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See detailAnalysis of the mouse doublecortin gene promoter in neurons
Piens, Marie; Muller, Marc ULg; Lion, Michelle ULg et al

Poster (2005)

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See detailDu cours au dispositif d'apprentissage... ou du rôle d'enseignant à celui de concepteur-tuteur d'activités d'apprentissage à distance. Communication présentée au colloque EIAH 2005, Environnements Informatiques pour l'Apprentissage Humain
Denis, Brigitte ULg; Vandeput, Etienne ULg

Poster (2005)

Nous décrivons une stratégie de mise en œuvre d’un dispositif d’EAD (Enseignement à Distance) nécessitant peu de moyens matériels et logiciels, gérable par un seul enseignant. L’environnement d ... [more ▼]

Nous décrivons une stratégie de mise en œuvre d’un dispositif d’EAD (Enseignement à Distance) nécessitant peu de moyens matériels et logiciels, gérable par un seul enseignant. L’environnement d'apprentissage est basé sur un dosage entre travaux individuels et travaux collaboratifs et sur un schéma d'organisation particulier des activités. Ce dernier et la stratégie mise en place sont adaptables à de nombreux thèmes de réflexion traitables dans le cadre d’une activité à distance. [less ▲]

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See detailOxidative stress which occurs during chorioamnionitis induces production of prostaglandins by uterus
Temma-Asano, Kumiko; Shimoya, Koichiro; Tskitishvili, Ekaterine ULg et al

Poster (2005)

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See detailAssociation between S100B protein levels in the amniotic fluid and preeclampsia
Shimoya, Koichiro; Komoto, Yoshiko; Temma-Asano, Kumiko et al

Poster (2005)

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See detailCourtship behaviour at low and high water temperatures in the Alpine newt
Denoël, Mathieu ULg; Mathieu, Maryève; Poncin, Pascal ULg

Poster (2005)

Environmental factors are known to have a major effect on behavioral patterns of organisms. Among these factors, temperature particularly affects ectotherms. However, although many studies focused on ... [more ▼]

Environmental factors are known to have a major effect on behavioral patterns of organisms. Among these factors, temperature particularly affects ectotherms. However, although many studies focused on acoustic communication, the effect of environmental temperature on visual courtship displays and sexual performance has been little explored. The aim of this work was to determine the effect of temperature on the sexual behaviour of the Alpine newt Triturus alpestris in controlled laboratory conditions. Temperature had a major effect on the two sexes: at low temperatures, the frequencies of several displays, including sperm deposition, is lowered. This variation is in fact caused by the female responsiveness, which is temperature-dependent. However, some other behaviours, such as the fanning movement of the male’s tail (i.e., the main courtship display) are directly dependent on temperature: at lower temperatures, the tail beats at a lower rate but for a longer time. The similar reproductive success at the two temperatures indicates that breeding in cold water is not necessarily costly. It allows males and females to mate early in the season. This is particularly adaptive because, in many habitats, the reproductive period is shortened by drying or freezing conditions which may impair survival of branchiate offspring. [less ▲]

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See detailInterleukin-6 mediates subchondral osteoblasts-induced cartilage degradation
Henrotin, Yves ULg; Kaut, Elisabeth; Deberg, Michelle ULg et al

Poster (2005)

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See detailExperimental and numerical study of fracture healing in a murine fracture model
Geris, Liesbet ULg; Gerisch, A.; Maes, C. et al

Poster (2005)

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See detailUSING TOTAL ERROR AS DECISION CRITERION IN METHOD TRANSFER
Rozet, Eric ULg; Mertens, B.; Dewe, W. et al

Poster (2005)

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See detailThe study of S100B protein in patients with pre-eclampsia and IUGR
Komoto, Yoshiko; Shimoya, Koichiro; Tskitishvili, Ekaterine ULg et al

Poster (2005)

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See detailTRIMETHYLAMINE IN PLASMA OF LAMBS FED WITH RAPESEED MEAL
Wathelet, Jean-Paul ULg; Mabon, N.; Paquay, R. et al

Poster (2005)

In order to study the effects of aromatic choline esters, thirty Texel, Suffolk or crossbred lambs allocated to three groups are fed ad libitum with pasture hay and diets containing 0 % (control) or 25 ... [more ▼]

In order to study the effects of aromatic choline esters, thirty Texel, Suffolk or crossbred lambs allocated to three groups are fed ad libitum with pasture hay and diets containing 0 % (control) or 25% of each rapeseed meal. A specific technique is developed for trimethylamine determination in plasma. [less ▲]

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See detailOptimality of feeding on land versus in water in juvenile Alpine newts (Triturus alpestris veluchiensis)
Denoël, Mathieu ULg

Poster (2005)

Most newts experience both terrestrial and aquatic environments during their adult life. A large number of studies explored the feeding habits in the aquatic habitat while very few focused on the ... [more ▼]

Most newts experience both terrestrial and aquatic environments during their adult life. A large number of studies explored the feeding habits in the aquatic habitat while very few focused on the terrestrial component and none compared the two systems within a single population. The aim of this study was to find out which foraging tactic is the most successful in terms of energy intake. To this end, I analysed the feeding habits of metamorphosed juveniles in the Alpine newt inhabiting a Greek alpine lake and its surrounding lands. The diet reflected the range of prey available in the two habitats, but invertebrates, which fell on the water surface, were also ingested by aquatic newts. These two lifestyles had different energy outcomes because the highest number of terrestrial invertebrates taken in the terrestrial habitat than in the aquatic one provided higher energy gains to terrestrial juveniles. However, different mortality rates between habitats (highest probability of freezing risk on high-elevated lands than in deep waters) and an expected lower energy intake on land when air temperature is low could explain the persistence of the aquatic foraging tactic in the population. [less ▲]

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See detailEarly pregnancy detection in sheep. Secondary communication
Karen, Aly; Beckers, Jean-François ULg; Sulon, Joseph ULg et al

Poster (2005)

A szerzők a juhok vemhességének korai megállapítására összehasonlították a progeszteron- (P4) és a vemhességi fehérje (PAG) RIA-tesztek megbízhatóságát. A PAG-teszttel a nem vemhes állatok nagyobb ... [more ▼]

A szerzők a juhok vemhességének korai megállapítására összehasonlították a progeszteron- (P4) és a vemhességi fehérje (PAG) RIA-tesztek megbízhatóságát. A PAG-teszttel a nem vemhes állatok nagyobb biztonsággal voltak felismerhetők. Nagyszámú állaton (n=949 és 764) végzett rectalis ultrahangvizsgálattal a vemhességet pontosabban tudták megállapítani, ha az állatokat 12 óráig koplaltatták és vizsgálat közben a hasfalat a tőgy előtt felemelték. Az ultrahangvizsgálat és a PAG-teszt eredményeinek összehasonlításával megállapították, hogy az utóbbi megbízhatóbb eredményt ad. [less ▲]

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See detailConsequences of fish introductions on paedomorphic newts (Triturus alpestris and T. helveticus)
Denoël, Mathieu ULg; Dzukic, Georg; Kalezic, Milos

Poster (2005)

Fish stocking is largely recognized as a major thread to amphibian populations. Although it acts at a local level, it is widespread at a world scale. Despite this good knowledge, the effect of fish on ... [more ▼]

Fish stocking is largely recognized as a major thread to amphibian populations. Although it acts at a local level, it is widespread at a world scale. Despite this good knowledge, the effect of fish on alternative phenotypes has only been described in a few local studies. Our aim was to report on the loss of intraspecific heterochrony as a loss to diversity in determining the consequences of fish introductions on paedomorphs (morphs retaining gills at the adult stage) of two European species of newts. We surveyed almost all the main known paedomorphic populations of the Alpine (Triturus alpestris) and palmate (T. helveticus) newts, which all but one initially occupied fishless ponds and lakes in France, Italy, Slovenia, Bosnia, Montenegro, and Greece. Exotic fish were found in almost half of the studied aquatic habitats. Introductions involved several ornamental and large predatory species of fish. At all sites, in which fish were introduced, paedomorphs disappeared and metamorphs declined. The largest known populations of newts, including some endemic subspecies, were concerned. If measures are not taken to stop fish stocking, protect paedomorphs as conservation units, and restore natural habitats, all the largest paedomorphic populations may disappear in the near future. [less ▲]

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See detailMicrowave-Enhanced Ruthenium Catalysed Atom Transfer Radical Additions
Richel, Aurore ULg; Leclerc, Alain; Demonceau, Albert ULg et al

Poster (2005)

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See detailThe accuracy of perceptual memory for personally known faces
Devue, Christel ULg; Brédart, Serge ULg

Poster (2005)

Recently, Ge et al. (2003) reported a very high accuracy of memory for a highly familiar face. Their Chinese participants had to identify the most veridical appearance of Mao’s face among unaltered and ... [more ▼]

Recently, Ge et al. (2003) reported a very high accuracy of memory for a highly familiar face. Their Chinese participants had to identify the most veridical appearance of Mao’s face among unaltered and transformed (inter-ocular distance was gradually increased or decreased) versions of his portrait. In the present experiment, the same facial transformations were applied to our participants’ faces to evaluate whether this hyperfidelity for familiar faces is specific to famous individuals whose face is mainly known from a standard portrait or if it could generalise to personally known faces (the own face and a close person’s face). Results showed that performance was not different for the two familiar faces in the recognition task, or between the recognition task and a perceptual discrimination task. The high accuracy of memory previously shown for a very famous face generalises to personally known individuals for whom we have a various visual experience. [less ▲]

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See detailVariability of the gas transfer velocity of CO2 in a macrotidal estuary (The Scheldt)
Borges, Alberto ULg; Vanderborght, Jean-Pierre; Schiettecatte, Laure-Sophie et al

Poster (2005)

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See detailBeyond deforestation: use of landscape metrics and satellite imagery to analyze tropical forest fragmentation
Colson, F; Shimabukuro, Y E; Bogaert, Jan ULg et al

Poster (2005)

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See detailNon destructive in-depth profile analysis of ancient patina. A necessary step for understanding their history.
Mathis, François ULg; Aucouturier, Marc; Descamps, Sophie et al

Poster (2005)

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See detailTestosterone rapidly increases the volume of the medial preoptic nucleus in male Japanese quail
Charlier, Thierry ULg; Ball, Gregory F.; Balthazart, Jacques ULg

Poster (2005)

In many vertebrate species, testosterone (T) influences the volume and cellular characteristics of a variety steroid-dependent nuclei, including the medial preoptic nucleus (POM) of male Japanese quail ... [more ▼]

In many vertebrate species, testosterone (T) influences the volume and cellular characteristics of a variety steroid-dependent nuclei, including the medial preoptic nucleus (POM) of male Japanese quail. The quail POM is a key nucleus in the control of male sexual behavior and exhibits a sex difference (larger in males than in females). In castrated quail, the POM volume is markedly increased by T but previous studies always assessed this effect after a period of 8-14 days and its specific time-course is unknown. We recently reported that antisense treatments suppressing steroid receptor coactivator-1 expression block T effects on POM volume but when treatment was discontinued, a significant increase of POM size occurred within two days. We therefore asked whether this rapid neuroanatomical change was specifically linked to the SCR-1 modulation or reflected the normal rate of T-induced effects. We collected brains from castrated male quail after 1, 2, 8 and 15 days of T treatment (CX+T) while in untreated castrates (CX) brains were collected after 1 or 15 days. The POM volume defined by Nissl staining increased in a time-dependent fashion in CX+T to reach a 40% increase after 15 days while no change was observed in CX. An increase in the average POM volume was detected on day 1 (13%) and this increase was statistically significant (25%) after only 2 days of exposure to T. No volume change was observed in the steroid-insensitive nucleus rotundus. The activation of male sexual behavior was positively correlated with the increase in POM volume. Because new neurons are not incorporated in the adult avian hypothalamus, these rapid volumetric changes must reflect increases in soma size, neuropile or extracellular space. The mechanisms underlying this unexpectedly rapid neural plasticity are currently under study, focusing in particular on the potential modifications of the steroid sensitive aromatase expressing cells. [less ▲]

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See detailEffect of potential drugs on model membranes - An AFM study
Eeman, Marc; Deleu, Magali ULg; Paquot, Michel ULg et al

Poster (2005)

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See detailThe deep impact campaign at ESO: the gas component
Rauer, H.; Jehin, Emmanuel ULg; Manfroid, Jean ULg et al

Poster (2005)

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See detailLEAFY expression and temporal sequence of floral transition in Sinapis alba L.
Bonhomme, Delphine ULg; Périlleux, Claire ULg

Poster (2005)

The shoot apical meristem (SAM) of Sinapis alba can be switched from vegetative to reproductive fate by exposure of 2-month old plants to a single long day (LD). Floral transition then occurs in good ... [more ▼]

The shoot apical meristem (SAM) of Sinapis alba can be switched from vegetative to reproductive fate by exposure of 2-month old plants to a single long day (LD). Floral transition then occurs in good synchrony within a population, and a number of biochemical, cellular, and morphological changes have been described. Our aim is to integrate gene expression patterns into this timing. We report here the analysis of SaLFY, orthologous to the floral meristem identity gene LEAFY of Arabidopsis. Materials and Methods: Plants of Sinapis were grown in 8-h shorts days for two months before being induced to flower by one 22-h LD. Shoot apices were harvested 24, 32, 40, 48, 56 and 80h after start of the LD, and prepared for in situ hybridization (Melzer et al., 1999). Results and Conclusions: As expected, the expression of SaLFY was very strong in flower primordia. More surprisingly, SaLFY was expressed well before the initiation of flowers. First, a strong signal was detected in the tip of young leaf primordia of vegetative plants. Secondly, SaLFY was transiently expressed in the SAM of induced plants, from 32h after the start of the LD, when cell proliferation increased. The signal formed, in transverse sections, a discontinuous ring with activation where last leaves were to be initiated. Interestingly, this activation in the SAM matched in time and space early growth changes previously described during the transition to flowering, namely an increase of leaf primordia growth and an acceleration of last leaf initiation (Bernier, 1997), suggesting that SaLFY may have dual functions in fate specification during the floral transition of the SAM. References: Bernier G 1997. J Exp Bot 48; 1071-1077. Melzer S, Kampmann G, Chandler J, Apel K 1999. Plant J 18; 395-405. [less ▲]

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See detailPreliminary results on the biogeochemistry in the Mekong estuary and delta (Vietnam)
Borges, Alberto ULg; Koné; Schiettecatte, L. S. et al

Poster (2005)

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See detailAbnormalities of smooth muscles in human GI motility disorders revealed by novel immunomarkers
Wedel, Theo; van Eys, G.; Glénisson, Wendy et al

Poster (2005)

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See detailDiagnostic de l'intoxication aiguë par les insecticides organophosphorés basés sur la détermination de l'activité cholinestérasique
Turcant, A.; Dehon, B.; Ganière-Monteil, C. et al

Poster (2005)

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See detailSYNOVIOCYTES BUT NOT ARTICULAR CHONDROCYTES RELEASE FREE RADICALS AFTER REPETITIVE CYCLES OF ANOXIA/REOXYGENATION: AN ELECTRON SPIN RESONANCE STUDY.
Schneider, Nicole ULg; Lejeune, Jean-Philippe ULg; Mouithys-Mickalad, Ange ULg et al

Poster (2005)

Objective : We investigated if short recurrent periods of anoxia/reoxygenation (A/R), mimicking the in vivo conditions of hypoxia, could stimulate the production of free radicals by synoviocytes and ... [more ▼]

Objective : We investigated if short recurrent periods of anoxia/reoxygenation (A/R), mimicking the in vivo conditions of hypoxia, could stimulate the production of free radicals by synoviocytes and chondrocytes. Material and Methods : Synoviocytes (immortalised rabbit line HIG-82 and equine synoviocytes isolated from synovial membranes of the stifle joint) and chondrocytes (isolated from the same equine joint) were cultured for 48 hours. The respiration rate of the cells (107 cells/assay) was studied by oxymetry and the free radical production monitored by electron spin resonance (ESR) in the presence of the spin trap (-[-4-pyridyl 1-oxide]-N-tert butyl nitrone)/ethanol mixture (2%v/v). The A/R consisted of three periods of 20 minutes anoxia, each anoxia period being followed by re-oxygenation. Oxygen consumption by the cells was measured before starting the anoxia/reoxygenation cycles and after each reoxygenation. At the end of the last A/R period, the cells were transferred into the ESR flat cell and in the cavity, and the free radical formation was monitored. Results : The equine chondrocytes showed a low respiration rate, weakly affected by A/R and no production of free radicals (n=3). Synoviocytes showed a higher respiration rate (at least 20 times higher) which was affected by recurrent A/R (decrease of the slope of oxygen consumption), and a free radical production as evidenced by the appearance of the 4-POBN/EtOH adducts (n=6). Conclusions :These observations suggest that synoviocytes, but not chondrocytes, responded to repeated anoxia-reoxygenation conditions by the production of free radicals. Synoviocytes could thus be responsible for the production of free radicals in the joints, what could be an important factor in the onset of osteoarthritis. [less ▲]

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See detailModulatory function of the H3 histaminergic receptor system in addiction: an example with cocaine and ethanol
Brabant, Christian ULg; Didone, Vincent ULg; Tirelli, Ezio ULg et al

Poster (2005)

The histaminergic neurotransmission is involved in many biological functions, including the modulation of arousal, fluid balance, food intake, reinforcement and learning. Recently, the results of several ... [more ▼]

The histaminergic neurotransmission is involved in many biological functions, including the modulation of arousal, fluid balance, food intake, reinforcement and learning. Recently, the results of several studies have also suggested that the central histaminergic system, and particularly the H3 receptors, plays a role in drug addiction. For example, in animal experiments, the administration of H3 agonists and antagonists modulate the self-administration of various drugs including cocaine, amphetamine and alcohol. In the present studies, we used the locomotor stimulant effects of drugs as an index of their abuse potential (most of addictive drugs stimulate locomotor activity, at least at some doses, and this effect is often considered as an intrinsic feature of drug addiction). In two independent experiments, we tested the effects of thioperamide, a histamine H3 antagonist/inverse agonist, on the locomotor stimulant effects of cocaine and ethanol. Our results show that thioperamide modulates the locomotor stimulant effects of both cocaine and ethanol. However, this modulatory effect was surprisingly opposite in direction depending upon the tested drug. Whereas thioperamide potentiated the locomotor stimulant effect of cocaine, it prevented the hyperactivity induced by 2 g/kg ethanol in mice. In the brain, H3 receptors is both a histamine autoreceptor modulating the synaptic release of histamine and a heteroreceptor that modulates the release of other neurotransmitters such as dopamine, acetylcholine and GABA. It is therefore likely that the modulatory action of thioperamide on cocaine and ethanol stimulant effects involves different neurotransmitter system. This conclusion is supported by our preliminary results on knock-out mice genetically devoid of histamine. In such knock-out mice, ethanol retains its stimulant properties, suggesting that histamine release is not involved in this effect. In contrast, these knock-out mice showed a reduced cocaine-induced hyperactivity, indicating that histamine release play a significant role in the stimulant effect of cocaine. [less ▲]

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See detailEtude du processus constitutif de la parentification
Haxhe, Stéphanie ULg

Poster (2005)

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See detailSound-producing apparatus of the snake-blenny Ophidion barbatum
Fontenelle, Nicolas; Henrist, Catherine ULg; Cloots, Rudi ULg et al

Poster (2005)

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See detailEcological and pathological factors related to trace metal concentrations in harbour seal Phoca vitulina in the North Sea
Drouguet, Olivier; Siebert, Ursula; Jauniaux, Thierry ULg et al

Poster (2005)

During the last decade, recurrent epizootics have affected harbour seal (Phoca vitulina) populations in the North Sea. Recent data on their trophic habits and pollutant levels are of primary importance ... [more ▼]

During the last decade, recurrent epizootics have affected harbour seal (Phoca vitulina) populations in the North Sea. Recent data on their trophic habits and pollutant levels are of primary importance for their conservation. As isotopic composition of an animal is related to that of its prey, δ13C and δ15N were measured by mass spectrometry in the muscles of 66 harbour seals beached along the coasts of France (n = 10), Belgium (n = 30) and Netherlands (n = 26) between 1994 and 2004. Trace metals concentrations (Zn, Cu, Fe, Cd, Hg and Se) were also determined in liver, kidney and muscles by Inducted Plasma Spectrometry. δ13C and δ15N values remained similar between harbour seals from France (-15.7 0/00; 18.7 0/00, respectively), Belgium (-15.7 0/00; 19.0 0/00, respectively) and Netherlands (-14.7 0/00; 18.7 0/00, respectively). These data are in good agreement with their coastal and piscivorous life style. Isotopic value remained similar between males and females and between body conditions. Hg levels were significantly higher in seals from the southern North Sea when compared to previously published data from seals collected in Norway, probably due some geographical differential exposure. Hepatic Hg was positively correlated to hepatic Se, both increasing with the length of the seals. Such a relationship reflected an age accumulation process coupled to a detoxication mechanism involving antagonism between Hg and Se in the liver. No relationship between stable isotopes and Hg and Cd levels was observed. Increasing Zn and Hg hepatic levels were observed with degrading body condition of the harbour seals, which is reflected by decreasing blubber thickness and high hepatic to total body mass ratio. These observations tend to indicate a global redistribution of trace metals from muscle and blubber to liver, as a result of protein and lipid catabolism linked to disease and starvation. [less ▲]

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See detailStable isotopes and mercury in blood of harbour seals (Phoca vitulina) caught on a German sandbank
Di-Poi, C.; Siebert, Ursula; Drouguet, Olivier et al

Poster (2005)

More than 21 500 harbour seals were killed by Phocine Distempter Virus in the North Sea and adjacent waters in 2002. After the second seal die-off had ceased, seals were captured alive (and then released ... [more ▼]

More than 21 500 harbour seals were killed by Phocine Distempter Virus in the North Sea and adjacent waters in 2002. After the second seal die-off had ceased, seals were captured alive (and then released) on a sandbank (Schleswig-Holstein, Germany) for health and ecotoxicological investigations. Stable carbon and nitrogen ratios (δ13C and δ15N) were measured by mass spectrometry in clotted blood cells of 24 harbour seals captured between 2002 and 2003. Total mercury (Hg) concentrations were determined by spectrometric absorption in the whole blood of 8 harbour seals and compared to the Hg level measured in blood from 8 seals found stranded along the southern North Sea coast. The average isotopic composition measured in the blood cells was –15.6 ± 0.3 0/00 and 18.7 ± 0.6 0/00 for δ13C and δ15N respectively, similar to that obtained previously in muscle of stranded individuals, confirming the high position of the harbour seal in the trophic food chain. δ13C and δ15N values did not differ significantly between seals caught in November 2002, April 2003 and September 2003 suggesting similar diet throughout these 3 periods. The average concentration of mercury in whole blood of living and stranded harbour seals did not differ significantly (94 ± 41 vs 146 ± 71 µg.l-1 respectively). No biological parameters (weight, length, age status and stable isotopes ratios) seemed to influence these concentrations. Blood is known to reflect recent exposure to mercury through the diet. These preliminary results suggest that blood is an interesting substrate for both trophic studies and pollutant long-term monitoring of the harbour seal in the North Sea. [less ▲]

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See detailTechnique of mural paintings from the Tournai Cathedral
Lepot, Laurent ULg; Denoël, Sophie; Gilbert, Bernard ULg

Poster (2005)

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See detailMOTOR UNIT INVOLVEMENT IN PLS, ALS AND KENNEDY’S DISEASE
WANG, François-Charles ULg; Le Forestier, Nadine; GERARD, Pascale ULg et al

Poster (2005)

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See detailDéveloppement d’indicateurs alternatifs de la fertilité femelle chez les bovins laitiers. Applications à la cartographie fine de QTL
Guillaume, F.; Ben-Jemaa, S.; Fritz, S. et al

Poster (2005)

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See detailBiological control of Psoroptes ovis using entomopathogenic fungi
Lekimme, M.; Mignon, Bernard ULg; Focant, C. et al

Poster (2005)

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See detailIn vitro activity of Beauveria bassiana against Psoroptes ovis
Lekimme, M.; Mignon, Bernard ULg; Focant, C. et al

Poster (2005)

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See detailA case of sylvatic dermatophytosis due to Trichophyton mentagrophytes in a cat
Carlotti, D.-N.; De Barbeyrac, P.; Mignon, Bernard ULg et al

Poster (2005)

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See detailAn improved ELISA technique for the diagnosis of Psoroptes ovis infestations in cattle
Lonneux, J. F.; Mignon, Bernard ULg; Bossaert, K. et al

Poster (2005)

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See detailHemolytic activity of new linear surfactin analogs
Dufour, Samuel; Deleu, Magali ULg; Wathelet, Bernard ULg et al

Poster (2005)

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See detailLinearity and stationarity of the pharmacokinetics of tiludronate in horses
Delguste, Catherine ULg; Doucet, Michèle; Amory, Hélène ULg et al

Poster (2005)

Two studies were conducted in order to assess the linearity and stationarity of the pharmacokinetics of tiludronate in horses. For each study, plasma concentrations of tiludronate were measured by HPLC-UV ... [more ▼]

Two studies were conducted in order to assess the linearity and stationarity of the pharmacokinetics of tiludronate in horses. For each study, plasma concentrations of tiludronate were measured by HPLC-UV at regular intervals and noncompartmental analysis was performed. First, single intravenous administrations of 0.05 (group 1, n = 5), 0.1 (group 2, n = 5) and 0.2 mg/kg (group 3, n = 5) were performed in healthy male adult horses. A linear relationship between groups was found for C5min (C5min = 0.0726 + 11.8589 * dose) as well as for AUC0-inf (AUC0-inf = -0.632561 + 30.9649 * dose). Clearance ranged from 0.033 to 0.044 L/h/kg and was not significantly different between groups. MRT (h) were 3.96, 4.95 and 9.40 and VDss (L/kg) were 0.16, 0.19 and 0.28 for the 0.05, 0.1 and 0.2 mg/kg doses respectively. Second, 10 daily intravenous administrations at a dosage rate of 0.1 mg/kg were administered to 4 healthy horses. Plasma tiludronate concentrations were measured after the 1st and 10th dose as well as 8 hours after each dose. The mean plasma accumulation ratio between the 1st and the 10th dose was 1.31 ± 0.48. Medians of the tiludronate concentration values measured in plasma 8 hours post-dose were not statistically different between doses. Maximum and minimum concentrations of tiludronate (mg/L) following the last dose were 0.91 and 0.04 respectively. It was concluded that the pharmacokinetics of tiludronate in horses are linear from 0.05 to 0.2 mg/kg IV and stationary after 10 IV administrations of 0.1 mg/kg. [less ▲]

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See detailEstimated energy balance in the jovian upper atmosphere during an auroral heating event
Melin, H.; Miller, S.; Stallard, T. et al

Poster (2005)

We present an analysis of a series of observations of the auroral/polar regions of Jupiter, carried out between September 8 and 11, 1998, making use of the high-resolution spectrometer, CSHELL, on the ... [more ▼]

We present an analysis of a series of observations of the auroral/polar regions of Jupiter, carried out between September 8 and 11, 1998, making use of the high-resolution spectrometer, CSHELL, on the NASA InfraRed Telescope Facility (IRTF), Mauna Kea, Hawaii; these observations spanned an ``auroral heating event". This analysis combines the measured line intensities and ion velocities with a one-dimensional model of the jovian thermosphere/ionosphere (Grodent et al. 2001). We compute the model line intensities both assuming local thermodynamic equilibrium (LTE) and, relaxing this condition (non-LTE), through detailed balance calculations (Oka et al. 2004), in order to compare with the observations. Taking the model parameters derived, we calculate the changes in heating rate required to account for the modeled temperature profiles that are consistent with the measured line intensities. Comparison of the various heating and cooling terms enables us to investigate the balance of energy inputs into the auroral/polar atmosphere. Increases in Joule heating and ion drag are sufficient to explain the observed heating of the atmosphere; increased particle precipitation makes only a minor heating contribution. But local cooling effects - predominantly H[SUB]3[SUP]+[/SUP][/SUB] radiation-to-space - are shown to be too inefficient to allow the atmosphere to relax back to pre-event thermal conditions. Thus we conclude that this event provides observational, i.e. empirical, evidence that heat must be transported away from the auroral/polar regions by thermally or mechanically driven winds. [less ▲]

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See detailMolecular investigation to identity of phytoplasma associated with pear and apricot trees in Tunisia
Aldaghi, M.; Kummert, J.; Roussel, S. et al

Poster (2005)

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See detailSelection of antagonists against Penicillium expansum and Botrytis cinerea, two post harvest apple parasites
Achbani, E. H.; Mounir, R.; El Jaafari, S. et al

Poster (2005)

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See detailDevelopment of molecular tests for simultaneous detection of Erwinias spp infecting potato tubers in Belgium
Moh, Ahoussi Augustin ULg; Roussel, S.; Van mellaert, S. et al

Poster (2005)

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Peer Reviewed
See detailEstimation of (co)variance components across breeds by a test-day model adapted to New Zealand dairy cattle.
Vanderick, Sylvie ULg; Harris, Bevin; Mayeres, Patrick et al

Poster (2005)

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Peer Reviewed
See detailMercury, polychlorobiphenyls and stable isotopes in the blood of harbour seals (Phoca vitulina) from the southern North Sea
Das, Krishna ULg; Lepoint, Gilles ULg; Fonfara, Sonja et al

Poster (2005)

The harbor seal (Phoca vitulina) is one of the most widely distributed seal species and the North Sea contains around 10 % of the world population. The harbour seal population in the North Sea was ... [more ▼]

The harbor seal (Phoca vitulina) is one of the most widely distributed seal species and the North Sea contains around 10 % of the world population. The harbour seal population in the North Sea was estimated at 36 000 individuals between 1994 and 1996). However, recurrent Phocine Distemper Virus (PDV) epizooties have affected the North Sea seal population. Recently, 21 500 harbor seals were killed by PDV in the North Sea and adjacent waters in 2002. Some intriguing questions about the interaction between PDV and immunotoxic contaminants, such as mercury (Hg) and polychlorinated biphenyls (PCBs) remain unanswered. In this framework, circulating levels of Hg and PCBs (PCBs 28, 52, 101, 118, 138, 153, 180) were measured in the blood of 24 harbour seals captured on a sandbank between 2001 and 2004 (Schleswig-Holstein, Germany). As pollutant level may be linked to the trophic position in the food web, carbon and nitrogen isotopic ratios (δ13C and δ15N) were measured in clotted blood cells. The average concentration of mercury in these living seals did not differ significantly from those observed previously in stranded harbour seals (94 ± 41 vs 146 ± 71 µg.l-1 respectively). Mean blood concentrations of total PCBs (∑PCBs) were 11 ng/ml. CB 153 clearly dominated the mix (45%) followed by PCB 138 (31%). The average isotopic composition measured in the blood cells was –15.6 ± 0.3 0/00 and 18.7 ± 0.6 0/00 for δ13C and δ15N respectively, similar to that obtained previously in muscle of stranded individuals, confirming the high position of the harbour seal in the North Sea trophic chain. Further investigations are obviously needed on a larger sampling but our preliminary results suggest that blood is an interesting substrate for both trophic and pollutant long-term monitoring of the harbour seal in the North Sea. [less ▲]

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See detailPhylogeography of Harbour Porpoise (Phocoena phocoena) in the Eastern North Atlantic and in the Black Sea Explored by the Analyses of Nuclear and Mitochondrial DNA
Fontaine, Michaël; Baird, C.; Stuart, J. E. et al

Poster (2005)

Study of the genetic population structure and the demographic history of the harbour porpoise (Phocoena phocoena) has been nearly comprehensive throughout its distribution in North Atlantic, most studies ... [more ▼]

Study of the genetic population structure and the demographic history of the harbour porpoise (Phocoena phocoena) has been nearly comprehensive throughout its distribution in North Atlantic, most studies using the mitochondrial control region as a genetic marker. Although these studies have shown population structure in some parts of the North Atlantic, mitochondrial DNA is a single, maternally inherited locus and therefore insufficient to fully characterize population structure and history. Polymorphism at 11 microsatellite loci was analyzed in harbour porpoises collected throughout the range of the species in the Central and Eastern North Atlantic from the Iberian peninsula northward to Arctic waters (Portugal, Spain, bay of Biscay, Irish waters, English Channel, the southern bay of the North Sea, Norway, Faroe Islands, and Iceland) and also along the coasts of the Black Sea (Turkey, Ukraine, Bulgaria and Georgia). Multilocus tests for allele frequency differences and population structure estimates indicate complete genetic isolation between Atlantic and Black Sea porpoises. No fine population structure was observed within the Black Sea, and this population displayed a low genetic diversity compared to those of Atlantic. These results can be interpreted in the light of the demographic history of this relict population and the strong founder effect and bottleneck it may have undergone in its past evolution. In Eastern North Atlantic waters, microsatellite data revealed fine scale partitioning of the genetic variation. These results will be compared to the pattern previously reported based on the analysis of the mtDNA control region, and seem to correlate with variation in oceanographic features. [less ▲]

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See detailEvaluation of food born lactic acid bacteria for their use as protective cultures in food
Dortu, C.; Thonart, Philippe ULg

Poster (2004, December 17)

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See detailDiscovery of non-biodegradable fossil cellulose.
Lechien, V.; Rodriguez, Ch.; Grandjean, Jean ULg et al

Poster (2004, December 17)

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See detailStudy of a novel elicitor produced by Pseudomonas putida BTP1 in the ISR on bean
Jourdan, Emmanuel ULg; Ongena, Marc ULg; Schaffer, M. et al

Poster (2004, December 17)

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See detailSaturn's UV Aurora Imaged with HST during the Cassini Approach to Saturn
Clarke, J. T.; Gérard, Jean-Claude ULg; Grodent, Denis ULg et al

Poster (2004, December 13)

A series of HST STIS UV images of Saturn's aurora were obtained on 13 days in Jan. 2004 as the Cassini spacecraft measured the approaching solar wind properties. Clear general correlations have been found ... [more ▼]

A series of HST STIS UV images of Saturn's aurora were obtained on 13 days in Jan. 2004 as the Cassini spacecraft measured the approaching solar wind properties. Clear general correlations have been found between the auroral power and a) Saturn's kilometric radiation, and b) the solar wind dynamic pressure, but not with the direction of the interplanetary magnetic field. While these general correlations are now well established, a closer examination of the data raises many interesting questions. Saturn's auroral emissions exhibit both local time and co-rotational properties, the auroral oval does not appear centered on the magnetic and rotational pole, the auroral emissions exhibit large and unexpected motions in latitude with time and/or planetary rotation, and the auroral oval does not appear continuous, but broken with longitude. This talk will present a more detailed look at Saturn's aurora from the HST images, with a comparison of auroral emission properties to those at the Earth and Jupiter. [less ▲]

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