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See detailDistribution and composition of organic carbon in the Tana River Basin, (Kenya)
Tamooh, F.; van den Meersche, K.; Borges, Alberto ULg et al

Poster (2011)

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See detailEtude des interactions membranaires de dérivés de l’acide glucuronique par calorimétrie à titrage isotherme
Laurent, Pascal ULg; Razafindralambo, Hary ULg; Paquot, Michel ULg

Poster (2011)

Dans le cadre de la valorisation de la biomasse et des glucides provenant de l’hydrolyse de matières premières renouvelables, différents dérivés d’acides uroniques ont été synthétisés en vue d’évaluer ... [more ▼]

Dans le cadre de la valorisation de la biomasse et des glucides provenant de l’hydrolyse de matières premières renouvelables, différents dérivés d’acides uroniques ont été synthétisés en vue d’évaluer leurs propriétés en tant qu’agents tensioactifs biocompatibles et biodégradables. Une nouvelle stratégie de synthèse assistée par micro-ondes, efficace et respectueuse de l'environnement, a par ailleurs permis de synthétiser quantitativement différentes D-glucofuranosidurono-6,3-lactones monosubstituées hydrosolubles au départ d'acide D-glucuronique non protégé en utilisant un catalyseur acide supporté. Ces lactones appartiennent à la famille des glycosurfactants non-ioniques dont les applications couvrent un vaste domaine, aussi bien dans l’industrie pharmaceutique, cosmétique ou alimentaire. Une première approche en vue d’évaluer leurs activités biologiques consiste en l’étude des paramètres d’interactions moléculaires de ces lactones vis-à-vis d’une membrane biologique modèle (1-palmitoyl-2-oleyl-sn-glycerol-3-phosphatidylcholine) par calorimétrie à titrage isotherme (Isothermal Titration Calorimetry – ITC). [less ▲]

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See detailSedimentology and magnetic susceptibility on a continuous Lower Givetian to Lower Famennian fore-reef succession (Sauerland, Germany) : A new example which reinforce the use of MS for long-distance correlations (Germany, Belgium and Moravia).
Pas, Damien ULg; Da Silva, Anne-Christine ULg; Boulvain, Frédéric ULg et al

Poster (2011)

This study focuses on the continuous Givetian-Frasnian section of the abandoned Burgberg quarry (Messinghausen Anticline, northern margin of the Rhenish Mountains). The exposed section (102 m thick ... [more ▼]

This study focuses on the continuous Givetian-Frasnian section of the abandoned Burgberg quarry (Messinghausen Anticline, northern margin of the Rhenish Mountains). The exposed section (102 m thick) covers a well constraint stratigraphic interval starting at the base of the Givetian (Stritzke 1991;Aboussalam et al., 2003) and according to Stritzke (1991) and our new datations ending within the Lower Famennian. The Middle-Upper Devonian shelf-edge within the Rheinisches Schiefergebirge can be traced from the supposed position along the southern rim of the Dinant Syncline and the Eifel Synclines, northwards along a line connecting the southern margin of the Devonian reefal outcrops of Attendorn and Brilon (Krebs 1967, 1974). The depositional setting of the investigated section corresponds to complex slope and basinal environments where reworked material from the proximal Brilon platform (located to the north) and basin deposits coexist. Thus, this section allows to follow the evolution of the Givetian-Frasnian Brilon platform (e.g., Machel 1990; Stritze 1990, 1991) in a deeper setting. Petrographic analysis of more than 330 thin-sections leads to the identification of 7 microfacies which are integrated into a palaeoenvironmental model. Microfacies curve evolution shows two main trends. A shallowing upward trend ending within a typical proximal slope setting (dismantling of the platform) followed by a deepening upward trend which is characterized by several meter of pelagic mudstone within the upper part of the studied section. Magnetic susceptibility variations in sedimentary rocks, have commonly been interpreted as related to variations of detritic inputs through climatic or sea level changes (Crick et al., 1994). The magnetic susceptibility (MS) study of more than 330 samples from this long-time fore-reef carbonated succession is an opportunity to better constraint our sedimentological interpretations. To do so, we propose a comparison between general MS trends and some parameters such as microfacies and relative sea level fluctuations interpreted on the basis of the sedimentological study. The relatively long stratigraphic interval covered by the Burgberg section offers a good opportunity to compare our data with the time equivalent Devonian sections of the Ardennes (Belgium) and Moravian karst area (Czech Republic) (Boulvain et al., 2010). And thus to test the magnetic susceptibility tool for long-distance correlation between stratigraphically well constraint sections. [less ▲]

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See detailDisulfide bond assignment and folding characterization of peptide toxins by Ion Mobility Mass Spectrometry
Echterbille, Julien ULg; Quinton, Loïc ULg; Rosu, Frédéric ULg et al

Poster (2011)

Introduction Animal venoms are mainly composed of peptide toxins, which are highly structured by several disulfide bridges. Disulfide bridges are a key feature as (i) they increase the toxins efficiency ... [more ▼]

Introduction Animal venoms are mainly composed of peptide toxins, which are highly structured by several disulfide bridges. Disulfide bridges are a key feature as (i) they increase the toxins efficiency by lowering their immunogenicity; (ii) they provide the adequate conformation for high affinity binding to the biological receptor. The sequencing and the determination of the cysteine pairing is still challenging and therefore an important step in their structure analysis and the understanding of their interactions with receptors. In this work, we present a new strategy to sequence structured toxins and assign S-S bridges using ion mobility resolved MS/MS. Methods The method relies on the analysis of partially reduced multiple-disulfide peptide. The mixture of the different forms is resolved by ion mobility, followed by MS/MS acquisition on each mobility separated species. The proof of concept has been successfully conducted on α-CnI, a toxin purified from the venom of Conus consors marine snail. The toxin sequence is GRCCHPACGKYYSC-NH2. It contains four cysteines linked together with two disulfide bridges. α-CnI was partially reduced by a small excess of tris(carboxyethyl)phosphine (10:1) at 56°C during 30min. The resulting mixture was purified by ZipTip C18 micro columns before analysis by infusion nanoESI-Synapt-G2. Fragmentation was performed after the mobility cell, to obtain specific fragments of each species. Mobilograms and mass spectra were analyzed using MassLynx (v4.1) and Driftscope (v2.1) from Waters. Preliminary data Partial reduction of a-CnI was performed in order to obtain a mixture of oxidized (the two disulfides are formed), reduced (the two disulfides have been reduced) and partially reduced forms (only one of the two disulfides has been reduced). The arrival time distribution of triply charged ions reveals the presence of 4 different species, characterized by a different relative cross sections in the gas-phase. The charge state of the ions influences the ion mobility separation. Mass matching allows identifying the species: the first mobility (the most compact structure) was identified to be the oxidized folded toxin (M=1541.58 Da). The latest peak, corresponding to the larger cross-section, was identified as the fully reduced toxin (M=1545.6 Da). The second and the third mobility peaks were attributed to the two partially reduced forms in which only one disulfide bridge was reduced (M=1543.59 Da). The change in ion mobility depends on which S-S bridge is reduced. Ion mobility separated species give characteristic fragment ions upon fragmentation in the transfer cell (i.e. after ion mobility separator). Interestingly, fragment ions coming from partially reduced species, especially the C-S or S-S bond cleavages, clearly indicates that the disulfide linkage of α-CnI is (Cys1-Cys3) and (Cys2-Cys4) as expected from literature. The method is now being applied with success to more complex systems containing 3 or 4 disulfide bridges. The influence of the charge state on the mobility separation is systematically analyzed in terms of structural implications. Novel aspect Sequencing and disulfide bridges assignment of peptide toxins using ion mobility resolved MS/MS [less ▲]

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See detailTransient reduction of placental angiogenesis in PAI-1 deficient mice
LABIED, Soraya ULg; Blacher, Silvia ULg; Carmeliet, P et al

Poster (2011)

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See detailEvolutionary significance and trade-offs in life-history traits associated to ecological specialization and mating systems in the liverwort genus Radula Dumort.
Laenen, Benjamin ULg; Devos, Nicolas; Renner, Matt et al

Poster (2011)

Shifts in mating systems are amongst the most common and important transitions in plants and are correlated with a suite of life-history traits. The evolution of mating systems and their relationships to ... [more ▼]

Shifts in mating systems are amongst the most common and important transitions in plants and are correlated with a suite of life-history traits. The evolution of mating systems and their relationships to gametophyte size, sexual reproduction, formation of asexual diaspores, and ecological specialization, is examined here in the leafy liverwort genus Radula.More specifically, we attempt to answer the following questions:(1)What is the ancestral mating system in Radula? (2)Are shifts from one mating system to another directional or random? (3)How does the evolution of mating systems correlate with the evolution of other related life history traits and, in particular, the specialization to temporary habitats? (4)What are the contingence relationships and order of acquisitionof those traits? [less ▲]

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See detailSeed dispersal by western lowland gorillas (G. g. gorilla) in south east Cameroon
Petre, Charles-Albert ULg; Tagg, Nikki; Beudels-Jamar, Roseline et al

Poster (2011)

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See detailUnpredictable photocatalytic ability of H2-reduced rutile-TiO2 xerogel in the degradation of dye-pollutants under UV and visible light irradiation
Páez Martínez, Carlos ULg; Lambert, Stéphanie ULg; Poelman, Dirk et al

Poster (2011)

Photocatalytic degradation of organic and inorganic pollutants on the TiO2 semiconductor has been extensively studied as a way to solve environmental problems relating to wastewater and polluted air ... [more ▼]

Photocatalytic degradation of organic and inorganic pollutants on the TiO2 semiconductor has been extensively studied as a way to solve environmental problems relating to wastewater and polluted air. Anatase and rutile are the most commonly used crystalline structures of TiO2, with anatase showing a higher photocatalytic activity attributed to its higher specific surface area and its favourable band gap energy (Eg). However, its high band gap (Eg = 3.2 eV) implies the use of UV light (lambda ≤ 380 nm) to inject electrons into the conduction band (TiO2(e-CB)) and to leave holes in the valence band (TiO2(h+VB)). Although the low band gap energy of rutile-TiO2 (Eg = 3.02 eV) allows rutile to potentially absorb more solar energy than anatase, the anatase-to-rutile phase transition leads to the collapse of the TiO2 specific surface area, which may result in a decrease in the photocatalytic activity of rutile. Low specific surface area and therefore poor absorption properties lead to strong limitations in exploring the photo-efficiency of rutile. Nevertheless, rutile has been proved to be comparable to anatase in its photoelectrochemical properties when used in dye-sensitized solar cells. In the present study, a new process for the reduction of rutile-TiO2 xerogel under hydrogen flow was developed to enhance the photocatalytic activity of TiO2 materials synthesized by the sol-gel process. So a series of H2-reduced TiO2 xerogels of low specific surface area was prepared by hydrolysis and condensation of tetraisopropoxy titanium(IV) in 2-methoxyethanol. The gels were dried under vacuum, calcined in air at different temperatures (400°C, 500°C and 700°C) and finally reduced in H2 at 400 °C. The materials were characterized by X-ray diffraction, transmission electron microscopy (TEM), FT-IR spectroscopy and UV/Visible diffuse reflectance spectroscopy. The texture was determined by nitrogen adsorption-desorption measurements. The effects of the calcination/reduction treatments on the adsorption of methylene blue (MB) in aqueous solution and on the photocatalytic degradation of MB and crystal violet (CV) under UV and visible light irradiation were also evaluated. Results showed predictable modifications in the physico-chemical properties caused by the annealing of TiO2 xerogel at high calcination temperature (700 °C), such as a total anatase-to-rutile phase transition and a considerable loss of specific surface area from 260 to 2 m2 g-1. However, the higher degree of reduction exhibited by the rutile-TiO2 lattice led to unpredictable photocatalytic activity for the dye conversion under UV and visible light irradiation: the loss of specific surface area of the rutile-TiO2 sample was compensated by the increase in the affinity of this sample for the dye. Under UV light irradiation, the rutile-TiO2 xerogel obtained after a calcination at 700 °C showed a similar level of photoactivity as the one obtained with anatase-TiO2 xerogels obtained by calcination at 400 °C and 500 °C. Under visible light, unlike anatase-TiO2 xerogels, the rutile-TiO2 xerogel showed a higher dye photoconversion rate per external surface area (40 times higher) than the commercial TiO2 Degussa P25. [less ▲]

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See detailImpacts de nos actions d’accompagnement d’enseignants en développement professionnel au sein du Master Complémentaire Formasup
Delfosse, Catherine ULg; Dupont, Chantal ULg; Jérôme, Françoise ULg et al

Poster (2011)

Présentations des modalités d'analyse du master complémentaire en pédagogie de l'enseignement supérieur pour le réguler.

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See detailAqueous and non-aqueous sol-gel preparation of TiO2 films for the photocatalytic oxidation of ethanol in air
Cimieri, Iolanda; Poelman, Hilde; Lambert, Stéphanie ULg et al

Poster (2011)

One of the most versatile methods to prepare TiO2 fine powders and films is the sol-gel technique. It offers many advantages, among which the possibility to control the stoichiometry, work in mild and ... [more ▼]

One of the most versatile methods to prepare TiO2 fine powders and films is the sol-gel technique. It offers many advantages, among which the possibility to control the stoichiometry, work in mild and ambient atmospheric conditions and achieve high purity and homogeneity of the final product. Stable TiO2 sols were synthesized by an aqueous sol-gel process using titanium tetraisopropoxide (TTIP) as precursor and nitric acid in water as hydrolyzing agent. The aim of the present study was to investigate the influence of different solvents and different amounts of HNO3 on the photocatalytic activity of TiO2 in the breakdown of ethanol (EtOH) as VOC molecule under UV and visible light. In particular, ethanol, isopropanol and butanol were used as solvents and two different molar ratios of HNO3 with respect to TTIP (0.25 and 0.5 respectively) were used. Their effect was investigated with regard to the photocatalytic properties of the films obtained by spin coating on sodium free glass [1] and heat treated at 450°C in air. The microstructure, optical and morphological properties of the films were investigated using SEM, UV-Vis spectroscopy and ellipsometry. The nature of the crystalline phases was ascertained by X-ray diffraction and the surface area of the powders was measured by N2 adsorption. The porous TiO2 films obtained show quite good photocatalytic activity for the degradation of EtOH compared to titania films prepared using P25 Degussa as shown in Fig. 1. Further the photocatalytic properties of the thin films obtained by aqueous sol-gel method were compared with the activity of films prepared using the same titanium precursor by a non-aqueous sol-gel process, in which the hydrolysis is initialized by esterification reaction between acetic acid and alcohol. (Fig.1. EtOH degradation for P25 (green), non aqueous sol (purple) and aqueous sols prepared using ethanol as solvent and HNO3 in molar ratios 0.25(blue) and 0.50(red)) [1] H. Tomaszewski, K. Eufinger, H. Poelman, D. Poelman, R. De Gryse, P.F.Smet, G.B. Marin, Int. J. Photoenergy 8, 1 (2007) [less ▲]

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See detailSafety and Performance of Stochastic Targeted (STAR) Glycemic Control of Insulin and Nutrition - First Pilot Results
Shaw, Geoffrey M.; Le Compte, Aaron; Evans, Alicia et al

Poster (2011)

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See detailCaractérisation des pigments préhistoriques par analyse PIXE
Lebon, Matthieu; Beck, Lucile; Lahlil, Sophia et al

Poster (2011)

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See detailAnatomie descriptive de la cavité péritonéale par la péritonéographie scanographique : implications diagnostiques pratiques
OUHADI; MATERNE, R; GHEKIERE, O et al

Poster (2011)

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See detailIdentification and characterization of novel galectin-9 splice variants in endothelial cells
Heusschen, Roy ULg; De Bree, Martijn; Griffioen, Arjan et al

Poster (2011)

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See detailAn overview of the aims and plans of an ISSI Team: Investigating the Dynamics of Planetary Magnetotails
Jackman, C.; Andre, N.; Arridge, C. et al

Poster (2011)

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See detailEndogenous zinc modulates di-synaptic GABAergic transmission in the dentate gyrus
Grauert, A; Engel, Dominique ULg; Ruiz, AJ

Poster (2011)

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See detailThe influence of aromatic solvents on CuPC blue pigments in oil paintings
Defeyt, Catherine ULg; Wijnberg, Louise; Verbeeck, Muriel ULg et al

Poster (2011)

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See detailMacroH2A regulates the commitment of adult and embryonic stem cells to differentation
Creppe, Catherine ULg; Cantariño, N; Janich, P et al

Poster (2011)

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See detailReconstruction of satellite-derived sea surface temperature of the South China Sea in 2003-2009
Huynh, Thi Hong Ngu ULg; Alvera Azcarate, Aïda ULg; Beckers, Jean-Marie ULg

Poster (2011)

The South China Sea (SCS) is a large marginal sea in the tropical region where the percentage of missing data of the daily Advanced Very High Resolution Radiometer (AVHRR) sea surface temperature (SST) is ... [more ▼]

The South China Sea (SCS) is a large marginal sea in the tropical region where the percentage of missing data of the daily Advanced Very High Resolution Radiometer (AVHRR) sea surface temperature (SST) is very high. Here we use a relatively new technique, DINEOF (Data INterpolating Empirical Orthogonal Functions), to reconstruct the SST of the SCS in 2003-2009. Furthermore, a comparison between the reconstructed data and daily Tropical rainfall Measuring Mission Microwave Imager (TMI) SST is implemented. [less ▲]

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See detailOPTIMIZATION OF A NEW TWO-PLATE SCREENING METHOD FOR THE DETECTION OF ANTIBIOTIC RESIDUES IN MEAT.
Pham Kim, Dang; Degand, Guy ULg; Danyi, Sophie et al

Poster (2011)

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See detailGait feature extraction in Parkinson's disease using low-cost accelerometers
Stamatakis, Julien; Cremers, Julien ULg; Maquet, Didier ULg et al

Poster (2011)

The clinical hallmarks of Parkinson’s disease (PD) are movement poverty and slowness (i.e. bradykinesia), muscle rigidity, limb tremor or gait disturbances. Parkinson’s gait include slowness, shuffling ... [more ▼]

The clinical hallmarks of Parkinson’s disease (PD) are movement poverty and slowness (i.e. bradykinesia), muscle rigidity, limb tremor or gait disturbances. Parkinson’s gait include slowness, shuffling, short steps, freezing of gait (FoG) and/or asymmetries in gait. There are currently no validated clinical instruments or device that allow a full characterization of gait disturbances in PD. As a step towards this goal, a four accelerometer-based system is proposed to increase the number of parameters that can be extracted to characterize parkinsonian gait disturbances such as FoG or gait asymmetries. After developing the hardware, an algorithm has been developed, that automatically epoched the signals on a stride-by-stride basis and quantified, among others, the gait velocity, the stride time,the stance and swing phases, the single and double support phases or the maximum acceleration at toe-off, as validated by visual inspection of video recordings during the task. The results obtained in a PD patient and an healthy volunteer are presented. The FoG detection will be improved using time-frequency analysis and the system is about to be validated with a state-of-the-art 3D movement analysis system. [less ▲]

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See detailFirst assessment of the biogeochemistry of the Congo River and tributaries
Darchambeau, François ULg; Bouillon, S.; Wabakanghanzi, J. N. et al

Poster (2011)

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See detailSub-wavelength quantum imaging using uncorrelated single photon sources
von Zanthier, J.; Thiel, C.; Bastin, Thierry ULg et al

Poster (2011)

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See detailComparative Planetary Magnetotails
Bagenal, F.; Jackman, C.; Slavin, J. et al

Poster (2011)

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See detailIs the PASAT enough to detect working memory problems in MS patients? A comparison with another working memory test
DELRUE, Gaël ULg; MOYANO, Nicolas; JIMENEZ et al

Poster (2011)

We show that the PASAT is not the best test to evaluate working memory in mulitple sclerosis patients.

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See detailSynthesis by sol-gel process of visible light sensitive-TiO2 for the degradation of pollutants and microorganisms
Tasseroul, Ludivine ULg; Lambert, Stéphanie ULg; Páez Martínez, Carlos ULg et al

Poster (2011)

Since the discovery of photocatalytic decomposition of water on TiO2 electrodes by Fujishima and Honda [1], heterogenous photocatalysis has been widely studied for environmental applications ... [more ▼]

Since the discovery of photocatalytic decomposition of water on TiO2 electrodes by Fujishima and Honda [1], heterogenous photocatalysis has been widely studied for environmental applications. Photocatalytic processes are new technologies for waste water treatment because new compounds (alkanes, pesticides, dyes, etc.) in effluents are not readily degraded by the conventional treatments [2]. Oxidative processes can completely destroy organic pollutants [3] or microorganisms (bacteria, viruses, fungi, etc.) [4,5]. At this moment, the commercial Degussa P25 is the mostly used photocatalyst. Nevertheless, it requires UV light to be activated, that is why scientists try to activate TiO2 under visible light. The aim of this study is to synthesize photocatalysts activated by visible light and to evaluate their activity for the degradation of pollutants and microorganisms. The sol-gel process allows the direct introduction of visible light sensitive species like porphyrins inside the TiO2 matrix during the synthesis [6]. Two tetracarboxyphenyl porphyrins are synthesized for the sensitization of TiO2 to visible light : the metal free tetracarboxyphenyl porphyrin and the nickel tetracarboxyphenyl porphyrin. These porphyrins are characterized by 1H NMR, FT-IR and UV/Vis spectroscopies. They are introduced during the sol-gel synthesis of TiO2 matrix. Diffuse reflectance and FT-IR spectroscopies are used to ensure that porphyrins are incorporated inside the matrix of TiO2. Indeed, characteristic porphyrins peaks appear on spectra. The cristallinity and specific surfaces of catalysts are also determined by XRD and nitrogen adsorption-desorption measurements respectively. The depolluting efficiency of photocatalysts is evaluated for the degradation in water of p-nitrophenol, which is listed as one of the 114 organic pollutants by the Environmental Protection Agency in the US. After 6 h under visible light, 40 % of p-nitrophenol are degraded with some catalysts. The activity is influenced by i) the presence of porphyrins : the photoactivity increases with the amount of porphyrins ; ii) the nature of porphyrins : nickel porphyrins are more active than free metal porphyrins ; and iii) the crystallinity of catalysts : amorphous catalysts are less active than crystallized samples. The photocatalysts with the highest degradation rating of dyes will be selected for the degradation in water of Escherichia coli and Lactobacillus acidophilus. [1] A. Fujishima, K. Honda, Nature 238, 37-38 (1972) [2] P. Gogate, A. Pandit, Advances in Environmental Research 8, 501-551 (2004). [3] D. Chen, A. Ray, Water Research 32, 3223-3234 (1998) [4] R. Watts, S. Kong, M. Orr, G. Miller, B. Henry, Water Research 29, 95-100 (1995). [5] J. Hong, M. Otaki, Journal of Bioscience and Bioengineering 101, 185-189 (2006). [6] C. Wang, J. Li, G. Mele, G.M. Yang, F.-X. Zhang, L. Palmisano, G. Vasapollo, Applied catalysis 78, 218-226 (2007). [less ▲]

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See detailPreliminary results of financial analysis on poultry supply chains in Hanoi suburb, North-Vietnam
Phan Dang, Thang; Vu Dinh, Ton; Dogot, Thomas ULg et al

Poster (2011)

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See detailPEB: thermal oriented architectural modeling for building energy efficiency regulations
Leclercq, Pierre ULg; Juchmes, Roland ULg; Delfosse, Vincent ULg et al

Poster (2011)

As part of the overhauling of the building energy efficiency regulations (following European directive 2002/91/CE), the Wallonia and Brussels-Capital Region commissioned the LUCID to develop an optional ... [more ▼]

As part of the overhauling of the building energy efficiency regulations (following European directive 2002/91/CE), the Wallonia and Brussels-Capital Region commissioned the LUCID to develop an optional 3D graphic encoding module to be integrated with the core energy efficiency computation engine developed by Altran Europe. Our contribution consisted mostly in analyzing the target users’ needs and representations (ergonomics, UI, interactions) and implementing a bespoke 3D CAD modeler dedicated to thermal models of buildings taking into account the various geometrical and relational constraints specific to thermal modeling. [less ▲]

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See detailEffect of prenatal undernutrition of the chicken embryo on growth and metabolism up to day 7
Willems, Els; Willemsen, Hilke; Li, Yue et al

Poster (2011)

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See detailRapid regulation by glutamate of aromatase activity
Charlier, Thierry ULg; Ball, Gregory; Balthazart, Jacques ULg

Poster (2011)

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See detailMesure de la lordose thoracique du porc : méthode centroïde versus méthode de Cobb
Van Cauwenberge, H; Georis, P; Busoni, Valeria ULg et al

Poster (2011)

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See detailULTRASONOGRAPHIC APPEARANCE OF THE CISTERNA CHYLI IN THE DOG
Etienne, Anne-Laure ULg; Cavrenne, Romain ULg; Garcia et al

Poster (2011)

Introduction/Aims The cisterna chyli (CC) is a dilated and bipartite portion of the lymphatic channels coursing intimately along the abdominal aorta in the retroperitoneal space.1 The appearance of the CC ... [more ▼]

Introduction/Aims The cisterna chyli (CC) is a dilated and bipartite portion of the lymphatic channels coursing intimately along the abdominal aorta in the retroperitoneal space.1 The appearance of the CC of the dog has been described on magnetic resonance imaging.2 The aim of this poster is to describe the ultrasonographic appearance of the CC in 2 dogs with chylous ascitis and in 2 healthy dogs. Methods Abdominal ultrasonography was realised with a 7.5MHz microconvex transducer. A right or left lateral dorsal approach was used. The aorta (together with the cranial mesenteric artery in normal dogs) was used as the main landmark to localize the CC. The dogs with chylous ascites were a 4 year old female american cocker spaniel, with immune-mediated hemolytic anemia and thrombocytopenia and a 1 year old, spayed female whippet with recurrent pancreatitis. The 2 healthy dogs were a 7 year old Beagle and a 9 year old Jack Russell. The abdominal ultrasonography was realised within 2 hours after the meal in the healthy dogs. Results The CC was seen as a hypoechoic structure, without detectable flow, dorsal and to the right of the aorta. The CC was easily visible in the 2 dogs with chyloabdomen while it was more difficult to localize in the healthy dogs. The CC was tubular on the longitudinal images. On transverse images, the CC is elliptic or semilunar and may partially surround the aorta. The maximal width of the CC measured on transverse images varied from 2-3mm in the 2 healthy dogs to 4-8mm in the 2 dogs with chyloabdomen. In 3 patients some efferent/afferent lymphatic vessels were seen as thin hypoechoic tubes converging on the CC. Shape and size of the CC in the same animal were seen varying during the same ultrasonography or between different exams. Discussion/Conclusion The CC is visible by ultrasonography in dogs. Its visibility depends on different conditions like disease of the lymphatic system3, quality and distance of the meal. [less ▲]

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See detailLymphangiogenesis and extracellular matrix remodeling
Erpicum, Charlotte ULg; Detry, Benoît ULg; Paupert, Jenny ULg et al

Poster (2011)

Lymphangiogenesis, the formation of new lymphatic vessels from preexisting ones, is an important biological process associated with diverse pathologies, such as metastatic dissemination and graft ... [more ▼]

Lymphangiogenesis, the formation of new lymphatic vessels from preexisting ones, is an important biological process associated with diverse pathologies, such as metastatic dissemination and graft rejection. Our laboratory has previously identified MMP2 as a key regulator of lymphangiogenesis in vitro and in vivo. However, the exact function of MMP2 in this process is yet unknown. The present work aims at elucidating the mechanisms of MMP2 action during lymphangiogenesis. MMP2 could either act as a growth factor activator or as a regulator of matrix remodeling. To address this question, we studied the effect of MMP2 on lymphangiogenesis in an novel in vitro model of sprouting cells from small aggregates (spheroids) seeded in a collagen gel. In this model, quantification of the lymphangiogenic response is performed through computerized methods allowing the measurement of the distance of migration, but also the evaluation of how the cell are migrating. We evaluated the impact of MMP2 blockage through the use of physiological (TIMP2) or chemical inhibitors or by downregulating its expression with specific siRNA. The importance of extracellular matrix composition is evaluated by embedding these spheroids into different matrices (matrigel versus collagen; pepsinized collagen versus native collagen; different collagen concentrations). Our results reveal a modification of cell migration through collagen gel after MMP2 inhibition. The utilization of DQ collagen and microscopy refractance confirmed the importance of MMP2 collagenoyitic activity for lymphangiogenesis. [less ▲]

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See detailThe glycine receptor is functionally expressed in migratory interneurons and influences early cortical development
Avila Macaya, Ariel Salvatore ULg; Nguyen, Laurent ULg

Poster (2011)

The strychnine-sensitive glycine receptor (GlyR) is a member of the ligand-gated ion channel superfamily. In the adult, the GlyR is known to mediate fast inhibitory neurotransmission in the spinal cord ... [more ▼]

The strychnine-sensitive glycine receptor (GlyR) is a member of the ligand-gated ion channel superfamily. In the adult, the GlyR is known to mediate fast inhibitory neurotransmission in the spinal cord and in the brainstem. The GlyR has also been described in the embryonic cortex after embryonic day 19 (E19) (Flint et al., 1998) where it could participate in developmental processes, but its presence at earlier stages has not been documented. Since other neurotransmitter systems, i.e. GABA and its receptors, are known to be potent signals that control corticogenesis (Nguyen et al., 2001; Ik-Tsen et al., 2007), we wondered if glycine and its GlyR could also fulfill such a function. In this study, we analyze GlyR expression and its physiological function in the early development of the cortex using in vitro cultures of embryonic day 13 slices, patch-clamp, two photon microscopy and immunocytochemistry. [less ▲]

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See detailMacroH2A regulates the commitment of adult and embryonic stem cells to differentation
Creppe, Catherine ULg; Cantariño, N; Janich, P et al

Poster (2011)

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See detailPhysico chemical characterization of biosurfactants micelles or Physico-aggregates produced by B. subtilis during their membrane separation
Coutte, F.; Jauregi, P.; Lecouturier, D. et al

Poster (2011)

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See detailThick and crack-free nanocrystalline mesoporous TiO2 films obtained by capillary coating from aqueous solutions
Krins, Natacha ULg; Faustini, Marco; Louis, Benjamin et al

Poster (2011)

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See detailNovel HDAC/DNMT Twin Inhibitors Interfere with Angiogenesis
Shiva Shankar, Thammadihalli Veerasangaiah ULg; Sulka, Béatrice ULg; Blacher, Silvia ULg et al

Poster (2011)

DNA methylation and histone deacetylation are two key epigenetic modifications that play central role in regulation of gene expression. Several studies have shown that histone deacetylases (HDAC) and DNA ... [more ▼]

DNA methylation and histone deacetylation are two key epigenetic modifications that play central role in regulation of gene expression. Several studies have shown that histone deacetylases (HDAC) and DNA methyltransferases (DNMT) inhibitors are potent anti-angiogenic compounds. Though combination of HDAC and DNMT inhibitors are now being examined in clinical trials of hematological malignancies, little work has been done to understand the effect of this combination on physiological and tumoral angiogenesis. We have designed and tested a family of twin drugs with intrinsic HDAC and DNMT inhibitory activities in relevant models of angiogenesis in vitro (Human Umbilical Vein Endothelial Cells – HUVEC and aortic ring) and in vivo (chick chorioallantoic membrane and Zebrafish). We have identified a lead compound having quantifiable anti-angiogenic effect without cytotoxicity affecting global histone acetylation and DNA methylation levels. In order to elucidate its anti-angiogenic mechanism, we characterized gene expression pattern simultaneously with the methylation profile of HUVEC cells treated with the lead compound and reference epigenetic modulators. This approach based on parallel microarray analyses permitted us to underscore a list of genes exclusively affected by the lead compound but not by other HDAC or DNMT inhibitors. These genes were then analyzed using the Ingenuity Pathway software revealing potential involvement of a subset of genes in angiogenesis. Our present aim is to validate the expression levels of a series of genes with respect to epigenetic mechanisms (histone modifications and DNA methylation). Finally, the biological relevance of the target genes will be explored by RNA silencing. Hence, we are using these novel epigenetic modulators as a tool to understand the regulatory mechanism of angiogenesis and to develop effective approaches to treat cancer. [less ▲]

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See detailEarthworms smell microorganisms in soil
Zirbes, Lara ULg; Verheggen, François ULg; Mescher, Mark et al

Poster (2011)

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See detailDynamic Magnetic Resonance Perfusion: Influence of the Cardiac Cycle on Left Ventricle and Myocardial Signal Intensity Measurements
BROUSSAUD, T; AOUCHRIA, A; MANCINI, ISABELLE et al

Poster (2011)

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See detailMyocardial Dynamic Contrast-enhanced MR: Artifacts and Physiopathological Pitfalls
NCHIMI LONGANG, Alain ULg; RASKINET, B; MORAR, A et al

Poster (2011)

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See detailProduction subjective de rêve en milieu carcéral : une hypothèse adaptative
Englebert, Jérôme ULg; Gauthier, Jean-Marie ULg; Jacquemart, Catherine

Poster (2011)

Une étude sur le rêve n’est pas sans poser plusieurs questions épistémologiques et méthodologiques majeures. La première d’entre elles tient à l’essence même du rêve qui est un objet d’étude particulier ... [more ▼]

Une étude sur le rêve n’est pas sans poser plusieurs questions épistémologiques et méthodologiques majeures. La première d’entre elles tient à l’essence même du rêve qui est un objet d’étude particulier, étant strictement subjectif et difficilement objectivable. Le rêve n’existe dans la vie consciente qu’au passé ; il a une conscience uniquement rétrospective. Il existe donc un décalage temporel entre l’activité onirique et le discours sur le rêve. Ce hiatus temporel condamne donc le rêve à nous échapper dans sa finitude et pousse le chercheur à capituler face à la connaissance ultime et globale du monde imaginaire de l’individu. L’étude que nous avons réalisée se veut d’inspiration phénoménologique. Nous avons administré un questionnaire (questionnaire élaboré sous la supervision d’un collège d’experts travaillant en milieu carcéral) à une population de 48 détenus (43 hommes et 5 femmes) et à une population contrôle (appariée pour l’âge et le niveau d’étude). Le questionnaire était scindé en deux parties pour les détenus (rapport aux rêves avant l’enfermement [Gd.0] / rapport aux rêves maintenant [Gd.1]) et celui pour la population contrôle ne comprenait qu’une partie (rapport aux rêves maintenant [Gc]). Enfin, nous avons isolé trois groupes au sein de la population carcérale : Cp : Courte peine effectuée (maximum 90 jours), MP : Moyenne peine effectuée (plus de 90 jours et maximum 2 ans), LP : Longue peine effectuée (plus de 2 ans). Les résultats, qu’il conviendra de discuter dans le détail, mettent en évidence que l’activité onirique serait un mécanisme que le détenu utilise pour s’adapter à l’univers carcéral (la fréquence subjective de rêve et l’intérêt porté à ses rêves sont significativement plus importants pour le Gd.1 que le Gd.0 et le Gc). Mais ce constat tend à diminuer en fonction de la durée de la peine (au-delà de 2 ans d’enfermement [LP]). Nous pouvons expliquer cette diminution significative par un effet d’habituation (le rêve aurait permis un retour à une homéostasie psychique suffisante) ou par une abrasion du mécanisme. En effet, le rêve ne procurerait aucune modification dans le réel puisque le quotidien de l’enfermement reste le même. Privée de boucle de rétroaction, la fonction adaptative du rêve s’essoufflerait. [less ▲]

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See detailAnalyses biophysiques des interactions peptide-monocouches à l’interface air-eau
Nasir, Mehmet Nail ULg; Benichou, Emmanuel; Brevet, Pierre-François et al

Poster (2011)

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See detailThe effect of insulin injection on the glucose metabolism of the chicken embryo
Franssens, Lies; Willems, Els; Willemsen, Hilke et al

Poster (2011)

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See detailThe Influence of aromatic solvents on CuPc blue pigments
Defeyt, Catherine ULg; Vandenabeele, Peter; Lycke, Sylvia et al

Poster (2011)

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See detailSynthesis and hydrolytic stability of novel 3-[18F]fluoroethoxybis(1-methylethyl)silyl]propanaminebased prosthetic groups
collet, Charlotte; Lamandé-Langle, Sandrine; Balentova, Eva et al

Poster (2011)

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See detailCT Peritoneography: Normal Anatomy of the Peritoneal Cavity and Implications for Diseases Assessment
OUHADI; MATERNE, R; GHEKIERE, O et al

Poster (2011)

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See detailVariability of insulin sensitivity for diabetics and non-diabetics during the first 3 days of ICU stay
Pretty, Christopher G.; Le Compte, Aaron; PREISER, Jean-Charles ULg et al

Poster (2011)

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See detailElaboration of tantalum oxide and carbon nanotubes composite coatings on titanium for biomaterial applications
Maho, Anthony ULg; Linden, Stéphanie; Arnould, Christelle et al

Poster (2011)

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See detailHuman brucellosis in North-East Ecuador: prevalence, typifying Brucella spp., and risk factors
Ron-Roman, J; Benitez-Ortiz, Washington; Ron-Garrido, L et al

Poster (2011)

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See detailMacropinocytosis of human papillomaviruses in natural killer cells via CD16 induces cytotoxic granule exocytosis and cytokine secretion
Renoux, V; Langers, I; Clémenceau, B et al

Poster (2011)

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See detailCaractérisation des composés volatils des huiles d’olive produites dans des coopératives de la région orientale du Maroc
Tanouti, K.; Serghini-Caid, H.; Sindic, Marianne ULg et al

Poster (2011)

L'objectif principal de cette étude est de faire progresser nos connaissances sur le profil volatil des huiles d’olive produite dans les régions du Maroc oriental. L’identification des composés volatils des ... [more ▼]

L'objectif principal de cette étude est de faire progresser nos connaissances sur le profil volatil des huiles d’olive produite dans les régions du Maroc oriental. L’identification des composés volatils des échantillons d’huiles d’olive provenant des coopératives de la région orientale du Maroc et la comparaison aux profils de volatils d’huiles européennes a été réalisée on utilisant la méthode de la microextraction en phase solide (SPME) couplée à la GC/MS. [less ▲]

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See detailThick and crack-free nanocrystalline mesoporous TiO2 films obtained by capillary coating from aqueous solutions
Krins, Natacha ULg; Faustini, Marco; Louis, Benjamin et al

Poster (2011)

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See detailRelease and innate immune detection of host cell DNA mediate the adjuvant activity of aluminum salts
Marichal, Thomas ULg; Ohata, K; Bedoret, D et al

Poster (2011)

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See detailDéontologie de l'information : journée d'étude
Vanesse, Marc ULg

Poster (2010, December 14)

Journée de réflexion sur la déontologie journalistique avec le bâtonnier de l'Ordre des avocats de Liège, le secrétaire général du Conseil de déontologie, un journaliste d'investigation et le secrétaire ... [more ▼]

Journée de réflexion sur la déontologie journalistique avec le bâtonnier de l'Ordre des avocats de Liège, le secrétaire général du Conseil de déontologie, un journaliste d'investigation et le secrétaire général adjoint de l'Association des journalistes. [less ▲]

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See detailChanges in functional interactions during anaesthesia-induced loss of consciousness
Schrouff, Jessica ULg; Perlbarg, Vincent; Boly, Mélanie ULg et al

Poster (2010, December 12)

Consciousness has been related to the amount of integrated information that the brain is able to generate. In this paper, we tested the hypothesis that the loss of consciousness caused by propofol ... [more ▼]

Consciousness has been related to the amount of integrated information that the brain is able to generate. In this paper, we tested the hypothesis that the loss of consciousness caused by propofol anesthesia is associated with a significant reduction in the capacity of the brain to integrate information. To assess the functional structure of the whole brain, functional integration and partial correlations were computed from fMRI data acquired from 18 healthy volunteers during resting wakefulness and propofol-induced deep sedation. Total integration was significantly reduced from wakefulness to deep sedation in the whole brain as well as within and between its constituent networks (or systems). Integration was systematically reduced within each system (i.e., brain or networks), as well as between networks. However, the ventral attentional network maintained interactions with most other networks during deep sedation. Partial correlations further suggested that functional connectivity was particularly affected between parietal areas and frontal or temporal regions during deep sedation. Our findings suggest that the breakdown in brain integration is the neural correlate of the loss of consciousness induced by propofol. They stress the important role played by parietal and frontal areas in the generation of consciousness. [less ▲]

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