http://hdl.handle.net/2268/93 Search this channel search http://orbi.ulg.ac.be/simple-search http://hdl.handle.net/2268/110806 Title: The cognitive modulation of pain: hypnosis- and placebo-induced analgesia. <br/> <br/>Author, co-author: Kupers, Ron; Faymonville, Marie-Elisabeth; Laureys, Steven <br/> <br/>Abstract: Nowadays, there is compelling evidence that there is a poor relationship between the incoming sensory input and the resulting pain sensation. Signals coming from the peripheral nervous system undergo a complex modulation by cognitive, affective, and motivational processes when they enter the central nervous system. Placebo- and hypnosis-induced analgesia form two extreme examples of how cognitive processes may influence the pain sensation. With the advent of modern brain imaging techniques, researchers have started to disentangle the brain mechanisms involved in these forms of cognitive modulation of pain. These studies have shown that the prefrontal and anterior cingulate cortices form important structures in a descending pathway that modulates incoming sensory input, likely via activation of the endogenous pain modulatory structures in the midbrain periaqueductal gray. Although little is known about the receptor systems involved in hypnosis-induced analgesia, studies of the placebo response suggest that the opiodergic and dopaminergic systems play an important role in the mediation of the placebo response. http://hdl.handle.net/2268/26764 Title: Hypnosis as adjunct therapy in conscious sedation for plastic surgery <br/> <br/>Author, co-author: Faymonville, Marie; Fissette, Jean; Mambourg, P.-H.; Roediger, Laurence; Joris, Jean; Lamy, Maurice http://hdl.handle.net/2268/26643 Title: Hypnosis with conscious sedation instead of general anaesthesia? Applications in cervical endocrine surgery. <br/> <br/>Author, co-author: Meurisse, Michel; Defechereux, Thierry; Hamoir, Etienne; Maweja, Sylvie; Marchettini, P.; Gollogly, L.; Degauque, C.; Joris, Jean; Faymonville, Marie <br/> <br/>Abstract: Between April 1994 and June 1997, 197 thyroidectomies and 21 cervical explorations for hyperparathyroidism were performed under hypnosedation (HYP) and compared to the operative data and postoperative courses of a closely-matched population (n = 121) of patients operated on under general anaesthesia (GA). Conversion from hypnosis to GA was needed in two cases (1%). All surgeons reported better operating conditions for cervicotomy using HYP. All patients having HYP reported a very pleasant experience and had significantly less postoperative pain while analgesic use was significantly reduced in this group. Hospital stay was also significantly shorter, providing a substantial reduction of the medical care costs. The postoperative convalescence was significantly improved after HYP and full return to social or professional activity was significantly shortened. We conclude that HYP is a very efficient technique providing physiological, psychological and economic benefits to the patient. http://hdl.handle.net/2268/26639 Title: Hypnoanesthesia for endocrine cervical surgery: a statement of practice. <br/> <br/>Author, co-author: Defechereux, Thierry; Meurisse, Michel; Hamoir, Etienne; Gollogly, L.; Joris, Jean; Faymonville, Marie <br/> <br/>Abstract: OBJECTIVES: To assess the feasibility of endocrine cervical surgery under hypnoanesthesia as a valuable, safe, efficient, and economic alternative to general anesthesia. METHODS: Between April 1994 and June 1997, 197 thyroidectomies and 21 cervical explorations for hyperparathyroidism were performed under hypnoanesthesia (HYP) using Erikson's method. Operative data and postoperative course of this initial series were compared to a contemporary population of patients (n = 119) clinically similar except that they declined HYP or were judged unsuitable for it, and who were therefore operated on under general anesthesia (GA). RESULTS: The surgeons all reported better operating conditions for cervicotomy using HYP. Conversion from hypnosis to GA was needed in two cases (1%). All patients having HYP reported a pleasant experience and, keeping in mind that the GA group is not a randomly assigned control group, both had significantly less postoperative pain and analgesic use. Hospital stay was also significantly shorter, providing a substantial reduction in the costs of medical care. The postoperative convalescence was significantly improved after HYP and a full return to social or professional activity was significantly quicker. CONCLUSION: From this study, we conclude that HYP is an effective technique for providing relief of intraoperative and postoperative pain in endocrine cervical surgery. The technique results in high patient satisfaction and better surgical convalescence. This technique can therefore be used in most well-chosen patients and reduces the socioeconomic impact of hospitalization. http://hdl.handle.net/2268/26627 Title: Hypnosédation: une nouvelle technique anesthésique <br/> <br/>Author, co-author: Kirsch, Murielle; Joris, Jean; Faymonville, Marie http://hdl.handle.net/2268/23720 Title: Development of thymus autografts under the kidney capsule in the pig: a new 'organ' for xenotransplantation <br/> <br/>Author, co-author: Lambrigts, Denis; Franssen, Colette; Martens, Henri; Van Calster, Pierre; Meurisse, Michel; Geenen, Vincent; Renard, Chantal; Dewaele, A.; Coignoul, Freddy; Lamy, Maurice; Alexandre, Guy P.J. http://hdl.handle.net/2268/9618 Title: Hypnose, hypnosédation. Conceptions actuelles et leurs applications en chirurgie plastique <br/> <br/>Author, co-author: Faymonville, Marie-Elisabeth; Fissette, Jean; Mambourg, P. H.; Delchambre, A.; Lamy, Maurice http://hdl.handle.net/2268/9579 Title: Neural mechanisms of antinociceptive effects of hypnosis. <br/> <br/>Author, co-author: Faymonville, Marie; Laureys, Steven; Degueldre, Christian; DelFiore, Guy; Luxen, André; Franck, Georges; Lamy, Maurice; Maquet, Pierre <br/> <br/>Abstract: BACKGROUND: The neural mechanisms underlying the modulation of pain perception by hypnosis remain obscure. In this study, we used positron emission tomography in 11 healthy volunteers to identify the brain areas in which hypnosis modulates cerebral responses to a noxious stimulus. METHODS: The protocol used a factorial design with two factors: state (hypnotic state, resting state, mental imagery) and stimulation (warm non-noxious vs. hot noxious stimuli applied to right thenar eminence). Two cerebral blood flow scans were obtained with the 15O-water technique during each condition. After each scan, the subject was asked to rate pain sensation and unpleasantness. Statistical parametric mapping was used to determine the main effects of noxious stimulation and hypnotic state as well as state-by-stimulation interactions (i.e., brain areas that would be more or less activated in hypnosis than in control conditions, under noxious stimulation). RESULTS: Hypnosis decreased both pain sensation and the unpleasantness of noxious stimuli. Noxious stimulation caused an increase in regional cerebral blood flow in the thalamic nuclei and anterior cingulate and insular cortices. The hypnotic state induced a significant activation of a right-sided extrastriate area and the anterior cingulate cortex. The interaction analysis showed that the activity in the anterior (mid-)cingulate cortex was related to pain perception and unpleasantness differently in the hypnotic state than in control situations. CONCLUSIONS: Both intensity and unpleasantness of the noxious stimuli are reduced during the hypnotic state. In addition, hypnotic modulation of pain is mediated by the anterior cingulate cortex. http://hdl.handle.net/2268/9578 Title: Comment utiliser l'hypnose en anesthésie <br/> <br/>Author, co-author: Faymonville, Marie; Joris, Jean; Lamy, Maurice http://hdl.handle.net/2268/9577 Title: Neural mechanisms of antinociceptive effects of hypnosis <br/> <br/>Author, co-author: Faymonville, Marie-Elisabeth; Laureys, Steven; Degueldre, Christian; Delfiore, Guy; Luxen, André; Franck, Georges; Lamy, Maurice; Maquet, Pierre <br/> <br/>Abstract: BACKGROUND: The neural mechanisms underlying the modulation of pain perception by hypnosis remain obscure. In this study, we used positron emission tomography in 11 healthy volunteers to identify the brain areas in which hypnosis modulates cerebral responses to a noxious stimulus. METHODS: The protocol used a factorial design with two factors: state (hypnotic state, resting state, mental imagery) and stimulation (warm non-noxious vs. hot noxious stimuli applied to right thenar eminence). Two cerebral blood flow scans were obtained with the 15O-water technique during each condition. After each scan, the subject was asked to rate pain sensation and unpleasantness. Statistical parametric mapping was used to determine the main effects of noxious stimulation and hypnotic state as well as state-by-stimulation interactions (i.e., brain areas that would be more or less activated in hypnosis than in control conditions, under noxious stimulation). RESULTS: Hypnosis decreased both pain sensation and the unpleasantness of noxious stimuli. Noxious stimulation caused an increase in regional cerebral blood flow in the thalamic nuclei and anterior cingulate and insular cortices. The hypnotic state induced a significant activation of a right-sided extrastriate area and the anterior cingulate cortex. The interaction analysis showed that the activity in the anterior (mid-)cingulate cortex was related to pain perception and unpleasantness differently in the hypnotic state than in control situations. CONCLUSIONS: Both intensity and unpleasantness of the noxious stimuli are reduced during the hypnotic state. In addition, hypnotic modulation of pain is mediated by the anterior cingulate cortex. http://hdl.handle.net/2268/2394 Title: Hypnose et perception de la douleur <br/> <br/>Author, co-author: Vanhaudenhuyse, Audrey; Boveroux, Pierre; Boly, Mélanie; Schnakers, Caroline; Bruno, Marie-Aurélie; Kirsch, Murielle; Demertzi, Athina; Lamy, Maurice; Maquet, Pierre; Laureys, Steven; Faymonville, Marie-Elisabeth <br/> <br/>Abstract: Improvement in functional neuroimaging allows researchers to disentangle the brain mechanisms involved in the pain modulation encountered during hypnosis. It has been shown that the anterior cingulate and prefrontal cortices are important in the modulation of incoming sensory and noxious input. Moreover, clinical studies in certain types of surgery (eg thyroidectomy, mastectomy and plastic surgery) have demonstrated that hypnosis may avoid general anesthesia.