic zone: 1 year result of 13 consecutive patients <br/> <br/>Author, co-author: COMPEYRON, Yoann; LECLOUX, Geoffrey; ROMPEN, Eric; LEGROS, Caroline; LAMBERT, France <br/> <br/>Abstract: Objectives: Repeted abutment connection and disconnections compromize the connective and epithelial sealing around implant components, leading to peri-implant bone remodeling (Abrahamsson, 1997). Placing the definitive abutment at the time of implant placement might be a treatment option to minimize this biological rupture. The aim of this study was to evaluate the effectiveness of pre-shaped zirconium abutments for immediate implant loading in the anterior maxilla. Materials and methods: A total of 13 patients needing the placement of one or several implant in the esthetic zone were treated with Regular Crossfit Bone Level (Straumann) implants. Implants were placed and immediately restored with a pre-shaped zirconium abutments and provisional resin crowns if the primary stability reached at least 20 N/cm2. Implant survival rate, biological and prosthodontic complications as well as peri-implant tissue status (papilla index) were recorded during a follow-up period of 1 year. Results: A total of 14 implants (8 incisors, 1 canines, 5 premolars) placed in 11 patients (4 men / 7 women) aged from 22 to 60 years old (48,5 +/- 11,5) could be assessed for the entire follow-up period. 2 patients dropped out. All implants reached an adequate primary stability (> 20N/cm2) to perform an immediate implant restoration. Straight pre-shaped Zirconium abutment was used in each case. Six implants were placed in socket preservation sites and five implants were placed simultaneously with a GBR. After a follow-up period of 1 year, all implants fulfilled survival criteria for dental implants with regard to osteointegration, including the absence of peri-implant radiolucency, implant mobility, suppuration, and pain. One abutment screw loosening was observed during the provisional period and no abutment fracture occurred. Definitive full ceramic-cemented restorations were successfully performed on each implant after a mean period of 6 months and no further complications occurred. In 11 out of 14 implants, an improvement of the papilla index was observed from baseline to 1 year follow-up whereas 3 implants showed a decrease of this index. Conclusion: The results from this prospective case series suggest that immediately restored implants using a final pre-shaped zirconium abutment in esthetic zone display favorable implant and prosthodontic outcomes and seems to allow an adequate papilla index improvement in most of the cases. http://hdl.handle.net/2268/145375 Title: Early Implant placement in socket preservations: 12-month results of a prospective case series. <br/> <br/>Author, co-author: DETHIER, Frédéric; LECLOUX, Geoffrey; ROMPEN, Eric; LAMBERT, France <br/> <br/>Abstract: Objectives: The aim of this study was to evaluate the clinical and histological outcomes of implant placed after socket preservation procedures in the esthetic zone. Implant survival rate and biological complications were recorded during a follow-up period of 1 year. Materials and methods: A series of 12 patients needing the replacement of a single tooth in the esthetic zone were included in the present study. The hopeless teeth were extracted atraumatically, the sockets were filled with bovine hydroxyapatite (0.25-1mm particles) and the sites were covered with a saddled connective tissue graft. After a healing period of 3 months, biopsies were retrieved in the socket preservation sites and implants were placed. The patients were followed for a period of 1 year. Results: The etiologies of tooth loss were : endodontic (9), caries (1), periodontal (1), and traumatic (1). A total of 12 implants (10 incisors, 2 premolars) were placed on 12 patients (6 men / 6 women) aged from 24 to 61 (42,3 – 11,91). All implant reached an adequate primary stability (> 20N/cm2). 7 out of 12 implants were immediately restored with a temporary crown, and the définitive restorations were successfully placed in all cases. After a follow-up period of 1 year, all implants fulfilled strict success criteria for dental implants with regard to osteointegration, including the absence of peri-implant radiolucency, implant mobility, suppuration, and pain and no further complications occurred. Out of 12 sites only 7 biopsies were retrieved for histological analyses. New bone was found in the apical third of the socket in every specimen, in the mid-third in only 3 specimen and no bone was found in any of the spécimen in the more cervical third of the socket. Conclusion: The results from this prospective case series suggest that early implant placement in extraction socket site seems to display good clinical outcomes despite the incomplete bone regeneration in the socket at 3 months. http://hdl.handle.net/2268/145374 Title: Dental extractions in patients treated with intravenous bisphosphonates and risk of osteonecrosis of jaws. <br/> <br/>Author, co-author: GAUDIN, Elise; HERION, Francine; ROMPEN, Eric; LAMBERT, France <br/> <br/>Abstract: Aim : Dental extraction remains contra-indicated in patients treated with intravenous (IV) bisphosphonates for oncology reasons because of the high risk of bisphosphonate-related osteonecrosis of the jaw (BRONJ). The objective of the present abstract was to present a preventive tooth extraction protocol in patients treated with IV bisphosphonates based on the surgical removal of the alveolar process. The second objective was to identify potential risk factors to develop BRONJ. Material and Methods : 17 patients treated with IV bisphosphonate and needing at least a tooth extraction, were included. A standardized extraction protocol was followed, including alveolectomy of at least 50% of the alveolar process, pre and post-operative antibiotherapy was administrated. The patients were followed for a mean period of 29 months (min:3 -max:62). Results : In all, 17 patients and 22 extraction sites mandible (15), maxilla (7) were involved in the study. No signs of inflamed tissue or necrotic exposed bone in any patient were observed during the follow-up period and the level of comfort for the patient was improved in all cases. Nevertheless, when a careful screening of the healing area was made using a probe, in 4 out of 22 (18,2%) sites, a remaining bone contact was found and appeared to be related location (mandible), duration of biphosphonate treatment and to concomitant. Conclusion : The present cases series suggests that the described extraction protocol in IV biphosphonate patients allowed 100% bone healing and complete soft tissues healing in 81.8% of the extraction sites.The sites that have not fully recovered seemed to be related to different factors. http://hdl.handle.net/2268/145371 Title: Marginal bone resorption and marginal bone level around implants in the posterior mandible: A 4-year retrospective study. <br/> <br/>Author, co-author: LAMBERT, France; Geron, Caroline; LECLOUX, Geoffrey; ROMPEN, Eric <br/> <br/>Abstract: Long-term bone remodelling of implant placed in the posterior mandibule: a radiological study. France Lambert, Kim Vincent, Caroline Geron, Geoffrey Lecloux, Eric Rompen. Purpose: The aim of this study was to analyse direct and long-term (4 years) marginal bone remodelling of various implant systems placed in the posterior mandibule with a single stage approach. Materials and methods: 50 partially edentulous patients received a total of 114 implants in the posterior mandibule (TE implant, Straumann®, Switzerland; Replace® Select Straight, Nobel Biocare, Sweden; Branemark System® MKIV, Nobel Biocare, Sweden). All implants were non-submerged, and loaded 8 to 12 weeks post surgery. X-rays were taken at baseline, 6 weeks, after loading and at long-term. Using a image processing program (Image J), bone losses were measured at each time point. Bone levels were also recorded using the first thread as reference point. Results: The mean bone loss reached 0.506±0.498 mm at 6 weeks, 0.798±0.599 after loading and 1.037±0.799 after 4 years. Bone losses were significatively higher on smokers and on patients displaying signs of bruxism. No statistical difference was found between the different implant types. Conclusion: 50% of the bone loss had already occurred within the 6 weeks post surgery with all implant types. Higher bone losses were often associated to risk factors such as tabacco addiction and bruxism. http://hdl.handle.net/2268/145370 Title: Patient morbidity after 2 different surgical protocols to treat miller class I recession in the anterior maxilla: A Comparaitive Ramdomized Control Trial. <br/> <br/>Author, co-author: SALHI, Leila; ROMPEN, Eric; LECLOUX, Geoffrey; Seidel, Laurence; LAMBERT, France http://hdl.handle.net/2268/145369 Title: 3-D guided bone regeneration using autogenous bone block as space maintainer for bone augmentation in the anterior maxilla. <br/> <br/>Author, co-author: ARNAUD, Louis; LAMBERT, France; LECLOUX, Geoffrey; ROMPEN, Eric http://hdl.handle.net/2268/145368 Title: Sinus elevation and simultaneous implant placement: the influence of the remaining bone height. <br/> <br/>Author, co-author: Ronco, Vincent; LAMBERT, France; LECLOUX, Geoffrey; ROMPEN, Eric http://hdl.handle.net/2268/145367 Title: A minimally invasive approach for horizontal bone regeneration of the anterior maxilla. <br/> <br/>Author, co-author: ARNAUD, Louis; LAMBERT, France; Rompen, Eric http://hdl.handle.net/2268/145366 Title: Influence of collar design on palatal implant primary stability <br/> <br/>Author, co-author: Bolland, Fabrice; Ronco, Vincent; LAMBERT, France; Rompen, Eric http://hdl.handle.net/2268/145365 Title: Fixed implant rehabilitation of the edentulous maxilla: a systematic literature review. <br/> <br/>Author, co-author: LAMBERT, France; Weber, HP; Gallucci, German; Susarla, S. http://hdl.handle.net/2268/145364 Title: The best solution for you patient. A Biological Approach for Aesthetic Implant Dentistry. <br/> <br/>Author, co-author: LAMBERT, France; LECLOUX, Geoffrey; ROMPEN, Eric http://hdl.handle.net/2268/145363 Title: Influence of Biomaterials in Alveolar Bone Regeneration and Preservation <br/> <br/>Author, co-author: LAMBERT, France <br/> <br/>Abstract: Dental implants are nowadays a reliable solution to replace missing teeth and have been widely documented. However, they require a minimal bone quantity (in height and thickness). But alveolar bone defects are very frequent, for instance due to periodontitis, traumatism or acute dental infection. Moreover, a simple tooth extraction leads to significant bone resorption. Therefore, alveolar bone regeneration is often necessary in order to place implants and to restore the patient's dentition with implant-supported prosthesis. Even though alveolar bone reconstructions have been considered as traumatic, especially due to the need of a second surgical site for bone harvesting, techniques have evolved with the introduction of biomaterials. However, it is difficult to compare the influences of such biomaterials on osteogenesis and to elaborate on the advantages of one product over another. The overall objective of this thesis is to contribute to the understanding of the biological concept of alveolar bone regeneration, in particular sinus lift and socket preservation procedures. The influence of biomaterials on bone regeneration has been emphasized through preclinical and clinical studies. The number of commercially available biomaterials for bone regeneration is growing every day and some materials are not supported by strong scientific data in the literature. The first part of this thesis (Chapter 1) is dedicated to the characterization of several biomaterials often used in dentistry. The impact of their various characteristics on osteogenesis has been reviewed, from chemical aspect to micro- and macromorphology. Furthermore, a data sheet integrating the physico-chemical and morphological properties of each studied biomaterial has been developed as a tool for clinicians. Sinus floor elevation has often been considered as a bone graft. In 1996, a consensus conference on “sinus lift” took place and the procedure was qualified as “sinus bone-graft”. But new scientific evidence has shown that this qualification is not justified. Chapter 2 aims at understanding the physiology and the biological model of sub-sinusal bone augmentation by using either a simple blood clot, autogenous bone chips or biomaterials (BHA) as space fillers under the lifted sinusal membrane. If bone formation did occur with the 3 types of space fillers, the augmented volumes significantly dropped with the blood clot or the autogenous bone chips but remained stable with BHA. Therefore, a slowly resorbable biomaterial such as BHA might be suitable in sub-sinusal bone augmentation to prevent the re-expansion process. Understanding the biological concept of sinus lift procedures, several authors demonstrated the clinical efficacy of biomaterials when used alone in this specific model. Nevertheless, biomaterials known to be resorbable led to a lamellar bone architecture that might not be able to maintain the volume of the regenerated tissue over time. Moreover, many types of biomaterials are available and scientific evidence of short and long-term performance of newly introduced biomaterials is still poor. Chapter 3 aims at comparing the performances, in terms of bone formation, resorption rate and 3-D stability, of four calcium phosphate-based biomaterials often used for sub-sinusal bone augmentation, in a rabbit model. Particulated space-filling biomaterials seemed to be more efficient to promote osteogenesis compared to paste-like biomaterials. Highly resorbable biomaterials appeared to withstand intrasinusal pressure after a period of six months in rabbits. Non- or slowly resorbable biomaterials are of great interest in the dental field because the long-term stability of 3-D bone augmentation is a key factor for dental implant and aesthetic outcomes. Therefore, the mechanical and non-resorbable properties of titanium, known to be highly compatible in vivo and highly resistant to body fluid corrosion, are potential advantages for bone augmentation prior to dental implantation. Nevertheless, the use of titanium particles as space fillers in bone regeneration was weakly reported in the literature from a histological point of view. Thus, Chapter 4 compares the behavior and the effect of porous titanium particles versus the well-documented BHA. Even though both biomaterials allowed osteogenesis and adequate 3-D stability, the bone architecture, and more specifically the amount of bone-to-material contact (BMC), was significantly different. Inclusion of the particles in a carrier or in binding agents such as a collagen gel or fibers might be of interest in order to ease surgical handling. However, the possible influence of those collagen carriers on bone tissue responses remains poorly investigated. The objective of Chapter 5 was to investigate the effect of collagen at different stages of the osteogenesis process, still in the same rabbit model. The findings clearly showed the presence of inflammatory cells at an early stage of bone regeneration when collagenated xenogenic biomaterials were used compared to collagen-free xenogenic granules. Nevertheless, despite the transient inflammation, the final quantity of newly formed bone was similar in the various groups. The last two chapters of this thesis take some of the preclinical findings of the previous chapters to the clinical field. The objective of Chapter 6 was to assess the clinical outcome of a minimalized sub-sinusal bone augmentation procedure using only biomaterials, simultaneously with the placement of 102 non-submerged implants in 40 patients. Implant and prosthodontic survival rates as well as complications were evaluated after a follow-up period of 2 to 6 years. This clinical trial emphasized that, if the amount of remaining bone height is sufficient to ensure implant primary stability, their placement can be performed simultaneously with sinus lifting, even in a non-submerged fashion. This procedure reduces the number of surgeries and the time before prosthetic rehabilitation. The objective of Chapter 7 was to to develop a new method to objectively evaluate in humans the 3-D volume variation of alveolar socket preservation over time by means of computed tomography and 3-D image analysis. Short summary: Before placing dental implants, alveolar bone regeneration is often required due to bone defects caused by periodontitis, traumatism or even a simple tooth extraction. Bone augmentation surgical procedures have very much evolved thanks to a better understanding of biological processes and to the introduction of biomaterials. The overall objective of this thesis is to bring a contribution to the understanding of the biological concept of alveolar bone regeneration, and in particular sinus lift and socket preservation procedures. The influence of biomaterials on bone regeneration has been emphasized through preclinical and clinical studies. http://hdl.handle.net/2268/145362 Title: Influence of space-filling materials in sub-sinusal bone augmentations : BHA vs BCP vs Beta-TCP vs Nano HA. <br/> <br/>Author, co-author: LAMBERT, France