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See detailDimebon Enhances Hippocampus-Dependent Learning in Mouse Models of Appetitive Y-Maze and Inhibitory Step-Down Memory Tasks in Mice
Vignisse, Julie ULg; Steinbusch, Harry W.M.; Bolkunov, Alexei et al

Poster (2011, February 23)

Dimebon, a compound recently proposed for a treatment of Alzheimer’s disorder, was suggested to have memory enhancing properties in pre-clinical and clinical studies. We investigated whether dimebon at ... [more ▼]

Dimebon, a compound recently proposed for a treatment of Alzheimer’s disorder, was suggested to have memory enhancing properties in pre-clinical and clinical studies. We investigated whether dimebon at doses acutely (0.1 mg/kg and 0.5 mg/kg) or repeatedly (0.1 mg/kg) administered to mice via i.p. injections, increases memory scores respectively in an appetitive and an inhibitory learning task. Acute treatment with dimebon at the dose 0.1 mg/kg did not affect learning scores in 3-month-old C57BL/6N. Acute treatment with higher dose of dimebon (0.5mg/kg) was found to enhance inhibitory learning in 3-month-old mice as shown in the step-down avoidance paradigm in C57BL/6N mice. In a model of appetitive learning, a spatial version of the Y-maze, repeated treatment with dimebon increased the rate of correct choices and decreased the latency of accessing a water reward after water deprivation. Repeated administration of dimebon also increased the duration of drinking behaviour during training/testing procedures although water consumption behaviour was not altered. Additional behavioural tests were carried out to investigate possible non-specific effects of dimebon on parameters of drinking, anxiety and exploration/locomotion. Our data suggest that dimebon enhances hippocampus-dependent learning in both appetitive and inhibitory tasks in mice. [less ▲]

Detailed reference viewed: 48 (5 ULg)
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See detailHistone deacetylase 5 is a regulator of S phase progression
Peixoto, Paul ULg; Pirotte, Sophie ULg; Matheus, Nicolas ULg et al

Poster (2011, February 05)

Detailed reference viewed: 17 (5 ULg)
See detailFading of modern Prussian blue pigments in linseed oil medium
Samain, Louise ULg; Silversmit, Geert; Sanyova, Jana et al

Poster (2011, February 04)

Detailed reference viewed: 22 (6 ULg)
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See detailMiR-146a an angiostatic miRNA elevated in peripartum cardiomyopathy
Halkein, Julie ULg; Castermans, Karolien; Malvaux, Ludovic et al

Poster (2011, February)

Detailed reference viewed: 13 (4 ULg)
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See detailMiR-146a: an angiostatic miRNA with tumor-suppressive properties
Halkein, Julie ULg; Bovy, Nicolas ULg; Castermans, Karolien et al

Poster (2011, February)

Detailed reference viewed: 22 (7 ULg)
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See detailALT "4"CER "Alternatives for cereals"
Delcour, Alice ULg; Van Stappen, Florence ULg

Poster (2011, February)

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See detailL'adolescience, un univers de contradictions
Vanesse, Marc ULg; Colmant, François ULg; Colson, Justine ULg et al

Poster (2011, February)

Un documentaire produit par le Lemme (Laboratoire d'étude sur les médias et la médiation) et réalisé dans cinq écoles au cours duquel des adolescents parlent librement de leurs rapports avec les sciences.

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See detailA collection of polar cyanobacteria to contribute to the inventory of the biodiversity and discover the biotechnological potential
Wilmotte, Annick ULg; Waleron, Kzryzstof; Waleron, Malgorzata et al

Poster (2011, February)

Detailed reference viewed: 21 (7 ULg)
Peer Reviewed
See detailmicroRNA-21 Exhibits Anti-Angiogenic Function by Targeting RhoB Expression in Endothelial Cells
Sabatel, Céline; Malvaux, Ludovic; Bovy, Nicolas ULg et al

Poster (2011, February)

Detailed reference viewed: 12 (3 ULg)
See detailDriven weak to strong pinning crossover in a partially nanopatterned superconductor
Shaw, Gorky ULg; Sinha, Jaivardhan; Mohan, Shyam et al

Poster (2011, February)

Detailed reference viewed: 10 (1 ULg)
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See detailDoppler Echocardiographic follow up of three horses with congestive heart failure and treated with quinapril, digoxin, and diuretics
Leroux, Aurélia ULg; Sandersen, Charlotte ULg; Borde, Laura ULg et al

Poster (2011, February)

Angiotensin converting enzyme inhibitors are recommended therapy in human and canine patients with congestive heart failure (CHF), but little is known concerning their efficiency to treat horses with CHF ... [more ▼]

Angiotensin converting enzyme inhibitors are recommended therapy in human and canine patients with congestive heart failure (CHF), but little is known concerning their efficiency to treat horses with CHF. Enalapril has been shown to be poorly absorbed in horses and quinapril has been shown to decrease the severity of the insufficiency and to increase the stroke volume (SV) and the cardiac output (CO) in horses with mitral regurgitation (MR) without signs of CHF. The objective of this cases report was to evaluate the effect of quinapril associated with routine treatment in horses with CHF. Three horses with clinical, echocardiographic and electrocardiographic signs of severe MR, CHF and secondary atrial fibrillation were studied (Fig 1 to 3). None of them had been previously treated for those problems. According to the ACVIM classification system for management of canine CHF, they were therefore classified in class C. They were treated with quinapril 0.2mg/kg SID PO, digoxin 0.011mg/kg BID PO, and furosemide 1mg/kg BID IM. Standard echocardiographic and Doppler measurements were performed before treatment (T0), and 1 and 4 weeks after starting treatment (W1 and W4, respectively). All horses showed a transient clinical improvement (decrease of edemas and disappearance of the dyspnea) after 1 week of treatment, but clinical signs deteriorated within the following weeks in 2 horses that were euthanized for ethical reasons. The third horse kept a steady clinical status and was discharged with the treatment pursued at home. Evolution (in %) of main echocardiographic parameters at W1 and W4 compared to T0 values are showed in Table1. Large individual variations in response to the treatment were seen. Nevertheless, in all horses, a decrease of the Heart Rate (HR) was observed after 1 week of treatment, but the HR increased again after 1 month of treatment (Fig 4). On the contrary, no increase in SV or CO, and no decrease in LVIDd were seen in response to treatment (Fig 5). In the 2 horses that were euthanized, the fractional shortening (FS) and the pre-ejection to ejection time ratio (PEP/ET) decreased and the mitral E peak velocity increased with treatment, whereas they followed the opposite evolution in the surviving horse. No conclusion can be drawn from this study because of the limited number of studied cases. However, it would be interesting to extend it to additional cases and to less severely affected cases (i.e. horses classified in class C after initial treatment or class B horses). Negative chronotropic effect of digoxin was suggested after 1 week of treatment since a decrease of the HR was observed in all horses. However, this effect seemed to decrease after 1 month of treatment. Those preliminary results of echocardiography suggest that quinapril in association with digoxin and furosemide at the used dosage could be inefficient to reduce the left ventricular filling pressure and to improve the myocardial contractility in horses with severe CHF. This could however be due to the fact that the 3 studied horses were cases refractory to classic treatment (thus to be classified in class D). [less ▲]

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See detailNucleolar structure across evolution : the transition between bi- and tricompartmentalized nucleoli lies within the class Reptilia
Franck, Claire; Lamaye, Françoise; Thelen, Nicolas ULg et al

Poster (2011, January 31)

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See detailDimebon enhances hippocampus-dependent learning in both appetitive and inhibitory memory tasks in mice
Vignisse, Julie ULg; Steinbusch, Harry W.M.; Bolkunov, Alexei et al

Poster (2011, January 31)

Dimebon, a compound recently proposed for a treatment of Alzheimer’s disorder was suggested to have memory enhancing properties in pre-clinical and clinical studies. We investigated whether dimebon at ... [more ▼]

Dimebon, a compound recently proposed for a treatment of Alzheimer’s disorder was suggested to have memory enhancing properties in pre-clinical and clinical studies. We investigated whether dimebon at doses acutely (0.1 mg/kg and 0.5 mg/kg) or repeatedly (0.1 mg/kg) administered to mice via i.p. injections, increases memory scores respectively in an appetitive and an inhibitory learning task. Acute treatment with dimebon at the dose 0.1 mg/kg did not affect learning scores in either 3-month-old C57BL/6N or CD1 mice. Acute treatment with higher dose of dimebon (0.5mg/kg) was found to enhance inhibitory learning in 3- and 7-month-old mice as shown in the step-down avoidance paradigm in C57BL/6N mice. No effects on learning were seen in CD1 mice. In a model of appetitive learning, a spatial version of the Y-maze, repeated treatment with dimebon increased the rate of correct choices and decreased the latency of accessing a water reward after water deprivation. Repeated administration of dimebon also increased the duration of drinking behaviour during training/testing procedures although behaviours in others tests or water consumption were not altered. Acute treatment of water-deprived and non-water-deprived mice with dimebon also did not affect their water intake. Our data suggest that dimebon enhances hippocampus-dependent learning in both appetitive and inhibitory tasks in mice. [less ▲]

Detailed reference viewed: 12 (3 ULg)
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See detailEffect of kynurenic acid on sensitivity to cortical spreading depression in rats
Chauvel, Virginie ULg; Vamos, Eniko; Pardutz, Arpat et al

Poster (2011, January 31)

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See detailSpatio-temporal localisation of β-actin and γ-actin isoforms during the development of the organ of Corti in rat from the embryonic day 18 (E18) to the post-natal day 25 (P25).
Johnen, Nicolas ULg; Thelen, Nicolas ULg; Cloes, Marie ULg et al

Poster (2011, January 31)

The auditory organ, the organ of Corti (OC), is a highly specialized structure composed by specific cellular types. The sensory cells (HC) are characterized by stereocilia at their apex and are necessary ... [more ▼]

The auditory organ, the organ of Corti (OC), is a highly specialized structure composed by specific cellular types. The sensory cells (HC) are characterized by stereocilia at their apex and are necessary for the sound perception. Theses cells are supported by supporting cells. Based on their morphology and physiology, at least four types of supporting cells can be identified in the OC: inner and outer pillar cells (PC), phalangeal cell and Deiter’s cells. Sensory and supporting cells have cytoskeletons containing β-actin and γ-actin isoforms. In the adult mammalian cochlea, amounts of γ-actin increase and β-actin decrease in the order: outer pillar cells, inner pillar cells, Deiters’ cells and hair cells. In sensory cells, γ-actin appears to be the most prominent component with an apparent γ-actin/β-actin ratio of approximately 2:1 (Hofer et al., 1997). β-actin is present in the cuticular plate but is more concentrated in the stereocilia, especially at the base where the stereocilia insert into the cuticular plate. The amount of γ-actin differs less between these structures, the stereocilia and cuticular plate, although its expression is apparently higher towards the tip of stereocilia and it is the predominant isoform of the hair cell's lateral wall (Furness et al., 2005). The differential subcellular localization of two actin isoforms suggests they may play different functions in auditory organ. In the brain, β-actin is restricted to dynamic structures whereas γ-actin is more ubiquitously distributed and occurs in relatively quiescent regions (Micheva et al., 1998). In the present study, by using confocal microscopy, we investigated the spatio-temporal localisation of β-actin and γ-actin isoforms during the development of the OC in rat from the embryonic day 18 (E18) to the post-natal day 25 (P25). Our results indicated that the labelling for both actin isoforms changed during the OC development. Between E18 and P25, we observed a labelling for β-actin in the apical region of the HC. Between P8 and P25, the feet of PC are also β-actin-positive. Unlike β-actin, between E18 and P10, γ-actin is detected in the basal region of supporting cells. Between P12 and P25, the labelling for γ-actin is preferentially localized in the apical surface of the HC. Our results revealed that during development β-actin isoform preceded γ-actin isoform in the apical region of HC. They also suggest that γ-actin isoform might be involved in attachment of supporting cells with their basal membrane and that β-actin isoform might play a role in PC reorganization during the formation of Corti tunnel. [less ▲]

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See detailDistribution of glycogen during the development of the organ of Corti
Thelen, Nicolas ULg; Cloes, Marie ULg; Johnen, Nicolas ULg et al

Poster (2011, January 31)

Although the structure of the auditory organ in mature mammals, the organ of Corti, is clearly established, its development is far from being elucidated. Using cytochemical methods at the light and ... [more ▼]

Although the structure of the auditory organ in mature mammals, the organ of Corti, is clearly established, its development is far from being elucidated. Using cytochemical methods at the light and electron microscope levels, we examined the spatiotemporal distribution of polysaccharides during the development of the organ of Corti in rats from embryonic day 16 (E16) to postnatal day 15 (P15). At E16, small polysaccharide inclusions were detected in the cytoplasm of the future inner pillar cells by electron microscope only. These inclusions became obvious at the light microscope level at E17. At E19, the polysaccharide deposits were important within the inner pillar cells and they arose in the Hensen cells cytoplasm. Polysaccharide accumulations also appeared in the outer pillar cells and the Deiters cells from P3-P4. As the organ of Corti developed, the amount of polysaccharide inclusions within the inner and outer pillar cells decreased. At P15, large amount of polysaccharide deposits were visible in the Deiters cells whereas they had almost disappeared from the inner and outer pillar cells. Finally, we showed that the polysaccharide deposits present in the developing organ of Corti are PAS-positive and can be digested with a salivary amylase, suggesting that they are essentially constituted of glycogen. [less ▲]

Detailed reference viewed: 44 (13 ULg)
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See detailNovel HDAC/DNMT Twin inhibitors interfere with angiogenesis
Shiva Shankar, Thammadihalli Veerasangaiah ULg; Sulka, Béatrice ULg; Blacher, Silvia ULg et al

Poster (2011, January 31)

DNA methylation and histone deacetylation are two key epigenetic modifications that play central role in regulation of gene expression. Several studies have shown that histone deacetylases (HDAC) and DNA ... [more ▼]

DNA methylation and histone deacetylation are two key epigenetic modifications that play central role in regulation of gene expression. Several studies have shown that histone deacetylases (HDAC) and DNA methyltransferases (DNMT) inhibitors are potent anti-angiogenic compounds. Though combination of HDAC and DNMT inhibitors are now being examined in clinical trials of hematological malignancies, little work has been done to understand the effect of this combination on physiological and tumoral angiogenesis. We have designed and tested a family of twin drugs with intrinsic HDAC and DNMT inhibitory activities in relevant models of angiogenesis in vitro (Human Umbilical Vein Endothelial Cells – HUVEC and aortic ring) and in vivo (chick chorioallantoic membrane and Zebrafish). We have identified a lead compound having quantifiable anti-angiogenic effect without cytotoxicity affecting global histone acetylation and DNA methylation levels. In order to elucidate its anti-angiogenic mechanism, we characterized gene expression pattern simultaneously with the methylation profile of HUVEC cells treated with the lead compound and reference epigenetic modulators. This approach based on parallel microarray analyses permitted us to underscore a list of genes exclusively affected by the lead compound but not by other HDAC or DNMT inhibitors. These genes were then analyzed using the Ingenuity Pathway software revealing potential involvement of a subset of genes in angiogenesis. Our present aim is to validate the expression levels of a series of genes with respect to epigenetic mechanisms (histone modifications and DNA methylation). Finally, the biological relevance of the target genes will be explored by RNA silencing. Hence, we are using these novel epigenetic modulators as a tool to understand the regulatory mechanism of angiogenesis and to develop effective approaches to treat cancer. [less ▲]

Detailed reference viewed: 97 (17 ULg)
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See detailSpatio-temporal localization of the glial fibrillary acidic protein (GFAP) in the spiral ganglion from the 16th embryonic day until the 25th postnatal day in rats
Cloes, Marie ULg; Thelen, Nicolas ULg; Johnen, Nicolas ULg et al

Poster (2011, January 31)

The spiral ganglion (SG) is responsible for the conduction of the information between the sensory epithelium of the auditory organ (the organ of Corti) and the central nervous system. The origin and ... [more ▼]

The spiral ganglion (SG) is responsible for the conduction of the information between the sensory epithelium of the auditory organ (the organ of Corti) and the central nervous system. The origin and nature of the SG glial cells in mammals are barely known, although glial cells are essential to the development and the working of the nervous system. Using confocal microscopy, we studied the spatio-temporal distribution of the GFAP in the rat SG from the 16th embryonic day (E16) until the 25th postnatal day (P25). We performed a double-labelling experiment targeting GFAP- and betaIIItubulin-positive cells. BetaIII-tubulin is used for the labelling of (pro)neural cells, according to a previous preliminary study from our team. Our first results show clearly that the GFAP is expressed in the SG from P0 until P25. A homogenous labelling is found in the cytoplasm of a few dispersed unidentified cells among the (pro)neurons, whereas a granular labelling appears among a group of cells neighbouring the bundle of fibers innervating the organ of Corti. The identity of the GFAP-positive cells will be further investigated by electron microscopy. The reason why the labelling of the GFAP adopts those two different aspects is still unknown. Moreover, it seems that, surprisingly, some cells of the ganglion are not labelled by either marker. The possibility that such cells correspond to fibroblasts will be tested thanks to the labelling of vimentin. [less ▲]

Detailed reference viewed: 58 (15 ULg)
See detailidentification of new parterns of the NOD2 protein
Lecat, Aurore ULg; Di Valentin, Emmanuel ULg; Fillet, Marianne ULg et al

Poster (2011, January 27)

Detailed reference viewed: 27 (13 ULg)
See detailRole of MDC1 in NF-kappaB activation by DNA double-strand breaks.
Sabatel, Hélène; Piette, Jacques ULg; Habraken, Yvette ULg

Poster (2011, January 25)

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See detailRespiratory pathologies in foals
Frizot, Myriam; Amory, Hélène ULg; Borde, Laura ULg et al

Poster (2011, January 22)

Detailed reference viewed: 58 (16 ULg)
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See detailTHE USE OF VAC® THERAPY IN HORSES
Lazzaretti, Sarah; Grulke, Sigrid ULg; Serteyn, Didier ULg et al

Poster (2011, January 22)

Detailed reference viewed: 58 (9 ULg)
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See detailContribution of CT scan for lesions affecting the spine
Deudon, Pauline ULg; Peeters, Dominique ULg; Balligand, Marc ULg et al

Poster (2011, January 22)

Detailed reference viewed: 37 (18 ULg)
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See detailMettalic foreign body in a horse: case report
Evrard, Laurence ULg; Bolen, Géraldine ULg; Gougnard, Alexandra ULg et al

Poster (2011, January 22)

Detailed reference viewed: 66 (28 ULg)
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See detailIdiopathic central diabetes insipidus and severe hypernatremia in a cat
Desmas, Isabelle ULg; Manens, Jefferson ULg; Rizza, Maïlis et al

Poster (2011, January 22)

Detailed reference viewed: 50 (9 ULg)
See detailStudy of the combined effect of 5-ALA-based photodynamic therapy and NF-kappaB inhibition on human glioblastoma cell survival
Coupienne, Isabelle ULg; Fettweis, Grégory ULg; Piette, Jacques ULg

Poster (2011, January)

Glioblastoma constitute the most frequent and deadliest type of brain tumors in human adults. They are very resistant to all current therapies and are associated with a huge rate of recurrence. In most ... [more ▼]

Glioblastoma constitute the most frequent and deadliest type of brain tumors in human adults. They are very resistant to all current therapies and are associated with a huge rate of recurrence. In most cases, this type of tumor is characterized by a constitutive activation of the nuclear factor-kappaB (NF-kappaB). This factor is known to be a key regulator of various physiological processes such as inflammation, immune response, cell growth or apoptosis. In the present study, we explored the role of NF-kappaB activation in the sensitivity of human glioblastoma cells to a treatment by 5-aminolevulinic acid (5-ALA)–based photodynamic therapy (PDT). Our results show that inhibition of NF-kappaB improves glioblastoma cell death in response to 5-ALA-PDT. We then studied the molecular mechanisms underlying the cell death induced by PDT combined or not with NF-kappaB inhibition. We found that PDT mainly induced necrosis in glioblastoma cells and NF-kappaB was found to have anti-necrotic functions in this context. In the second part of this study, we examined the role of the kinase RIP3, recently identified as a key effector of the necrotic pathway, in 5-ALA-PDT-induced necrosis and studied whether NF-kappaB interfered in RIP3-dependent necrosis induction. [less ▲]

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See detailPegase : Outil opérationnel de modélisation de la qualité des eaux de surface
Deliège, Jean-François ULg; Everbecq, Etienne ULg; Grard, Aline ULg et al

Poster (2011, January)

Pegase (Planification Et Gestion de l’ASsainissement des Eaux) est un modèle intégré bassins hydrographiques/rivières qui permet de calculer de façon déterministe et prévisionnelle la qualité des eaux des ... [more ▼]

Pegase (Planification Et Gestion de l’ASsainissement des Eaux) est un modèle intégré bassins hydrographiques/rivières qui permet de calculer de façon déterministe et prévisionnelle la qualité des eaux des rivières en fonction des rejets et apports de pollution (relation pression-impact), pour des situations hydrologiques constantes ou non-stationnaires. Pegase est un outil opérationnel doté d’une interface conviviale, s’interfaçant avec des outils propriétaires de type ArcGIS et permettant d’orienter les choix des opérateurs publics et privés en matière de gestion des eaux de surface à l’échelle des bassins versants. [less ▲]

Detailed reference viewed: 243 (34 ULg)
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See detailHow asteroseismology can help to precisely constrain properties of planet-host stars
Salmon, Sébastien ULg; Montalban Iglesias, Josefa ULg; Lanotte, Audrey ULg et al

Poster (2011, January)

Nowadays more than 500 exoplanets have been discovered, mainly studied by radial velocity and transit measurements. Precise knowledge on their characteristics is crucial to develop theories of planetary ... [more ▼]

Nowadays more than 500 exoplanets have been discovered, mainly studied by radial velocity and transit measurements. Precise knowledge on their characteristics is crucial to develop theories of planetary formation and evolution. In that aim, not only star and planet(s) masses but also the evolutionary stage of systems are needed. From radial velocity measurements one has to assume the inclination and the stellar mass of the system to disentangle the mass of the planet. When transit is observable, one can measure the ratio of planetary and stellar radii. Finally, the degree of evolution of the system is determined by the one of the star. Thus the host star must be well known to obtain a full set of system properties. However, determination of stellar parameters such as the mass, radius and its evolution from classical observables (Teff, log g, [Fe/H]) suffers of large uncertainties. This is particularly true for dwarf stars on the Main Sequence. Fortunately we can obtain better constrains with the help of asteroseismology. That latter approach probes the stellar properties through observation of oscillations present in stars. With the launches of high-precision photometry space missions, CoRoT and Kepler, we are now able to detect oscillations in a huge number of stars. In particular Kepler photometry, primarily intended to detect transits of planet, can give accurate stellar parameters of planetary systems as it also affords to make [less ▲]

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See detailAquapôle, Cellule Latitudes Sud : Coopération avec les pays du Sud dans le domaine de l’eau
Deliège, Jean-François ULg; Detienne, Xavier; Grard, Aline ULg et al

Poster (2011, January)

L’objectif de la Cellule Latitudes Sud au sein de l'Aquapôle de l'Université de Liège est de favoriser le développement de projets liés à l’eau dans les pays du Sud, et en particulier dans les pays en ... [more ▼]

L’objectif de la Cellule Latitudes Sud au sein de l'Aquapôle de l'Université de Liège est de favoriser le développement de projets liés à l’eau dans les pays du Sud, et en particulier dans les pays en développement. La Cellule Latitudes Sud intervient au niveau de la promotion, la réalisation et/ou la collaboration à différents projets avec une approche pluridisciplinaire et plurisectorielle. Elle s’appuie sur les compétences de l’Aquapôle (ULg) et également sur le réseau de compétences que constituent ses services membres. [less ▲]

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See detailLa thérapie institutionnelle est-elle efficace ?
Triffaux, Jean-Marc ULg

Poster (2011, January)

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See detailPyridine Derivatives of Nimesulide as New Promising Anti-inflammatory Agents
Renard, Jean-François ULg; Lecomte, Frédéric ULg; de Leval, Xavier et al

Poster (2011, January)

Detailed reference viewed: 54 (2 ULg)
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See detailCapacité à ressentir la durée du temps : instauration d'une sémiologie développementale en milieu écologique chez des enfants de 2,5 à 12 ans
SCHOLL, Jean-Marc ULg

Poster (2011, January)

Introduction : Comment le clinicien peut-il préciser la sémiologie de « la perception de l'écoulement du temps » chez l'enfant dans son contexte écologique ? En psychologie clinique la perception du temps ... [more ▼]

Introduction : Comment le clinicien peut-il préciser la sémiologie de « la perception de l'écoulement du temps » chez l'enfant dans son contexte écologique ? En psychologie clinique la perception du temps est souvent abordée à partir des repères séquentiels et des capacités rythmiques mais la sémiologie de « la capacité à ressentir la durée du temps » manque de références développementales. Objectif : instaurer « une sémiologie développementale » de « la perception de l'écoulement du temps » chez des enfants typiques, et rechercher des indices sémiologiques de trajectoires développementales atypiques. Hypothèses cliniques : 1) la « capacité à ressentir l'écoulement du temps » a une réalité clinique déterminable par des « indices sémiologiques » au sein de la réalité écologique d'enfants typiques de 2,5 à 12 ans en population générale, 2) une population d'enfants atypiques présente une clinique et un cours développemental différents. Méthodologie : Un « questionnaire d'anamnèse sémiologique » à remplir par les parents a été développé à partir des observations cliniques des chercheurs. 25 questions approchent une « sémiologie écologique » des attitudes de l'enfant pouvant être liées à la perception du temps. Il a été appliqué dans 2 populations d'enfants de 2,5 à 12 ans : 827 enfants typiques en population générale et 297 enfants atypiques consultant des services de suivis psychologiques ambulatoires (S.S.M) (échantillon transnosographique). Des analyses développementales portent sur 4 populations: garçons typiques, filles typiques, garçons atypiques, filles atypiques. Chaque question est considérée comme une variable ordinale à 5 modalités (échelle de Likert). L'analyse (programme Statistica) procède par régression logistique multinomiale de chaque variable en fonction de l'âge et de deux variables explicatives nominales : enfants atypiques et sexe ; les interactions atypique/sexe/âge sont ensuite analysées. Résultats : les questions sont catégorisées selon: 1) La présence d'une évolution développementale (19 variables/25); 2) Une discrimination de la population atypique (12 variables/25 dont 6 variables ont une évolution développementale spécifique aux atypiques), ce qui constitue un questionnaire de dépistage; 3) Une différenciation sexuée (2 variables sur 25). [less ▲]

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See detailPerception de l'écoulement du temps : une sémiologie développementale de 2,5 à 12 ans, population générale versus atypique
SCHOLL, Jean-Marc ULg; PHILIPPE, Paule ULg

Poster (2011, January)

Introduction : En clinique, la perception du temps chez l'enfant est surtout considérée à partir du temps séquentiel mais il y a une quasi-absence de prise en compte de repères sémiologiques de sa ... [more ▼]

Introduction : En clinique, la perception du temps chez l'enfant est surtout considérée à partir du temps séquentiel mais il y a une quasi-absence de prise en compte de repères sémiologiques de sa capacité d'appréhender la durée du temps. Objectif : Développer une sémiologie développementale de « la perception de l'écoulement du temps » en situation écologique. Méthode : Élaboration d'un « questionnaire sémiologique » de la « capacité à ressentir la durée du temps » à remplir par les parents (échelle de Likert) ; recrutement de 2 échantillons d'enfants de 2,5 à 12 ans : 827 enfants typiques en population générale et 297 enfants atypiques consultant des services de suivis psychologiques ambulatoires (S.S.M.) (échantillon transnosographique) ; régression logistique multinomiale de chaque item en fonction de l'âge et de 2 variables explicatives nominales : population atypique et sexe. Résultats : 19 questions/25 ont une évolution développementale ; 2 questions une différence sexuée ; 12 questions/25 différencient la population atypique. Ces 12 questions permettent de relever une sémiologie cliniquement pertinente qui approche la « capacité de ressentir la durée du temps » en milieu écologique ; en voici quelques exemples : - Quand l’enfant est ailleurs (par exemple à l’école ou à la garde d’une personne), il répète souvent la question de savoir quand on viendra le rechercher bien qu’on lui ait déjà souvent répondu ou qu’il en ait déjà souvent fait l’expérience ? - A-t-il toujours besoin de savoir comment va se dérouler sa journée ? - Lorsqu’une activité est prévue, répète-t-il souvent la question de savoir quand elle aura lieu alors qu’on lui a déjà répondu ? - Votre enfant est-il souvent en retard (et pour cela il faut souvent lui rappeler l'heure)? - Quand votre enfant est occupé à une activité, a-t-il tendance à être surpris quand arrive la fin du temps qui était prévu pour celle-ci (comme s’il n’avait pas anticipé que le temps approche de la fin) ? - Spontanément, sans avoir besoin de regarder l’heure, votre enfant « sent-il » qu’une activité en cours approche de l’heure où on va devoir l’arrêter ? (par exemple, spontanément il ressent l’approche de la fin de l’heure de piscine ; il interrompt à temps son jeu pour aller regarder son émission favorite à la TV). [less ▲]

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See detailDiagnostic différentiel ADHD / Bipolarité par une étude de l'évolution développementale de la sémiologie enfants - adultes
SCHOLL, Jean-Marc ULg; PHILIPPE, Paule ULg

Poster (2011, January)

Introduction : La prévalence du Trouble de l'attention avec ou sans hyperactivité (ADHD, TDA/H) est de 3 à 5 % pour les enfants et de 1,9 à 7,3 % pour les adultes dans différentes pays (Kessler et al ... [more ▼]

Introduction : La prévalence du Trouble de l'attention avec ou sans hyperactivité (ADHD, TDA/H) est de 3 à 5 % pour les enfants et de 1,9 à 7,3 % pour les adultes dans différentes pays (Kessler et al., 2006; Fayyad et al., 2007). Le Trouble bipolaire a une prévalence chez l'adulte de 1 % pour le type I et de 4,4 % pour le spectre bipolaire (Merikangas et al., 2007), chez l'adolescent elle est évaluée à 1 % pour le type I et le spectre bipolaire en population juvénile à 6 % (2 à 15) (Benazzi, 2007). Des controverses demeurent quant au recouvrement de ces différentes entités cliniques selon les âges. Gabrielle Carlson a décrit chez l'enfant un tableau bipolaire comportant des symptômes maniaques continus et chroniques avec des symptômes d'ADHD. Ainsi, le « National Institutes of Health (NIH) » a distingué cette forme continue du trouble dans l'enfance, le « severe mood dysregulation », du trouble bipolaire de type I de l'adolescent, le « narrow phenotype » comportant des épisodes thymiques et davantage de symptômes psychotiques. Dans une population d'enfants maniaques bipolaires les études rapportent 57 à 98 % d'ADHD en comorbidité. Par contre, dans une population d'enfants ADHD, la comorbidité avec les états bipolaires est de 11 à 22 % (Angold et al., 1999 ; Carlson, 1998 ; Singh et al., 2006). Objectif : Affiner « une sémiologie développementale » et le diagnostic différentiel ADHD/Bipolarité Méthode : Étude qualitative avec observation et « anamnèse sémiologique » détaillée d'un maximum de micro-signes ; échantillons: 14 enfants (5 à 10 ans) et 7 adultes (20 à 37 ans) avec ADHD seul et 170 enfants (2 à 10 ans) et 55 adultes (19 à 61 ans) avec des caractéristiques bipolaires (selon le DSM IV). Résultat : Proposition d'un "tempérament maniaque bipolaire simple" en 7 axes sémiologiques : 1. forme super-énergétique, 2. clinique du sommeil, 3. "mal-être en situation d'être seul", 4. labilité émotionnelle, 5. excitabilité-désinhibitions, 6. prépondérance de l'attention divergente sur l'attention convergente, 7. tendance à l'hyperactivité. L'ADHD ne comporte que 1, 6 et 7. Réf.: « Bipolarité et ADHD. Recherche sémiologique : continuum développemental de la petite enfance à l'âge adulte et diagnostic différentiel », La Psychiatrie de l'enfant, vol. 55/2012, in press. [less ▲]

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See detaildoes neoadjuvant radiotherapy promote tumor dissemination ,
Leroi, Natacha ULg; boujouf, Sarah; COUCKE, Philippe ULg et al

Poster (2011, January)

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See detailThe Cenomanian marine reorganization
Fischer, Valentin ULg

Poster (2011, January)

The middle Cretaceous is usually associated with numerous climatic and oceanic perturbations, and a minor to intermediate extinction event at the Cenomanian-Turonian (CTB) boundary. Amongst marine ... [more ▼]

The middle Cretaceous is usually associated with numerous climatic and oceanic perturbations, and a minor to intermediate extinction event at the Cenomanian-Turonian (CTB) boundary. Amongst marine vertebrate palaeontologists, the CTB is mostly known as the extinction of the last ichthyosaurs (Reptilia), after a long period of decline (e.g. Bardet, 1992; Bardet, 1994; Sander, 2000; Lingham-Soliar, 2003). However, new data from France, Canada and Russia indicates that the diversity of late Early Cretaceous ichthyosaurs was far higher than previously thought, both in terms of taxonomical and ecological diversity, but the Cenomanian ichthyosaur diversity remains extremely low. This suggests that the ichthyosaur extinction is far more severe than initially thought and took place during the whole duration of the Cenomanian, in a diachronic fashion. Additionally, a compilation of the current data on the diversity of other marine vertebrates groups shows that the Cenomanian is a peculiar stage within the Cretaceous, with the radiation burst of marine squamates, such as dolichosaurs and mosasauroids (Bardet et al., 2007; Bardet et al., 2008), as well as chondrichtyans, polycotylid plesiosaurs and teleost fishes (e.g. Cumbaa et al., 2010; Schultze et al., 2010). This profound reorganisation of the marine ecosystems (coeval with the onset of the “Chalk sea”) was probably driven by external, physical factors given the diversity of biotic responses. The numerous potential causes for that major reorganisation renders the identification of its precise mechanisms difficult. [less ▲]

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See detailMiR-146a an angiostatic miRNA elevated in peripartum cardiomyopathy
Halkein, Julie ULg; Castermans, Karolien; Malvaux, Ludovic et al

Poster (2011, January)

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See detailSémiologie des troubles de l'attention : attention convergente et attention divergente, continuum développemental de la petite enfance à l'âge adulte.
SCHOLL, Jean-Marc ULg; PHILIPPE, Paule ULg

Poster (2011, January)

Introduction : Le « Trouble de l'attention avec ou sans hyperactivité » (ADHD ou TDA/H) connu chez l'enfant, demeure une clinique peu identifiée à l'âge adulte alors qu'elle persiste dans 50 % des cas ... [more ▼]

Introduction : Le « Trouble de l'attention avec ou sans hyperactivité » (ADHD ou TDA/H) connu chez l'enfant, demeure une clinique peu identifiée à l'âge adulte alors qu'elle persiste dans 50 % des cas (Faraone et al., 2006) ; plus précisément, l'étude de l'évolution comparative des symptômes entre 6 ans et 20 ans révèle que l'hyperactivité diminue de 50 %, l'impulsivité de 40 % et l'inattention ne diminue que de 20 % (Mick et al., 2004). La sémiologie des troubles de l'attention est particulièrement méconnue chez l'adulte, or, elle peut interférer avec le pronostic socio-affectif de la personne (Bange, dans Revol & Brun, 2010). Dans le DSM IV-TR le trouble de l'attention isolé nécessite la présence de 6 des 9 critères d'inattention mentionnés. La littérature évoque aussi une distinction sémiologique en formes « d'attention convergente » et « d'attention divergente » ; ce vocable médical est plus global que celui de la neuropsychologie mais possède un substrat neurophysiologique qu'un traitement spécifique de l'E.E.G. permet de mesurer sur l'ensemble du cortex cérébral par les degrés respectifs d'utilisation de processus convergents et divergents lors de tâches en cours (Arns et al., 2009 ; Van den Bergh, 2003 ; van Dongen-Boomsma et al., 2010). Objectif : Affiner la sémiologie des troubles de l'attention tant chez l'enfant que chez l'adulte. Méthode : 1) une revue de la littérature et 2) une étude d'observation qualitative fine avec une « anamnèse sémiologique » détaillée d'un maximum de micro-signes sémiologiques porte sur 14 enfants, âgés de 5 ans 3 mois à 10 ans 7 mois, et 7 adultes de 20 ans à 37 ans présentant un diagnostic de trouble de l'attention (selon le DSM IV). Résultat : Deux tableaux, selon qu'il y a une prépondérance de « l'attention convergente » ou de « l'attention divergente », donnent un descriptif détaillé de la sémiologie. Ces tableaux sont différenciés chez l'enfant et chez l'adulte ; ils permettent d'établir un continuum développemental de la clinique. Réf. : « Bipolarité et ADHD. Recherche sémiologique : continuum développemental de la petite enfance à l'âge adulte et diagnostic différentiel », La psychiatrie de l'enfant, vol. 55/2012, in press. [less ▲]

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See detailOptimization of a formic/acetic acid treatment of beech wood (Fagus sylvatica L.) for delignification
Simon, Mathilde ULg; Richel, Aurore ULg; Vanderghem, Caroline ULg et al

Poster (2011)

Lignin is a promising molecule constituting a renewable alternative to some petrochemical industry products. Lignin is an aromatic cross-linked heteropolymer composed of three phenylpropanoids (p ... [more ▼]

Lignin is a promising molecule constituting a renewable alternative to some petrochemical industry products. Lignin is an aromatic cross-linked heteropolymer composed of three phenylpropanoids (p-hydroxyphenyl, guaiacyl and syringyl units) linked together via radical coupling reactions by specific ether or carbon-carbon bonds. With this phenylpropanoid structure, lignin is a rich resource of biobased products that could find high-valued applications in a lot of different areas like petrochemical polymer reinforcement and replacement, antioxidants, stabilizers, resins and vanillin production... The first challenge of the valorization of lignins is their extraction from raw materials. Lignins can be found in different lignocellulosic substrates like grasses, softwood and hardwood. This extraction process needs the development of suitable biomass treatments, allowing efficient lignin recuperation without degradation. This one could lead to the loss of some interesting properties and so of some valorization possibilities. In this study, beech wood (Fagus sylvatica L.) was collected in the region of Gaume (Belgium). Beech wood particles were delignified at atmospheric pressure by a mixture of formic acid/acetic acid/water. A central composite design and response surface methodology were used for the optimization of treatment parameters for delignification. The optima of two independent variables, namely time (1h30, 3h, 4h30) and temperature (87°C, 97°C, 107°C), were determined on delignification yield, pulp yield, concentration of degradation products (furfural and hydroxymethylfurfural). Moreover, the impact of these two variables on the amount of residual linkages between phenylpropanoid units was evaluated by semi-quantitative bidimensional nuclear magnetic resonance spectroscopy (NMR-HSQC). Our results highlight that the delignification yields increase when cooking time and temperature are elevated. Nevertheless, under these conditions, pulp yield decreases as hydrolysis of hemicelluloses and cellulose occurs. The hydrolysates of carbohydrates (free sugars or oligosaccharides) are contained in the black liquor. At elevated temperature and time, the amount of degradation products in the black liquor is increased. [less ▲]

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See detailThe influence of affective valence on DRM false memories in younger and older adults
Dehon, Hedwige ULg; Laroi, Frank; Van der Linden, Martial

Poster (2011)

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See detailTowards laser cooling of Iron Atoms
Huet, Nicolas ULg; Krins, Stéphanie ULg; Bastin, Thierry ULg

Poster (2011)

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See detailPoultry supply chains and demand analysis for poultry meat in the context of HPAI in Hanoi, North-Vietnam
Vu Dinh, Ton; Phan Dang, Thang; Nguyen Tuan, Son et al

Poster (2011)

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See detailConstruction and validation of a new perceptual priming task: The contrasted word task
Geurten, Marie ULg; Meulemans, Thierry ULg

Poster (2011)

In clinical neuropsychology, different rehabilitation techniques – e.g., vanishing cues, spaced retrieval, errorless learning – developed for patients with memory impairments are considered to make use of ... [more ▼]

In clinical neuropsychology, different rehabilitation techniques – e.g., vanishing cues, spaced retrieval, errorless learning – developed for patients with memory impairments are considered to make use of the preserved implicit memory abilities shown by these patients, and notably the perceptual priming effects (Harrison et al., 2007). It might be therefore important for clinician neuropsychologists to determine whether these abilities are preserved or not in their patients. However, and quite surprisingly, assessment tools aimed at assessing implicit memory abilities in brain damaged patients are lacking. The aim of this study was to build and validate a new perceptual priming task – the contrasted word task – which could be used by neuropsychologists in their clinical practice. Seventy-two young healthy participants were included in this study, and were administered the contrasted word task in which 60 words counterbalanced in 2 orders and 3 types of priming (Visual; Auditory; New) emerged gradually from a white background on a computer screen. Subjects were asked to press the response key when they thought they had recognized the word. Results show a perceptual priming effect which is specific to the exposure modality (i.e., no inter-modality transfer), proving the efficacy of the contrasted word task to highlight a facilitated identification for words that were shown previously, and confirming the perceptual specificity of the priming effect (Schacter, 1992). [less ▲]

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See detailSélection et traitement thermique de matériaux colorants rouges sur le site moustérien es-Skhul (ca. 100 000 B.P., Israël)
Salomon, Hélène ULg; Vignaud, Colette; d'Errico, Francesco et al

Poster (2011)

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See detailL'origine des hématites oolithiques exploitées durant la Préhistoire récente. Objectifs et méthodes d'un PCR
BILLARD, Cyrille; SAVARY; GOEMAERE, Eric et al

Poster (2011)

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See detailDevelopment of a LC-UV-MS analytical method for malondialdehyde.
Douny, Caroline ULg; Dure, Remy; Brose, François ULg et al

Poster (2011)

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See detailInfection néonatale tardive : Méningite à Streptocoque Agalactiae chez un nouveau-né de 19 jours.
Bequet, Emeline ULg; Guffens, Anne; Defontaine, Elizabeth et al

Poster (2011)

Les infections à Streptocoques du groupe B (SGB ou Streptococcus Agalactiae) sont, dans 80% des cas, précoces (< 7jours de vie) et, dans 20% des cas, tardives (> 7 jours de vie). Dans cette seconde ... [more ▼]

Les infections à Streptocoques du groupe B (SGB ou Streptococcus Agalactiae) sont, dans 80% des cas, précoces (< 7jours de vie) et, dans 20% des cas, tardives (> 7 jours de vie). Dans cette seconde catégorie, 35% des infections sont des méningites et engendrent une morbidité importante chez l’enfant. Nous présentons le cas d’un garçon de 19 jours, né à terme par césarienne, ayant développé une méningite à Streptocoques B, avec un dépistage maternel négatif. A l’admission, l’enfant est septique. Un bilan complet met en évidence une méningite à Streptocoque Agalactiae. Une antibiothérapie empirique à base d’Ampicilline 200mg/kg/j, Céfotaxime 100mg/kg/j et Amikacine 15mg/kg/j est initiée. Ce traitement est maintenu 5 jours ; ensuite, poursuite du Céfotaxime en monothérapie pour une durée totale de 14 jours. Les complications précoces (présentes dans 62% des cas) ne sont pas mises en évidence par les différentes explorations réalisées : mesure du périmètre crânien ; échographie transfontanellaire à la recherche d’une hydrocéphalie ou d’abcès cérébraux ; électroencéphalogramme pour exclure des phénomènes paroxystiques. A moyen et long terme, une surveillance clinique, iconographique, ophtalmologique et de l’audiogramme devra être faite afin d’exclure un retard développemental, des troubles sensoriels ainsi qu’une hydrocéphalie, une encéphalomalacie, une atrophie cérébrale ou une porencéphalie. L’incidence des infections précoces à streptocoques B a pu être réduite grâce au dépistage maternel anténatal et à une antibioprophylaxie en cas de positivité du test. Cependant, l’administration perpartale systématique d’antibiotiques ne permet pas de diminuer le nombre et la gravité des infections tardives, la contamination étant, dans ces cas, essentiellement horizontale. Le taux de complications à 5 ans des méningites à SGB est estimé à 49%, ce qui justifie, chez ces enfants, un suivi neuropédiatrique et sensoriel à long terme. [less ▲]

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See detailNanobodies as structural probes to investigate the mechanism of fibril formation by the amyloidogenic variants of human lysozyme
Dumont, Janice ULg; Pardon, Els; Aumont-Nicaise, Magalie et al

Poster (2011)

Six variants of human lysozyme (single-point mutations I56T, F57I, W64R, D67H and double mutations F57I/T70N, W112R/T70N) are associated with a hereditary non-neuropathic systemic amyloidose. These ... [more ▼]

Six variants of human lysozyme (single-point mutations I56T, F57I, W64R, D67H and double mutations F57I/T70N, W112R/T70N) are associated with a hereditary non-neuropathic systemic amyloidose. These proteins form extracellular amyloid fibrils that deposit in a wide range of tissues and organs such as liver, spleen and kidneys where they cause damages [1]. It was shown that the D67H and I56T mutations cause a loss in stability and more particularly a loss of global cooperativity of protein [1]. Consequently, under physiologically relevant conditions, these variants can transiently populate a partially unfolded state in which the beta-domain and the C-helix are cooperatively unfolded while the rest of the protein remains native like [1]. The formation of intermolecular interactions between the regions that are unfolded in this intermediate state is likely to be a fundamental trigger of the aggregation process that ultimately leads to the formation and deposition of fibrils in tissues. We have also shown that the binding of three variable domain of camelid antibodies or (VHHs) - raised against the wild type human lysozyme inhibit in vitro the formation of amyloid fibrils by the lysozyme variants. These three VHHs bind on different regions of lysozyme and act as amyloid fibrils inhibitor through different mechanisms [2, 3, and unpublished results]. In the present work, sixteen new VHHs specific of human lysozyme have been generated. Competition experiments have shown that they bind to five non overlapping epitopes. We have demonstrated that five of these new VHHs are able to bind lysozyme in conditions used for amyloid fibril formation, and interestingly two of them recognize two epitopes that are different from those of the three VHHs previously characterized [2, 3, and unpublished results]. The effects of these new VHHs on the properties of lysozyme variants such as activity, stability, cooperativity and aggregation will be discussed. [less ▲]

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See detailModernization of demand analysis for poultry meat in the context of HPAI in Hanoi, North-Vietnam
Phan Dang, Thang; Nguyen Tuan, Son; Bui Huu, Doan et al

Poster (2011)

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See detailResting-state fMRI activity in tinnitus
Maudoux, Audrey ULg

Poster (2011)

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See detailA chaque abeille son stérol et ses fleurs
Vanderplanck, Maryse ULg; Lognay, Georges ULg

Poster (2011)

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See detailCT Peritoneography: Normal Anatomy of the Peritoneal Cavity and Implications for Diseases Assessment
OUHADI; MATERNE, R; GHEKIERE, O et al

Poster (2011)

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See detailMorphology of the suspensory ligament (interosseous muscle III) of the horse
Shikh Al Sook, Mohamad Khir ULg; Espinosa, Jennifer; Piret, Joëlle ULg et al

Poster (2011)

Introduction: The injuries of the suspensory ligament (SL) are important causes of lameness and financial losses in the equine industry. Ultrasound examination permitted to visualize some parts of the SL ... [more ▼]

Introduction: The injuries of the suspensory ligament (SL) are important causes of lameness and financial losses in the equine industry. Ultrasound examination permitted to visualize some parts of the SL. The significance of “abnormal” findings is however not sufficiently known. Until now, few studies described the relationship between the ultrasonographic appearance and the exact morphology in histological sections. The aim of this study is to develop good techniques for cutting and staining the SL and to improve knowledge about the normal morphology of the SL. Methods: In this study, the SL of eight <sound> horses were collected. The body of the SL was divided in 3 thirds and sampling was realised within each third and between the thirds. The samples were embedded in paraffin or in Tissue-Tek for cryosections. The sections were stained with hematoxylin/eosin or Masson's trichrome. For 3 SL, ultrasounds were performed before sampling. The digital tip was maintained in physiological position owing to a press. Results: Most of the paraffin sections were shredded because of the hardness of the tissue. Cryosection revealed a better preservation of tissues. Only some freezing artifacts (holes) appeared on a few sections. Muscles fibers surrounded by adipose tissue containing blood vessels were present mainly in the proximal and medium third of the SL whereas they were not found in the distal third. The remaining structure look like a tendon and was composed of collagen fibers, stained in green with the Masson's trichrome coloration. Conclusions: This study permitted to develop cutting and staining techniques for the SL and helped to map the adipose, muscular and tendinous parts within the SL. It lays down the bases of subsequent studies that will concern ultrasonographically examined digital tips of sound and pathological horses of different breeds and ages. [less ▲]

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See detailEffects of environmental factors on yield and milking number in dairy cows milked by an automatic system located in pasture
Dufrasne, Isabelle ULg; Robaye, Vincent ULg; Knapp, Emilie ULg et al

Poster (2011)

Nowadays, farmers have to manage larger herds but want, at the same time, benefit from a normal social life. The milking robot can bring solutions. Its use can reduce physical labour and allow flexibility ... [more ▼]

Nowadays, farmers have to manage larger herds but want, at the same time, benefit from a normal social life. The milking robot can bring solutions. Its use can reduce physical labour and allow flexibility. This technology results in a reduction in grazing even through grazing appears as a natural practice which is appreciated by the consumers. This project aims to develop strategies to use milking robots in pasture in order to benefit from advantages regarding feeding costs as well as animal welfare and health. It aims to study the effects of grass height, animal, days in milk, rotation cycle number and distance from grazed paddocks on daily milk yield and milking number of grazed cows. [less ▲]

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See detailA Chandra search for low-mass companions of late B-stars in Tr16
Evans, N. R.; DeGioia-Eastwood, K.; Gagné, M. et al

Poster (2011)

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See detailMassive non-thermal radio emitters: new data and their modelling
Volpi, D.; Blomme, R.; De Becker, Michaël ULg et al

Poster (2011)

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See detailPostglacial pioneer settlement in the Sarvinki area, Eastern Finland : a red ochre grave in Rahakangas 1 site
Simponen, Laija; Mannermaa, Kristiina; Taipale, Noora ULg et al

Poster (2011)

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See detailOPTIMIZATION OF A NEW TWO-PLATE SCREENING METHOD FOR THE DETECTION OF ANTIBIOTIC RESIDUES IN MEAT.
Pham Kim, Dang; Degand, Guy ULg; Danyi, Sophie et al

Poster (2011)

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See detailCompelling untruths: the effect of aging on vivid false memories and memory editing
Dehon, Hedwige ULg; Lampinen, James Michael

Poster (2011)

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See detailImpact of the treatment conditions of a formic/acetic acid delignification method on chemical structure and antioxidant activity of beech wood lignin
Simon, Mathilde ULg; Vanderghem, Caroline ULg; Richel, Aurore ULg et al

Poster (2011)

The interest in lignocellulosic substrates is increasing because they are clearly identified for their high potential of development in energy and value-added molecules production. Indeed lignocellulosic ... [more ▼]

The interest in lignocellulosic substrates is increasing because they are clearly identified for their high potential of development in energy and value-added molecules production. Indeed lignocellulosic biomass constitutes a promising resource for a sustainable production of organic compounds and biobased products that could progressively replace molecules from the petrochemical industry. Until now lignocellulosic substrates were mainly used for the valorization of cellulose. Hemicelluloses and lignins were less valorized and often degraded after the process. However, due to their phenolic structure, lignins can be valorized in a lot of high-valued applications like vanillin production, replacement of petrochemical polymers, antioxidants for cosmetics and food industry, resins… In this study, a representative sample of beech wood (Fagus sylvatica L.) was collected in the region of Gaume in Belgium. Beech wood was delignified at atmospheric pressure by an organosolv process using a mixture of formic acid/acetic acid/water. The effect of cooking time and temperature was evaluated on the structure, physico-chemical properties and antioxidant activity of the lignins obtained from the black liquor after treatments. The structural and physico-chemical characteristics of the lignins were investigated with different tools like infrared spectrometry, thermogravimetric analysis, gel permeation chromatography after acetylation of lignins, NMR 1H, 13C and HSQC. The antioxidant activity was assessed by a spectrophotometric method using the α,α-diphenyl-β-picrylhydrazyl radical (DPPH). [less ▲]

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See detailLa cartographie des forêts anciennes en Wallonie
Kervyn, Thierry; Branquart, Etienne; Dufrêne, Marc ULg

Poster (2011)

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See detailDark matter in a SUSY left-right theory
Vicente, Avelino ULg

Poster (2011)

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See detailAdenylation domain specificity in pyoverdine NRPS biosynthesis
Vanvlassenbroeck, Aurélien; Leclère, Valérie; Pupin, Maude et al

Poster (2011)

Detailed reference viewed: 29 (3 ULg)